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Chemistry-Biology Interface Predoctoral Training Grant

化学-生物界面博士前培训补助金

基本信息

批准号：
10618976
负责人：
ERIC Robert STRIETER
金额：
$ 53.05万
依托单位：
UNIVERSITY OF MASSACHUSETTS AMHERST
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-07-01 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10618976
关键词：
Biology Chemistry Grant Training pre-doctoral

项目摘要

PROJECT SUMMARY Twenty-five years ago, the University of Massachusetts launched a training program at the interface of chemistry and biology. The program built on existing strengths and harnessed our commitment to building bridges between the physical and life sciences. Since then, the University of Massachusetts has undergone a complete transformation in the life sciences. Massive investments in state-of-the-art core facilities and research buildings coupled with the hiring of over 50 new faculty has revolutionized the research capacity on campus. By establishing a collaborative community and interdisciplinary curriculum, the Chemistry-Biology Interface (CBI) training program has been at the center of this growth. The 31 CBI Training Faculty now train a total of 162 talented students, 54 of whom are eligible for support from the CBI training grant. CBI students come from five participating graduate programs: Chemistry, Chemical Engineering, Microbiology, Molecular & Cellular Biology, and Polymer Science & Engineering. The CBI curriculum is designed to complement the requirements of these programs, to achieve four objectives: 1) to provide fluency in both chemistry and biology concepts, tools, and opportunities; 2) to communicate and collaborate effectively with scientists from diverse chemistry and biology research backgrounds; 3) to follow best practices in performing rigorous and reproducible research; and 4) to increase awareness of career opportunities and build the appropriate skills to network effectively in order to take advantage of these opportunities. Robust participation of ~ 60 CBI student members who complete the curriculum, regardless of funding, demonstrates the perceived high value of this training. In this proposal, we seek to enhance the training capacity of the CBI program by requesting twelve trainee slots, which will be matched with four slots annually from UMass. Over the next five years, the cohort of CBI trainees will participate in several innovative training activities, including a revised curriculum incorporating the principles of rigor and reproducibility, specialized laboratory modules designed to introduce trainees to new concepts and techniques, and a biennial Alumni Symposium where current trainees will have the opportunity to connect with our network of 143 alumni. Equipped with this comprehensive skillset, graduates from our CBI program will be well-prepared to solve frontier problems in biology and biomedicine.

项目摘要 25年前，马萨诸塞州大学启动了一项培训计划，化学和生物学。该计划建立在现有的优势，并利用我们的承诺，物理科学和生命科学之间的桥梁。从那时起，马萨诸塞州大学经历了一个生命科学的彻底变革。对最先进的核心设施和研究的大量投资建筑物加上雇用了50多名新教师，彻底改变了校园的研究能力。通过建立合作社区和跨学科课程，化学生物学接口 (CBI)培训计划是这一增长的核心。CBI的31个培训学院现在总共培训了 162名有才华的学生，其中54人有资格获得CBI培训补助金的支持。CBI学生来自五个参与研究生课程：化学，化学工程，微生物学，分子与细胞生物学和高分子科学与工程。CBI课程旨在补充要求这些计划，以实现四个目标：1）提供流利的化学和生物学概念，工具和机会; 2）与来自不同化学领域的科学家进行有效的沟通和合作和生物学研究背景; 3）遵循严格和可重复的最佳实践研究;以及4）提高对职业机会的认识，并建立适当的网络技能有效地利用这些机会。约60名CBI学生成员的强劲参与无论资金情况如何，完成课程的人数都表明了这种培训的高价值。在在这个建议中，我们寻求通过要求12个实习生名额来提高CBI计划的培训能力，这将是匹配的四个插槽每年从麻省大学。在接下来的五年里，加调局的学员将参加一些创新的培训活动，包括修订课程，严格性和可重复性的原则，专门的实验室模块，旨在向学员介绍新的概念和技术，以及两年一度的校友研讨会，目前的学员将有机会与我们的143名校友的网络连接。配备了这种全面的技能，从我们的CBI毕业生该计划将为解决生物学和生物医学的前沿问题做好充分准备。

项目成果

期刊论文数量（21）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Macrophage-Encapsulated Bioorthogonal Nanozymes for Targeting Cancer Cells.

DOI：
10.1021/jacsau.2c00247
发表时间：
2022-07-25
期刊：
JACS AU
影响因子：
8
作者：
Das, Riddha;Hardie, Joseph;Joshi, Bishnu P;Zhang, Xianzhi;Gupta, Aarohi;Luther, David C;Fedeli, Stefano;Farkas, Michelle E;Rotello, Vincent M
通讯作者：
Rotello, Vincent M

Biomimetic and bioorthogonal nanozymes for biomedical applications.