Data Repository-Core

数据存储库核心

• 批准号: 10202578
• 负责人: Shankar Subramaniam
• 金额: $ 170.51万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-17 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10202578
• 关键词: Address; Architecture; Biomedical Research; Clinical; Clinical Data; Cloud Computing; Collaborations; Communities; Companions; Consultations; Data; Data Analyses; Databases; Development; Environment; Evaluation; FAIR principles; Foundations; Governing Board; Health; Human; Human Resources; Hybrids; Image; Infrastructure; International; Lead; Link; Maintenance; Manuals; Mass Spectrum Analysis; Measurement; Measures; Metadata; Methods; Ontology; Pathway interactions; Physiology; Protocols documentation; Recommendation; Research; Research Design; Site; Stable Isotope Labeling; Structure; Time; Visualization; Vocabulary; computer infrastructure; data format; data harmonization; data infrastructure; data integration; data repository; data resource; data standards; data structure; data tools; design; interoperability; metabolomics; next generation; novel; ontology development; pathway tools; portability; relational database; repository; statistics; stem; structured data; supercomputer; tool; tool development; web page; web site

Project Summary The Data Repository Core serves as the essential foundation of the NMDR. The objective of the data repository core is the continuation and substantial enhancement of the Metabolomics Workbench into the next generation. In order to achieve this, the data repository core personnel will carry out the following: • Develop additional strategies for study capture and methods to harmonize the data in the nextgen MW. • Design metadata/data standards and requirements in consultation with the SEPCC and Governing Board. • Generate tools for curation of submitted data through multiple mechanisms, ranging from automatic to manual. • Provide the community easily accessible mechanisms to evaluate the nextgen MW, i.e., the data, tools, and interfaces on the MW. • Transition the data and computational infrastructure into next generation. The current MW resides in the San Diego Supercomputer Center Cloud and we will adapt the nextgen MW to portable, hybrid cloud environments. • Expand the database to incorporate novel types of data and metadata from new measurements. • Create easy to use interfaces that will facilitate query, analysis, and visualization. • Incorporate publicly available tools, upon recommendations from SEPCC, into the nextgen MW through development of adaptable Application Programmer Interfaces (APIs). • Build mechanisms to help the community interoperate and harmonize metabolomics data with extant data resources.

项目摘要 数据存储库核心是NMDR的重要基础。数据存储库的目标 核心是代谢组学的延续和实质性增强，进入下一代。 为实现这一目标，数据储存库核心人员将开展以下工作： ·制定额外的研究捕获策略和方法，以协调下一代MW中的数据。 ·设计元数据/数据标准和要求与SEPCC和管理咨询 纸板. ·通过多种机制生成工具，用于管理提交的数据，从自动到 手册. ·为社区提供易于使用的机制，以评估下一代MW，即，数据，工具， 和MW上的接口。 ·将数据和计算基础设施过渡到下一代。当前MW位于 圣地亚哥超级计算机中心云，我们将使下一代MW适应便携式混合云 环境. ·扩大数据库，纳入新的测量数据和元数据的新类型。 ·创建易于使用的界面，方便查询，分析和可视化。 ·根据SEPCC的建议，将公开可用的工具纳入下一代MW， 开发适应性强的应用程序接口（API）。 ·建立机制，帮助社区与现有的代谢组学数据进行互操作和协调 数据资源。