The Metabolomics Data Center and Workbench (MDCW)

描述（由申请人提供）：该提案的目标，代谢组学数据中心和工作台（MDCW），是创建一个可扩展和可扩展的信息学基础设施，将作为国家代谢组学资源。这是RCMRCs的配套提案，是代谢组学共同基金倡议的一部分。拟议的MDCW将协调国家和国际代谢组学中心和倡议的数据活动，作为国家数据存储库，并开发一个工作台，该工作台将具有数据，查询和分析接口，以及用于代谢组学数据交互分析和集成的工具。提议的工作将建立在PI实验室开发的现有脂质基础设施上，作为NIH脂质组学胶水资助计划的一部分。该提案的具体目标是：a)开发代谢组学数据存储库、工具和接口；b)为代谢组学开发云计算基础设施；c)协调RCMRCs和其他代谢组学计划；d)为推进代谢组学教育和研究提供资源，以实现新的生物医学。

DESCRIPTION (provided by applicant): The objective of this proposal, Metabolomics Data Center and Workbench (MDCW), is the creation of a scalable and extensible informatics infrastructure which will serve as a national metabolomics resource. This is a companion proposal to RCMRCs and is a part of the Common Fund Initiative in metabolomics. The proposed MDCW will coordinate data activities of national and international metabolomics centers and initiatives, serve as a national data repository and develop a Workbench that will have data, query and analysis interfaces, and tools for interactive analysis and integration of metabolomics data. The proposed work will build on the extant infrastructure for lipids developed by the PI's laboratory as a part of the NIH Glue Grant initiative on Lipidomics. The specific objectives of this proposal are, a) development of a metabolomics data repository, tools and interfaces, b) develop a cloud computing infrastructure for metabolomics, c) coordinate RCMRCs and other metabolomics initiatives and d) provide the resources for advancing metabolomics education and research to enable new biomedicine. PUBLIC HEALTH RELEVANCE: The major aim of this proposal is the development of a community-driven data repository for metabolomics. More specifically, the proposed Center will coordinate informatics efforts of RCMRCs and present all data from the Cores and other metabolomics efforts to the biomedical research community. In addition, the proposal will build a computational infrastructure that will be appropriate for metabolomics research. Most importantly, the Center will provide the enabling informatics infrastructure for next generation biomedical research involving metabolomics.