Biomedical Research Excellence, Epigenomics of Development and Disease

北达科他大学 发育与疾病的表观遗传学 行政核心 摘要 行政核心的目标是促进 COBRE 的成长和成功，以 通过整合、集中和管理所有必要的内容来研究发育和疾病的表观基因组学 资源。该核心将支持研究人员的工作重点是表观遗传机制 发育和疾病模型的变化。确保我们的研究人员取得成功并促进长期 我们的计划的可持续性和发展，我们将为必要的项目提供行政和/或财务支持 我们小组活动的各个方面。具体包括： (1) 全面落实 为我们的项目负责人在其职业生涯的多个阶段提供个性化的指导计划，(2) 提供 通过内部顾问委员会、外部顾问对指导计划进行监督和评估 董事会和联合国开发计划署教育资源部，(3) 资助以表观遗传学为中心的新研究项目 通过试点拨款支持，（4）招募新的研究人员，其研究是 专注于使用独特的疾病模型系统来理解表观遗传机制，（5）提供 建立和促进富有成效的科学互动的结构化机会（例如研讨会、座谈会） (6) 通过继续表观遗传学，增强 UND 更广泛的表观遗传学社区 主题研讨会和专题讨论会，(7) 提高表观遗传学小组的国家形象，(8) 提供 对基因组学核心及其相关培训活动的行政支持，以及 (9) 福斯特增加 与其他 UND 和区域团体的合作，包括 UND COBRE、ND INBRE、DACCOTA 等。 这些功能将增强我们执行创新、高质量研究的能力，从而增加 了解病理生理条件下的表观遗传机制，具有未来的潜力 治疗和临床应用。

UNIVERSITY OF NORTH DAKOTA EPIGENOMICS OF DEVELOPMENT AND DISEASE ADMINISTRATIVE CORE SUMMARY The goal of the Administrative Core is to promote the growth and success of the COBRE centered on the Epigenomics of Development and Disease by consolidating, centralizing and managing all necessary resources. The core will support investigators whose work focuses on mechanisms underlying epigenetic changes in models of development and disease. To ensure success of our researchers and promote long-term sustainability and growth of our program, we will provide administrative and/or financial support for essential aspects of our group’s activities. These include the following: (1) Implement a comprehensive and individualized Mentoring Program for our Project Leaders at multiple stages of their careers, (2) Provide oversight and evaluation of the Mentoring Program through the Internal Advisory Board, External Advisory Board, and UND Department of Education Resources, (3) Fund new research projects centered on epigenetics of disease and development though Pilot Grant support, (4) Recruit new investigators whose research is focused on understanding epigenetic mechanisms using unique model systems of diseases, (5) Provide structured opportunities (e.g. seminars, symposia) to establish and facilitate productive scientific interactions within the group, (6) Enhance the wider epigenetics community at UND through continuation of epigenetics- themed seminars and symposia, (7) Raise the national profile of the epigenetics group, (8) Provide administrative support for the Genomics Core and its associated training activities, and (9) Foster increased collaborations with other UND and regional groups including UND COBRE, ND INBRE, DACCOTA, etc. These functions will enhance our ability to execute innovative, high-quality research that will lead to increased understanding of epigenetic mechanisms in pathophysiological conditions, with the potential for future therapeutic and clinical applications.