Biomedical Research Excellence, Epigenomics of Development and Disease

北达科他州大学 发育与疾病的表观基因组学 行政核心 摘要 行政核心的目标是促进科布雷的成长和成功，以 通过整合、集中和管理一切必要的手段，研究发展和疾病的表观基因组学 资源。核心将支持研究人员，他们的工作重点是表观遗传学的潜在机制 发展模式和疾病模式的变化。确保我们的研究人员取得成功，促进长期 为了我们计划的可持续性和增长，我们将为Essential提供行政和/或财务支持 我们小组活动的各个方面。包括以下几个方面：(一)全面落实 为我们的项目负责人提供职业生涯多个阶段的个性化指导计划，(2)提供 通过内部咨询委员会、外部咨询委员会对指导方案进行监督和评价 董事会和新德里大学教育资源部，(3)资助以表观遗传学为中心的新研究项目 通过试点赠款支持疾病和发展，(4)招募新的研究人员，其研究 侧重于使用独特的疾病模型系统来理解表观遗传机制，(5)提供 有组织的机会(如研讨会、座谈会)，以建立和促进富有成效的科学互动 在集团内，(6)通过延续表观遗传学，加强UND更广泛的表观遗传学社区- 主题研讨会和专题讨论会，(7)提高表观遗传学小组的全国形象，(8)提供 对基因组学核心及其相关培训活动的行政支助，以及(9)福斯特增加 与其他联合国开发计划署和区域组织的合作，包括联合国开发计划署科布雷、联合国开发计划署、非洲发展合作组织等。 这些功能将增强我们执行创新、高质量研究的能力，这将导致 对病理生理条件下的表观遗传机制的理解，以及未来的潜力 治疗和临床应用。

UNIVERSITY OF NORTH DAKOTA EPIGENOMICS OF DEVELOPMENT AND DISEASE ADMINISTRATIVE CORE SUMMARY The goal of the Administrative Core is to promote the growth and success of the COBRE centered on the Epigenomics of Development and Disease by consolidating, centralizing and managing all necessary resources. The core will support investigators whose work focuses on mechanisms underlying epigenetic changes in models of development and disease. To ensure success of our researchers and promote long-term sustainability and growth of our program, we will provide administrative and/or financial support for essential aspects of our group’s activities. These include the following: (1) Implement a comprehensive and individualized Mentoring Program for our Project Leaders at multiple stages of their careers, (2) Provide oversight and evaluation of the Mentoring Program through the Internal Advisory Board, External Advisory Board, and UND Department of Education Resources, (3) Fund new research projects centered on epigenetics of disease and development though Pilot Grant support, (4) Recruit new investigators whose research is focused on understanding epigenetic mechanisms using unique model systems of diseases, (5) Provide structured opportunities (e.g. seminars, symposia) to establish and facilitate productive scientific interactions within the group, (6) Enhance the wider epigenetics community at UND through continuation of epigenetics- themed seminars and symposia, (7) Raise the national profile of the epigenetics group, (8) Provide administrative support for the Genomics Core and its associated training activities, and (9) Foster increased collaborations with other UND and regional groups including UND COBRE, ND INBRE, DACCOTA, etc. These functions will enhance our ability to execute innovative, high-quality research that will lead to increased understanding of epigenetic mechanisms in pathophysiological conditions, with the potential for future therapeutic and clinical applications.