CCCEH ECHO COVID19 Supplement

项目摘要/摘要 在ECHO联盟中，哥伦比亚儿童环境健康中心(CCCEH)有三个 纵向妊娠队列主要由非裔美国人和西班牙裔母亲及其 儿童，他们是从1998年开始在怀孕期间被招募的。这三个群体跨越了Echo生命的各个阶段 并代表了在科学研究中通常被低估的城市少数群体。2019年 新型冠状病毒(新冠肺炎)大流行已在全球范围内影响；期间，纽约市 (纽约市)被确定为美国震中。有许多早期指标表明，城市少数民族 社区是受新冠肺炎大流行影响最大的社区之一；接触 大流行因生命阶段而异。制定缩小这些差距的战略，并更充分地了解 新冠肺炎对生活在受影响最严重社区的儿童健康和福利的影响 在这场大流行中，我们小组正在为3个回声补充概念做出贡献。总而言之，这些概念 应对新冠肺炎大流行对ECHO范围内几乎每个结果领域的影响：围产期； 呼吸系统；神经发育；和积极的健康结果。具体地说，目标涉及以下方面的影响 感染；大流行病及其相关政策(如封锁)对环境的更广泛影响 健康的决定因素；以及对健康的社会决定因素的影响。与回声完全一致 关于特派团，这项提案涉及接触新冠肺炎病毒和同时流行的影响- 环境化学和心理社会环境的相关变化对儿童健康、发育、 以及城市和少数族裔社区的整体和福祉。鉴于新冠肺炎的长期影响 对于大流行，关键是要了解这些因素如何影响ECHO衡量的儿童结果， 特别是在研究人群中可能受到最大影响的一部分人群中。 总体而言，我们的建议寻求从大流行中吸取教训，并以此为契机，为未来提供信息。 制定更有效的方案和政策，保护和支持所有儿童，特别是最 很脆弱。

PROJECT SUMMARY/ABSTRACT Within the ECHO consortium, Columbia Center for Children’s Environmental Health (CCCEH) has three longitudinal pregnancy cohorts comprised primarily of African American and Hispanic mothers and their children, who were recruited during pregnancy beginning in 1998. The three cohorts span all ECHO life stages and represent an urban, minority population that is typically under-represented in scientific research. The 2019 novel coronavirus (COVID-19) pandemic has had worldwide impact; during the “first wave”, New York City (NYC) was identified as the U.S. epicenter. There are many early indicators suggesting that urban minority communities were among the most affected by the COVID-19 pandemic; and effects of exposure to the pandemic vary by life stage. To develop strategies to mitigate these disparities and to more fully understand the impact of COVID-19 on the health and welfare of children living in the most affected communities during this pandemic, our group is contributing to 3 ECHO supplement concepts. Collectively, these concepts address the impact of the COVID-19 pandemic on nearly every outcome domain within ECHO: perinatal; respiratory; neurodevelopmental; and positive health outcomes. Specifically, the aims address the impact of infection; the broader impact of the pandemic and its associated policies (e.g., lockdowns) on environmental determinants of health; and the impact on social determinants of health. In complete alignment with the ECHO mission, this proposal addresses the impact of exposure to the COVID-19 virus and concurrent pandemic- related changes in the environmental chemical and psychosocial environments on child health, development, and well-being overall and within urban, minority communities. Given the long-lasting impact of the COVID-19 pandemic, it is critical to understand how these factors influence child outcomes measured in ECHO, particularly among a subgroup of the study population that may be among the most highly impacted. Collectively, our proposal seeks to learn from the pandemic, using it as an opportunity to inform the future development of more effective programs and policies that protect and support all children, especially the most vulnerable.