CCCEH ECHO COVID19 Supplement

项目概要/摘要 在ECHO联盟内，哥伦比亚儿童环境健康中心（CCCEH）有三个 纵向妊娠队列主要包括非裔美国人和西班牙裔母亲及其 从1998年开始，这些儿童在怀孕期间被招募。这三个队列涵盖了ECHO的所有生命阶段 代表了城市的少数民族人口，他们在科学研究中的代表性通常不足。2019年 新型冠状病毒（COVID-19）大流行已产生全球影响;在“第一波”期间，纽约市 (NYC)被确认为美国的震中有许多早期指标表明，城市少数民族 社区是受COVID-19大流行影响最严重的社区之一; 流行病因生命阶段而异。制定战略，以减轻这些差距，并更充分地了解 2019冠状病毒病对生活在受影响最严重社区的儿童的健康和福利的影响， 在这场流行病中，我们的集团正在贡献3个ECHO补充概念。总的来说，这些概念 解决COVID-19大流行对ECHO内几乎每个结果领域的影响：围产期; 呼吸;神经发育;和积极的健康结果。具体而言，这些目标涉及以下方面的影响： 感染;流行病及其相关政策的更广泛影响（例如，封锁）对环境 健康的决定因素;以及对健康的社会决定因素的影响。与欧共体人道处完全一致 使命，该提案解决了暴露于COVID-19病毒和并发大流行的影响- 环境化学和心理社会环境对儿童健康、发育 以及城市和少数民族社区的整体和福祉。鉴于COVID-19的长期影响， 流行病，关键是要了解这些因素如何影响儿童的结果，在ECHO衡量， 特别是在研究人群中可能受影响最大的亚组中。 总的来说，我们的建议寻求从这一流行病中吸取教训，并将其作为一个为未来提供信息的机会 * 制定更有效的方案和政策，保护和支持所有儿童，特别是最不发达国家的儿童， 脆弱

PROJECT SUMMARY/ABSTRACT Within the ECHO consortium, Columbia Center for Children’s Environmental Health (CCCEH) has three longitudinal pregnancy cohorts comprised primarily of African American and Hispanic mothers and their children, who were recruited during pregnancy beginning in 1998. The three cohorts span all ECHO life stages and represent an urban, minority population that is typically under-represented in scientific research. The 2019 novel coronavirus (COVID-19) pandemic has had worldwide impact; during the “first wave”, New York City (NYC) was identified as the U.S. epicenter. There are many early indicators suggesting that urban minority communities were among the most affected by the COVID-19 pandemic; and effects of exposure to the pandemic vary by life stage. To develop strategies to mitigate these disparities and to more fully understand the impact of COVID-19 on the health and welfare of children living in the most affected communities during this pandemic, our group is contributing to 3 ECHO supplement concepts. Collectively, these concepts address the impact of the COVID-19 pandemic on nearly every outcome domain within ECHO: perinatal; respiratory; neurodevelopmental; and positive health outcomes. Specifically, the aims address the impact of infection; the broader impact of the pandemic and its associated policies (e.g., lockdowns) on environmental determinants of health; and the impact on social determinants of health. In complete alignment with the ECHO mission, this proposal addresses the impact of exposure to the COVID-19 virus and concurrent pandemic- related changes in the environmental chemical and psychosocial environments on child health, development, and well-being overall and within urban, minority communities. Given the long-lasting impact of the COVID-19 pandemic, it is critical to understand how these factors influence child outcomes measured in ECHO, particularly among a subgroup of the study population that may be among the most highly impacted. Collectively, our proposal seeks to learn from the pandemic, using it as an opportunity to inform the future development of more effective programs and policies that protect and support all children, especially the most vulnerable.