UCSF Paul Calabresi K12 Career Development Program in Clinical Oncology

加州大学旧金山分校 Paul Calabresi K12 临床肿瘤学职业发展计划

• 批准号: 10206670
• 负责人: EMILY K BERGSLAND
• 金额: $ 5.34万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10206670
• 关键词: Advisory Committees; Area; Basic Cancer Research; Biological Markers; Biometry; Biostatistical Methods; Clinic; Clinical; Clinical Oncology; Clinical Research; Communities; Competence; Comprehensive Cancer Center; Development; Development Plans; Educational Curriculum; Educational workshop; Ensure; Environment; Epidemiologic Methods; Faculty; Family; Fostering; Funding; Goals; Grant; Health Sciences; Image; Individual; Institutes; Investigational Therapies; K-Series Research Career Programs; Laboratories; Lead; Malignant Childhood Neoplasm; Malignant Neoplasms; Medical Oncology; Mentored Clinical Scientist Development Program; Mentors; Monitor; NCI Center for Cancer Research; Patient Outcomes Assessments; Physicians; Program Development; Protocols documentation; Radiation Oncology; Research; Research Methodology; Research Personnel; Rotation; SECTM1 gene; Science; Scientist; Series; Surgical Oncology; Technology; Therapeutic Human Experimentation; Training; Training Programs; Translational Research; Ursidae Family; Work; Writing; anticancer research; base; bench to bedside; cancer clinical trial; career development; certificate program; community engagement; design; drug development; experience; health care disparity; innovation; interest; multidisciplinary; neuro-oncology; next generation; patient oriented; post-doctoral training; programs; research and development; responsible research conduct; skills; success; tool; translational cancer research

Project Summary/Abstract The goal of the UCSF Paul Calabresi Career Development Award for Clinical Oncology is to foster the development of the next generation of clinical scientists to be effective partners with discovery scientists and conduct high impact and innovative patient-centered cancer research. The Program will be housed in the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC), bringing to bear the exceptional research, clinical, and training environment of one of the world’s leading health sciences institutes. This multidisciplinary training program will leverage strengths in basic cancer research, experimental therapeutics, and clinical research methodology. Two experienced physician-scientists (one clinical researcher and one laboratory-based scientist) will direct the Program. An accomplished group of faculty will bring expertise in cancer-related clinical and translational research, imaging, patient-reported outcomes, biomarkers, healthcare disparities, community engagement, and biostatistics. Building on recent research and technology advancements and key areas for training identified in our HDFCCC strategic review, the two-year Program (which incorporates mentored research, career development guidance, and a core curriculum) is designed to facilitate completion of the year-long Advanced Training in Clinic Research certificate program in Year 1 (epidemiologic and biostatistical methods). Year 2 will focus on mentored research, professional skills, and achieving independence. An Advisory Committee (15 UCSF faculty, 6 external advisors) will work with the program directors to select up to four K12 Scholars, monitor Scholar progress, and identify opportunities for program improvement. Eligible candidates (within five years of training) will be selected from a diverse pool of UCSF faculty and well-established postdoctoral training programs in medical oncology, pediatric malignancies, neuro-oncology, radiation oncology, and surgical oncology. Each Scholar will work with at least one clinically focused and one laboratory-based mentor on their career development committee to design an individual career development plan outlining goals and tailored didactic and hands-on training experiences (including short clinical and laboratory rotations, grant-writing workshops, etc.) that will ensure competency across four core areas: (1) Clinical research methods; (2) Principles of translational cancer research and drug development; (3) Academic success skills and (4) Responsible conduct of research. New K12 program activities, including a 5-day bootcamp (Clinically Driven Discovery Science in Cancer: From the Bench to the Bedside), a seminar series (From Concept to Completion: Strategies for Successful Cancer Clinical Trials), and embedded patient-oriented cancer research experiences (e.g. scientific protocol review, presenting to the Community Advisory Board) will benefit Scholars who are directly supported by K12 funding and other UCSF faculty and trainees with an interest in clinical-translational cancer research. Upon graduation, scholars will have the tools to lead independent, rigorous, and impactful patient-centered clinical research programs.

项目总结/摘要 UCSF Paul Calabresi临床肿瘤学职业发展奖的目标是培养 培养下一代临床科学家成为发现科学家的有效合作伙伴， 开展高影响力和创新的以患者为中心的癌症研究。该计划将被安置在 UCSF海伦迪勒家庭综合癌症中心（HDFCCC），带来了特殊的 世界领先的健康科学机构之一的研究、临床和培训环境。这 多学科培训计划将利用基础癌症研究，实验治疗， 和临床研究方法。两名经验丰富的医生-科学家（一名临床研究员，一名 实验室科学家）将指导该计划。一个有成就的教师小组将带来专业知识， 癌症相关临床和转化研究、成像、患者报告结局、生物标志物、医疗保健 差异、社区参与和生物统计。以最新研究和技术为基础 在我们的HDFCCC战略审查中确定的进展和关键培训领域， （包括指导研究，职业发展指导和核心课程）旨在 促进在第一年完成为期一年的临床研究证书课程的高级培训 （流行病学和生物统计学方法）。第二年将侧重于指导研究，专业技能， 实现独立。一个咨询委员会（15 UCSF教师，6外部顾问）将与 项目主任选择最多四名K12学者，监测学者的进展，并确定机会， 方案改进。合格的候选人（培训五年内）将从不同的人才库中挑选， 加州大学旧金山分校的教职员工和肿瘤内科、儿科恶性肿瘤领域完善的博士后培训项目， 神经肿瘤学、放射肿瘤学和外科肿瘤学。每位学者将与至少一位临床医生合作 职业发展委员会中的一名专注的导师和一名基于实验室的导师， 职业发展计划概述目标和量身定制的教学和实践培训经验（包括 短期临床和实验室轮换，赠款写作讲习班等）这将确保四个方面的能力， 核心领域：（1）临床研究方法;（2）转化癌症研究和药物治疗的原则 发展;（3）学术成功技能和（4）负责任的研究行为。新K12计划 活动，包括为期5天的训练营（临床驱动的癌症发现科学：从板凳到 床边），研讨会系列（从概念到完成：成功的癌症临床试验的策略）， 和嵌入式面向患者的癌症研究经验（例如，科学方案审查，向 社区咨询委员会）将受益于K12资金和其他UCSF直接支持的学者 对临床转化癌症研究感兴趣的教师和学员。毕业后，学生将 拥有领导独立，严格和有效的以患者为中心的临床研究项目的工具。