UCSF Paul Calabresi K12 Career Development Program in Clinical Oncology

加州大学旧金山分校 Paul Calabresi K12 临床肿瘤学职业发展计划

• 批准号: 10368108
• 负责人: EMILY K BERGSLAND
• 金额: $ 42.23万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10368108
• 关键词: Advisory Committees; Area; Basic Cancer Research; Biological Markers; Biometry; Biostatistical Methods; Clinic; Clinical; Clinical Oncology; Clinical Research; Communities; Competence; Comprehensive Cancer Center; Development; Development Plans; Educational Curriculum; Educational workshop; Ensure; Environment; Epidemiologic Methods; Faculty; Family; Fostering; Funding; Goals; Grant; Health Sciences; Image; Individual; Institutes; Investigational Therapies; K-Series Research Career Programs; Laboratories; Lead; Malignant Childhood Neoplasm; Malignant Neoplasms; Medical Oncology; Mentored Clinical Scientist Development Program; Mentors; Monitor; NCI Center for Cancer Research; Patient Outcomes Assessments; Physicians; Program Development; Protocols documentation; Radiation Oncology; Research; Research Methodology; Research Personnel; Rotation; SECTM1 gene; Science; Scientist; Series; Surgical Oncology; Technology; Therapeutic Human Experimentation; Training; Training Programs; Translational Research; Ursidae Family; Work; Writing; anticancer research; base; bench to bedside; cancer clinical trial; career development; certificate program; community engagement; design; drug development; experience; health care disparity; innovation; interest; multidisciplinary; neuro-oncology; next generation; patient oriented; post-doctoral training; programs; research and development; responsible research conduct; skills; success; tool; translational cancer research

Project Summary/Abstract The goal of the UCSF Paul Calabresi Career Development Award for Clinical Oncology is to foster the development of the next generation of clinical scientists to be effective partners with discovery scientists and conduct high impact and innovative patient-centered cancer research. The Program will be housed in the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC), bringing to bear the exceptional research, clinical, and training environment of one of the world’s leading health sciences institutes. This multidisciplinary training program will leverage strengths in basic cancer research, experimental therapeutics, and clinical research methodology. Two experienced physician-scientists (one clinical researcher and one laboratory-based scientist) will direct the Program. An accomplished group of faculty will bring expertise in cancer-related clinical and translational research, imaging, patient-reported outcomes, biomarkers, healthcare disparities, community engagement, and biostatistics. Building on recent research and technology advancements and key areas for training identified in our HDFCCC strategic review, the two-year Program (which incorporates mentored research, career development guidance, and a core curriculum) is designed to facilitate completion of the year-long Advanced Training in Clinic Research certificate program in Year 1 (epidemiologic and biostatistical methods). Year 2 will focus on mentored research, professional skills, and achieving independence. An Advisory Committee (15 UCSF faculty, 6 external advisors) will work with the program directors to select up to four K12 Scholars, monitor Scholar progress, and identify opportunities for program improvement. Eligible candidates (within five years of training) will be selected from a diverse pool of UCSF faculty and well-established postdoctoral training programs in medical oncology, pediatric malignancies, neuro-oncology, radiation oncology, and surgical oncology. Each Scholar will work with at least one clinically focused and one laboratory-based mentor on their career development committee to design an individual career development plan outlining goals and tailored didactic and hands-on training experiences (including short clinical and laboratory rotations, grant-writing workshops, etc.) that will ensure competency across four core areas: (1) Clinical research methods; (2) Principles of translational cancer research and drug development; (3) Academic success skills and (4) Responsible conduct of research. New K12 program activities, including a 5-day bootcamp (Clinically Driven Discovery Science in Cancer: From the Bench to the Bedside), a seminar series (From Concept to Completion: Strategies for Successful Cancer Clinical Trials), and embedded patient-oriented cancer research experiences (e.g. scientific protocol review, presenting to the Community Advisory Board) will benefit Scholars who are directly supported by K12 funding and other UCSF faculty and trainees with an interest in clinical-translational cancer research. Upon graduation, scholars will have the tools to lead independent, rigorous, and impactful patient-centered clinical research programs.

项目摘要/摘要 加州大学洛杉矶分校保罗·卡拉布雷西临床肿瘤学职业发展奖的目标是培养 发展下一代临床科学家，使其成为发现科学家和 开展以患者为中心的高影响力和创新性的癌症研究。该计划将设在 加州大学海伦·迪勒家庭综合癌症中心(HDfccc)，带来了特殊的 世界领先的健康科学机构之一的研究、临床和培训环境。这 多学科培训计划将利用基础癌症研究、实验治疗学、 和临床研究方法。两名经验丰富的内科科学家(一名临床研究人员和一名 以实验室为基础的科学家)将指导该计划。一个经验丰富的教职员工团队将带来专业知识 与癌症相关的临床和转化性研究、成像、患者报告的结果、生物标志物、医疗保健 差异、社区参与和生物统计。以最新研究和技术为基础 在我们的HDfccc战略审查--两年计划--中确定的进展和关键培训领域 (包含指导性研究、职业发展指导和核心课程)旨在 在第一年完成为期一年的临床研究高级培训证书课程 (流行病学和生物统计学方法)。第二年将专注于有指导的研究、专业技能和 实现独立。一个咨询委员会(加州大学旧金山分校15名教职员工，6名外部顾问)将与 项目总监负责挑选最多四名K12奖学金获得者，监督奖学金获得者的进度，并寻找机会 计划改进。合格的候选人(在五年培训期间)将从不同的人才库中挑选出来 加州大学旧金山分校的教职员工和完善的博士后培训计划， 神经肿瘤学、放射肿瘤学和外科肿瘤学。每名学者将与至少一名临床医生合作 专注于他们的职业发展委员会，并由一名基于实验室的导师设计个人 职业发展计划，概述目标和量身定做的授课和实践培训经验(包括 短期临床和实验室轮换、赠款撰写讲习班等)这将确保四个方面的能力 核心领域：(1)临床研究方法；(2)转化型癌症研究和药物原理 发展；(3)学术成功技能；(4)负责任的研究行为。新的K12计划 活动，包括为期5天的训练营(临床驱动的癌症发现科学：从长凳到 床边)，系列研讨会(从概念到完成：成功的癌症临床试验的战略)， 和嵌入式面向患者的癌症研究经验(例如，科学方案审查，向 社区咨询委员会)将使K12基金和其他加州大学旧金山分校直接支持的学者受益 对临床-转化型癌症研究感兴趣的教师和实习生。毕业后，学者们将 拥有领导独立、严谨和有效的以患者为中心的临床研究计划的工具。