Core-002

核心002

• 批准号: 10206305
• 负责人: Sundeep Khosla
• 金额: $ 58.26万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-18 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10206305
• 关键词: Active Learning; Area; Arizona; Caring; Clinic; Clinical Sciences; Clinical Trials; Collaborations; Communities; Community Health Systems; Community Healthcare; E-learning; Elements; Florida; Goals; Group Practice; Health; Health Personnel; Human; Incentives; Individual; Informatics; Iowa; Laboratories; Leadership; Light; Methods; Minnesota; Mission; Participant; Patient Care; Patients; Positioning Attribute; Process; Research; Research Project Grants; Role; Science; Site; Training; Translation Process; Translational Research; Translations; Wisconsin; Work; Workforce Development; clinical center; clinical practice; community engagement; dissemination research; education research; health care delivery; health care service organization; healthcare community; implementation research; improved; informatics tool; innovation; member; multidisciplinary; patient population; programs; science education; translational pipeline

Clinical and Translational Science (CTS) has been a fundamental and highly valued element of Mayo Clinic since its founding, and Mayo Clinic’s mission “to provide the best care to every patient every day through integrated clinical practice, education, and research” has always aligned well with the NCATS mission. Mayo Clinic is an integrated academic group practice with major sites in Minnesota, Arizona, and Florida; a large community Health System (MCHS) in Minnesota, Wisconsin, and Iowa; and an affiliated national “Care Network” (MCCN). Thus, the Mayo Clinic Center for Clinical and Translational Science (CCaTS) is of national scope. MCHS and MCCN provide unique laboratories for late-stage dissemination and implementation research as well as for the conduct of high-priority clinical trials in community health care organizations. Mayo Clinic is also leading both a PCORI CDRN and a PPRN. These widespread connections, and programs that span the translational spectrum, position Mayo Clinic CCaTS to become a true “hub” for CTS. The present application builds on key accomplishments over the previous 5 years in each of the major areas relevant to the NCATS mission. Mayo CCaTS has mature, innovative programs in workforce development for all members of CTS teams and is diversifying them through online and experiential learning. Incentivizing Team Science has always been part of the institutional culture at Mayo, and we are continuing to build on that strength. Given its role, particularly in Rochester, as a major local and regional provider of health care, community engagement has also been a priority for Mayo Clinic, and a range of methods for bidirectional engagement are proposed. Advances in informatics are also enabling us to connect with new and diverse patient populations. Thus, in light of our institutional traditions and accomplishments over the past 5 years, we believe we are uniquely positioned to accomplish our Specific Aims: Aim 1. Train and maintain an outstanding multidisciplinary CTS workforce, including the entire spectrum of individuals involved in CTS; Aim 2. Eliminate barriers to the work of translation by streamlining methods and processes, including improved and innovative informatics tools, completing the transformation of Mayo’s clinical trial process, and accelerating the implementation of trial results and other discoveries to improve patient care; Aim 3. Engage and incorporate a range of diverse stakeholders as active participants in CCaTS, both in leadership roles and in specific research projects, to improve the process of translation and the delivery of health care, promoting community engagement in research among our Mayo workforce and engaging our local and national communities using both traditional and innovative approaches; and Aim 4. Expand, strengthen, and streamline our regional and national collaborations in all aspects of CTS and education, connecting with our regional and national partners, as well as with the CTSA Consortium, to achieve the ultimate goal of NCATS to improve patient care and human health.

临床和转化科学 (CTS) 一直是 Mayo Clinic 的基本且高度重视的要素 自成立以来，梅奥诊所的使命是“通过每天为每位患者提供最好的护理” 整合临床实践、教育和研究”始终与 NCATS 的使命保持一致。 梅奥诊所是一家综合学术团体诊所，主要站点位于明尼苏达州、亚利桑那州和佛罗里达州；一个 明尼苏达州、威斯康星州和爱荷华州的大型社区卫生系统 (MCHS)；以及附属的国家“关怀 网络”（MCCN）。因此，梅奥诊所临床和转化科学中心（CCaTS）是国家级的 范围。 MCHS 和 MCCN 为后期传播和实施提供独特的实验室 研究以及在社区卫生保健组织中进行高度优先的临床试验。梅奥 Clinic 还领导着 PCORI CDRN 和 PPRN。这些广泛的联系和计划 跨越翻译领域，使 Mayo Clinic CCaTS 成为真正的 CTS“中心”。 本申请建立在过去 5 年各主要领域取得的主要成就的基础上 与 NCATS 任务相关。 Mayo CCaTS 在劳动力发展方面拥有成熟、创新的计划 CTS 团队的所有成员，并通过在线和体验式学习使他们多元化。激励 团队科学一直是梅奥机构文化的一部分，我们将继续在此基础上发展 力量。鉴于其作为当地和区域主要医疗保健提供者的作用，特别是在罗彻斯特， 社区参与也是梅奥诊所的首要任务，并提供了一系列双向方法 提议参与。信息学的进步也使我们能够与新的和多样化的事物建立联系 患者人群。因此，鉴于我们的制度传统和过去 5 年取得的成就，我们 相信我们具有独特的优势来实现我们的具体目标： 目标 1. 培训和维持 优秀的多学科 CTS 员工队伍，包括参与 CTS 的所有人员； 目标 2. 通过简化方法和流程消除翻译工作的障碍，包括 改进和创新的信息学工具，完成梅奥临床试验流程的转型， 加快实施试验结果和其他发现，以改善患者护理；目的 3. 让一系列不同的利益相关者成为 CCaTS 的积极参与者，无论是在 领导角色和具体研究项目，以改进翻译过程和 提供医疗保健，促进梅奥工作人员社区参与研究，以及 使用传统和创新方法让我们的地方和国家社区参与进来；和目标 4。 扩大、加强和简化我们在 CTS 和 教育，与我们的区域和国家合作伙伴以及 CTSA 联盟建立联系， 实现 NCATS 改善患者护理和人类健康的最终目标。