Core-002

核心002

• 批准号: 10206305
• 负责人: Sundeep Khosla
• 金额: $ 58.26万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-18 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10206305
• 关键词: Active Learning; Area; Arizona; Caring; Clinic; Clinical Sciences; Clinical Trials; Collaborations; Communities; Community Health Systems; Community Healthcare; E-learning; Elements; Florida; Goals; Group Practice; Health; Health Personnel; Human; Incentives; Individual; Informatics; Iowa; Laboratories; Leadership; Light; Methods; Minnesota; Mission; Participant; Patient Care; Patients; Positioning Attribute; Process; Research; Research Project Grants; Role; Science; Site; Training; Translation Process; Translational Research; Translations; Wisconsin; Work; Workforce Development; clinical center; clinical practice; community engagement; dissemination research; education research; health care delivery; health care service organization; healthcare community; implementation research; improved; informatics tool; innovation; member; multidisciplinary; patient population; programs; science education; translational pipeline

Clinical and Translational Science (CTS) has been a fundamental and highly valued element of Mayo Clinic since its founding, and Mayo Clinic’s mission “to provide the best care to every patient every day through integrated clinical practice, education, and research” has always aligned well with the NCATS mission. Mayo Clinic is an integrated academic group practice with major sites in Minnesota, Arizona, and Florida; a large community Health System (MCHS) in Minnesota, Wisconsin, and Iowa; and an affiliated national “Care Network” (MCCN). Thus, the Mayo Clinic Center for Clinical and Translational Science (CCaTS) is of national scope. MCHS and MCCN provide unique laboratories for late-stage dissemination and implementation research as well as for the conduct of high-priority clinical trials in community health care organizations. Mayo Clinic is also leading both a PCORI CDRN and a PPRN. These widespread connections, and programs that span the translational spectrum, position Mayo Clinic CCaTS to become a true “hub” for CTS. The present application builds on key accomplishments over the previous 5 years in each of the major areas relevant to the NCATS mission. Mayo CCaTS has mature, innovative programs in workforce development for all members of CTS teams and is diversifying them through online and experiential learning. Incentivizing Team Science has always been part of the institutional culture at Mayo, and we are continuing to build on that strength. Given its role, particularly in Rochester, as a major local and regional provider of health care, community engagement has also been a priority for Mayo Clinic, and a range of methods for bidirectional engagement are proposed. Advances in informatics are also enabling us to connect with new and diverse patient populations. Thus, in light of our institutional traditions and accomplishments over the past 5 years, we believe we are uniquely positioned to accomplish our Specific Aims: Aim 1. Train and maintain an outstanding multidisciplinary CTS workforce, including the entire spectrum of individuals involved in CTS; Aim 2. Eliminate barriers to the work of translation by streamlining methods and processes, including improved and innovative informatics tools, completing the transformation of Mayo’s clinical trial process, and accelerating the implementation of trial results and other discoveries to improve patient care; Aim 3. Engage and incorporate a range of diverse stakeholders as active participants in CCaTS, both in leadership roles and in specific research projects, to improve the process of translation and the delivery of health care, promoting community engagement in research among our Mayo workforce and engaging our local and national communities using both traditional and innovative approaches; and Aim 4. Expand, strengthen, and streamline our regional and national collaborations in all aspects of CTS and education, connecting with our regional and national partners, as well as with the CTSA Consortium, to achieve the ultimate goal of NCATS to improve patient care and human health.

临床和翻译科学(CTS)一直是梅奥诊所的基础和高度重视的元素 自成立以来，梅奥诊所的使命是通过以下方式为每一位患者提供最好的护理 综合临床实践、教育和研究“一直很好地与NCATS的使命保持一致。 梅奥诊所是一家综合性学术团体诊所，在明尼苏达州、亚利桑那州和佛罗里达州拥有主要网站；a 明尼苏达州、威斯康星州和爱荷华州的大型社区卫生系统(MCHS)；以及附属的全国医疗保健 网络“(MCCN)。因此，梅奥临床和翻译科学中心(CCATS)是全国性的 作用域。MCHS和MCCN为后期传播和实施提供独特的实验室 研究以及在社区卫生保健组织中进行高优先级临床试验。蛋黄酱 诊所还领导着一个PCORI CDRN和一个PPRN。这些广泛的连接和程序 跨越翻译范围，将Mayo Clinic CCaTS定位为CTS真正的“枢纽”。 本申请建立在过去5年在每个主要领域取得的主要成就的基础上 与NCATS任务相关。梅奥CCaTS在劳动力发展方面拥有成熟、创新的计划 CTS团队的所有成员，并正在通过在线和体验式学习使他们多样化。激励 团队科学一直是梅奥机构文化的一部分，我们将继续在此基础上继续发展 力量。鉴于它的作用，特别是在罗切斯特，作为当地和区域主要的医疗保健提供者， 社区参与也是梅奥诊所的优先事项，并提供了一系列双向的方法 接洽是建议的。信息学的进步也使我们能够与新的和多样化的 患者群体。因此，根据我们过去5年的体制传统和成就，我们 相信我们在实现特定目标方面具有得天独厚的优势：目标1.培训和维护 优秀的多学科CTS工作人员，包括参与CTS的所有个人； 目标2.通过精简方法和流程消除翻译工作的障碍，包括 改进和创新的信息学工具，完成了Mayo临床试验流程的转变， 加快试验结果和其他发现的实施，以改善患者护理；目标 3.让一系列不同的利益攸关方作为CCATS的积极参与者参与进来，这两个项目都是 在具体的研究项目中发挥领导作用，以改进翻译过程和 提供医疗保健，促进我们Mayo员工和社区参与研究 利用传统和创新方法使我们的地方和国家社区参与进来；以及目标4。 扩大、加强和简化我们在CTS和CTS各个方面的区域和国家合作 教育，与我们的区域和国家合作伙伴以及CTSA联盟联系起来，以 实现NCATS改善患者护理和人类健康的最终目标。