Core-004

核心004

• 批准号: 10206307
• 负责人: Sundeep Khosla
• 金额: $ 58.26万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-18 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10206307
• 关键词: Active Learning; Area; Arizona; Caring; Clinic; Clinical Sciences; Clinical Trials; Collaborations; Communities; Community Health Systems; Community Healthcare; E-learning; Elements; Florida; Goals; Group Practice; Health; Health Personnel; Human; Incentives; Individual; Informatics; Iowa; Laboratories; Leadership; Light; Methods; Minnesota; Mission; Participant; Patient Care; Patients; Positioning Attribute; Process; Research; Research Project Grants; Role; Science; Site; Training; Translation Process; Translational Research; Translations; Wisconsin; Work; Workforce Development; clinical center; clinical practice; community engagement; dissemination research; education research; health care delivery; health care service organization; healthcare community; implementation research; improved; informatics tool; innovation; member; multidisciplinary; patient population; programs; science education; translational pipeline

Clinical and Translational Science (CTS) has been a fundamental and highly valued element of Mayo Clinic since its founding, and Mayo Clinic’s mission “to provide the best care to every patient every day through integrated clinical practice, education, and research” has always aligned well with the NCATS mission. Mayo Clinic is an integrated academic group practice with major sites in Minnesota, Arizona, and Florida; a large community Health System (MCHS) in Minnesota, Wisconsin, and Iowa; and an affiliated national “Care Network” (MCCN). Thus, the Mayo Clinic Center for Clinical and Translational Science (CCaTS) is of national scope. MCHS and MCCN provide unique laboratories for late-stage dissemination and implementation research as well as for the conduct of high-priority clinical trials in community health care organizations. Mayo Clinic is also leading both a PCORI CDRN and a PPRN. These widespread connections, and programs that span the translational spectrum, position Mayo Clinic CCaTS to become a true “hub” for CTS. The present application builds on key accomplishments over the previous 5 years in each of the major areas relevant to the NCATS mission. Mayo CCaTS has mature, innovative programs in workforce development for all members of CTS teams and is diversifying them through online and experiential learning. Incentivizing Team Science has always been part of the institutional culture at Mayo, and we are continuing to build on that strength. Given its role, particularly in Rochester, as a major local and regional provider of health care, community engagement has also been a priority for Mayo Clinic, and a range of methods for bidirectional engagement are proposed. Advances in informatics are also enabling us to connect with new and diverse patient populations. Thus, in light of our institutional traditions and accomplishments over the past 5 years, we believe we are uniquely positioned to accomplish our Specific Aims: Aim 1. Train and maintain an outstanding multidisciplinary CTS workforce, including the entire spectrum of individuals involved in CTS; Aim 2. Eliminate barriers to the work of translation by streamlining methods and processes, including improved and innovative informatics tools, completing the transformation of Mayo’s clinical trial process, and accelerating the implementation of trial results and other discoveries to improve patient care; Aim 3. Engage and incorporate a range of diverse stakeholders as active participants in CCaTS, both in leadership roles and in specific research projects, to improve the process of translation and the delivery of health care, promoting community engagement in research among our Mayo workforce and engaging our local and national communities using both traditional and innovative approaches; and Aim 4. Expand, strengthen, and streamline our regional and national collaborations in all aspects of CTS and education, connecting with our regional and national partners, as well as with the CTSA Consortium, to achieve the ultimate goal of NCATS to improve patient care and human health.

临床和转化科学（CTS）一直是马约诊所的基本且高度重视的要素 自成立以来，马约诊所的使命是"每天为每位患者提供最好的护理， "综合临床实践、教育和研究"一直与NCATS的使命保持一致。 马约诊所是一个综合的学术团体的做法，在明尼苏达州，亚利桑那州和佛罗里达的主要网站; 明尼苏达州、威斯康星州和爱荷华州的大型社区卫生系统（MCHS）;以及附属的国家"保健 网络"（MCCN）。因此，马约诊所临床和转化科学中心（CCaTS）是国家级的 scope. MCHS和MCCN为后期传播和实施提供独特的实验室 研究以及在社区卫生保健组织进行高优先级的临床试验。Mayo 诊所还领导了PCRI CDRN和PPRN。这些广泛的联系，以及 跨越平移范围，将马约诊所CCaTS定位为CTS的真正"中心"。 本应用程序建立在过去5年在每个主要领域取得的主要成就的基础上 与NCATS的使命有关。马约CCaTS在劳动力发展方面拥有成熟、创新的计划， CTS团队的所有成员，并通过在线和体验式学习使他们多样化。激励 团队科学一直是马约机构文化的一部分，我们将继续在此基础上发展 实力鉴于它的作用，特别是在罗切斯特，作为一个主要的地方和地区的医疗保健提供者， 社区参与也是马约诊所的首要任务，并采取了一系列双向方法 提出了参与。信息学的进步也使我们能够与新的和多样化的 患者人群。因此，根据我们过去五年的机构传统和成就，我们 我相信我们有独特的优势来实现我们的具体目标：目标1。训练和维护 杰出的多学科CTS员工队伍，包括参与CTS的所有个人; 目标二。通过简化方法和流程，消除翻译工作的障碍，包括 改进和创新的信息学工具，完成了马约临床试验过程的转变， 并加速实施试验结果和其他发现，以改善患者护理;目的 3.让各种不同的利益攸关方积极参与CCaTS， 领导角色和具体的研究项目，以改善翻译过程和 提供医疗保健，促进社区参与我们的马约劳动力的研究， 利用传统和创新方法使我们的地方和国家社区参与进来;目标4。 扩大、加强和简化我们在CTS各个方面的区域和国家合作， 教育，与我们的区域和国家合作伙伴以及CTSA联盟建立联系， 实现NCATS的最终目标，以改善患者护理和人类健康。