Pathways to Mentorship and Research: Training the Next Generation Physician-Scientists

项目总结 内科科学家在弥合基础科学和临床医生之间的鸿沟方面发挥着独特的作用 通过识别重要临床问题和转化结果来改善患者 关心。不幸的是，内科医生-科学家队伍继续减少，并对 生物医学研究中的负面、长期后果。许多派驻计划关注的是 注重获取医学知识，而不是培养求知欲和 生物医学研究领域的入门。在这项建议中，我们的目标是提高吸引力 在住院医师培训期间，为成为一名内科科学家做好准备。进一步推动 人们对内科科学家职业的兴趣正在减弱，那就是找出一种鼓舞人心的 也是成功的导师。迫切需要重新强调对现有医生的重视- 科学家是实习生的榜样。传染病和免疫学是基本领域 这将极大地受益于一支强大的医生-科学家队伍。马萨诸塞州 综合医院/哈佛医学院，特别是在医学部和 外科，在培训内科医生和科学家方面有着长期的记录。我们假设早些时候 纵向指导与研究发展和专业发展相结合 传染病和免疫学领域的技能将使医生和科学家成为职业 这条道路具有吸引力和可持续性。为此，我们建议实施MGH-NEXT 中的新一代医生-科学家培训路径(MGH-下一代PSTP)计划 免疫学和传染病。MGH-下一代PSTP计划的中心是 以下目标： 目标1：通过强有力的、 纵向指导，强调领导力的基本要素。 目标2：制定必要的充足的基本实验室和流行病学方法 在免疫学和传染病领域进行高质量的研究。 目标3：制定基于假设的研究问题、开发和执行 研究项目，并有效地传达其科学的意义。 这些举措旨在吸引、培训和留住生物医学领域的医学博士 在他们职业生涯最关键的关头进行调查--实习培训。

PROJECT SUMMARY Physician-scientists play a unique role in bridging the gap between basic science and clinicians through the identification of important clinical questions and translating results to improve patient care. Unfortunately, the physician-scientist workforce continues to diminish and contributes to negative, long-lasting consequences in biomedical research. Many residency programs focus heavily on acquiring medical knowledge as opposed to fostering intellectual curiosity and an introduction into the biomedical research field. In this proposal, we aim to enhance attractiveness and preparedness for a career as a physician-scientist during residency training. Furthering the diminishing interest in a career as a physician-scientist is the ability to identify an encouraging and successful mentor. There is a critical need for a renewed emphasis on established physician- scientists as role models to trainees. Infectious Disease and Immunology are fundamental areas of science that greatly benefits from a robust physician-scientist workforce. Massachusetts General Hospital/Harvard Medical School, particularly in the Departments of Medicine and Surgery, has a long track record of training physician-scientists. We hypothesize that early and longitudinal mentorship combined with development of research and professional development skills in the areas of Infectious Diseases and Immunology will make the physician-scientist career path attractive and sustainable. To this end, we propose the implementation of the MGH-Next Generation Physician-Scientist Training Pathways (MGH-Next Gen PSTP) program in Immunology and Infectious Disease. The MGH-Next Gen PSTP program is centered around the following objectives: Objective 1: Foster the creation of important scientific contributions through strong, longitudinal mentorship with an emphasis on leadership essentials. Objective 2: Develop sufficient basic laboratory and epidemiology approaches necessary to conduct high-quality research in the areas of immunology and infectious diseases. Objective 3: Formulate hypothesis-based research questions, development and execution of a research project, and effectively communicate the significance of their science. Together, these initiatives are designed to attract, train, and retain MDs in biomedical investigation at the most critical juncture of their career - residency training.