Core A. Administrative Core

项目摘要-行政核心 本申请寻求资金，以继续智力和发展研究所 残疾人研究中心（IDDRC）在加州大学戴维斯分校。IDDRC于2013年启动 并且是网络中14个IDDRC中最新的一个。管理核心（Admin Core） 领导力、资源和支持，以确保科学创新，同时加速科学成果的转化。 这些发现为碘缺乏病患者及其家庭的生活质量带来了有意义的变化。管理核心 将实现三个具体目标。目标1是支持制定和实施一项有影响力的、 缺碘症研究跨学科、转化研究议程。这一目标将通过建立一个 跨学科领导小组;建立机制，征求非洲药物滥用问题研究和咨询中心调查人员、当地和 国家网络和更广泛的科学界;监测非洲荒漠化防治中心的研究进展，包括 本申请中提出的标志性研究项目;以及创建“中心”（即，文化 跨学科合作和团队科学）。目标2：发展和保持一个强大的研究 基础设施，以支持IDDRC的转化研究议程。这一目标将通过以下方式实现： 制定获取科学核心数据的公平和有效程序; 加强科学核心;建立程序，以确保IDDRC提供高需求，成本- 有效、高质量的核心服务;以及促进获得IDDRC以外的专门知识和技术。 目标3是鼓励缺碘症研究的创新。这一目标将通过鼓励新的方案来实现， 研究和新方法的科学核心;招募新的调查员到IDDRC;并支持一个 广泛的教育活动，利用IDDRC的独特专业知识和资源， 科学家在职业生涯的各个阶段。IDDRC和行政核心的主任是伦纳德阿贝杜托， PhD.

PROJECT SUMMARY – ADMINISTRATIVE CORE The present application seeks funding to continue the MIND Institute Intellectual and Developmental Disabilities Research Center (IDDRC) at the University of California, Davis. The IDDRC was launched in 2013 and is the newest of the 14 IDDRCs in the network. The Administrative Core (Admin Core) provides the leadership, resources, and support to ensure scientific innovation while accelerating the translation of scientific discoveries into meaningful changes in quality of life for individuals with IDD and their families. The Admin Core will address three specific aims. Aim 1 is to support the development and implementation of an impactful, interdisciplinary, translational research agenda for IDD research. This aim will be addressed by creating an interdisciplinary leadership team; establishing mechanisms to solicit input from IDDRC investigators, local and national networks, and the broader scientific community; monitoring progress of IDDRC research, including the signature research project proposed in this application; and creating “centerness” (i.e., a culture of interdisciplinary collaboration and team science). Aim 2 is to develop and maintain a robust research infrastructure to support the translational research agenda of the IDDRC. This aim will be addressed by developing equitable and efficient procedures for accessing the scientific cores; securing resources to support and enhance the scientific cores; establishing procedures to ensure that the IDDRC provides high-need, cost- effective, high-quality core services; and facilitating access to expertise and technologies beyond the IDDRC. Aim 3 is to encourage innovation in IDD research. This aim will be addressed by encouraging new programs of research and new methods in the scientific cores; recruiting new investigators into the IDDRC; and supporting a broad array of educational activities that leverage the unique expertise and resources of the IDDRC and target scientists at all points in their careers. The Director of the IDDRC and Administrative Core is Leonard Abbeduto, PhD.