Core A: Administrative Core
Core A: Administrative Core
批准号:
10223992
负责人:
Warner C. Greene
金额:
$10.11万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-08-08 至 2023-07-31
关键词:
AftercareAreaBackBioinformaticsBiological MarkersBiostatistics CoreBiotechnologyBlood CellsClinicalClinical TrialsCollaborationsCommunicationCommunitiesContractsDataDecision MakingDoctor of PhilosophyEnsureExposure toFundingFutureGoalsGoldGrantHIVImmunologistImmunologyImpairmentInstitutesInstitutionInterruptionInterventionInvestigationLeadLogisticsMissionMonitorPathway interactionsPatientsPerformancePlasmaPrivatizationProcessProductivityResourcesRobin birdSamplingScheduleServicesSiteSpecimenStrategic PlanningStructureTestingTherapeuticTherapeutic InterventionTimeUnited States National Institutes of HealthVideoconferencingWorkbasecostdata exchangemeetingsmemberpredictive markerprogramssoundsuccessviral reboundvirologyvolunteerweb site
中文摘要
项目总结/文摘
英文摘要
Project Summary/Abstract
The overall success of the proposed BioMark project team depends on an efficient and highly organized
Administrative Core that effectively coordinates the team's efforts. The central mission of the proposed
BioMark project is to identify a robust set of biomarkers predicting time to rebound following treatment
interruption in HIV infected patients. This core will sek to remove or reduce the obstacles that might impair the
team from achieving its experimental goals. Keys to success are the orchestration of lively and informative
team meetings and the nucleation of the team in a manner that promotes synergistic rather than additive
scientific collaboration. The Administrative Core is organized around three specific aims: Specific Aim 1: To
provide a sound, effective administrative structure for the BioMark team that maximizes scientific productivity,
promotes free and open communication among members, allows for strategic planning on a regular basis,
ensures the implementation of sound fiscal practices to maximize resources and productivity, and promotes
the appropriate sharing, collation, and analyses of the scientific data generated. Specific Aim 2: To conduct
an annual scientific review of progress of the BioMark team by a Scientific Advisory Board comprised of three
members (beginning in year 3). Specific Aim 3: To regularly evaluate internally the performance of all
scientific projects and cores and, based on need or performance, to reallocate resources in a manner that best
serves the overall goals of the BioMark team. Dr. Warner Greene will serve as Director of this Core. This core
will be based at the Gladstone Institute of Virology and Immunology (GIVI), an institution widely recognized for
the excellence of its administrative services. Additional administrative staff participating in BioMark will include
Julia Roudabush (Gladstone Grants and Contracts) and Robin Givens (Senior Executive Assistant, Office of
the Director, GIVI). The Administrative Core will schedule biweekly videoconferences of BioMark's Executive
Committee (Greene chair, Pillai, Roan, Siliciano) alternating with videoconferencing meetings of the entire
BioMark team for review of results and discussion of future experimentation. The Executive Committee will
function as the principal decision-making body within the program. The Administrative Core will also organize
an annual strategic planning process and be responsible for launching BioMark's website to include public and
private portals, the latter facilitating data exchange among team members. In Year 3, a Scientific Advisory
Board will be assembled with plans to invite a bioinformatician, HIV immunologist, and an HIV clinical trialist to
join as members and to conduct an annual review of the entire program. The Administrative Core will also take
the lead on ensuring smooth specimen acquisition for the four different collaborating ATI trial sites and
ensuring a smooth interface between the three projects and the Bioinformatics and Biostatistics Core.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Exploring HIV-associated Neurocognitive Disorder (HAND) and HIV Latency at the Single Cell Level in Cerebral Organoids
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批准号:10237149
-
项目类别:
-
资助金额:$70.8万
-
财政年份:2019
-
负责人:Warner C. Greene
-
依托单位:
Exploring HIV-associated Neurocognitive Disorder (HAND) and HIV Latency at the Single Cell Level in Cerebral Organoids
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批准号:10006808
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项目类别:
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资助金额:$70.8万
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财政年份:2019
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负责人:Warner C. Greene
-
依托单位:
Assessing the root causes of chronic inflammation in HIV-infected individuals using drugs of abuse
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批准号:9761514
-
项目类别:
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资助金额:$71.45万
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财政年份:2017
-
负责人:Warner C. Greene
-
依托单位:
Project 2: Delineating virus and host cell-derived biomarkers predicting time to HIV rebound after treatment interruption
-
批准号:10223996
-
项目类别:
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资助金额:$76.27万
-
财政年份:2017
-
负责人:Warner C. Greene
-
依托单位:
Exploiting the Host-HIV Interface To Identify Biomarkers Predicting Time to Viral Rebound after Treatment Interruption
-
批准号:9754763
-
项目类别:
-
资助金额:$168.71万
-
财政年份:2017
-
负责人:Warner C. Greene
-
依托单位:
HIV without AIDS: A Radically Different Approach to Help the Developing World
-
批准号:9503875
-
项目类别:
-
资助金额:$16.62万
-
财政年份:2013
-
负责人:Warner C. Greene
-
依托单位:
HIV without AIDS: A Radically Different Approach to Help the Developing World
-
批准号:8606334
-
项目类别:
-
资助金额:$95.5万
-
财政年份:2013
-
负责人:Warner C. Greene
-
依托单位:
HIV without AIDS: A Radically Different Approach to Help the Developing World
-
批准号:8856536
-
项目类别:
-
资助金额:$94.07万
-
财政年份:2013
-
负责人:Warner C. Greene
-
依托单位:
HIV-Induced CD4 T-Cell Depletion: An Innate Host Defense Gone Awry?
-
批准号:8411054
-
项目类别:
-
资助金额:$32.85万
-
财政年份:2012
-
负责人:Warner C. Greene
-
依托单位:
HIV-Induced CD4 T-Cell Depletion: An Innate Host Defense Gone Awry?
-
批准号:8500196
-
项目类别:
-
资助金额:$17.64万
-
财政年份:2012
-
负责人:Warner C. Greene
-
依托单位:
Identification Novel Host Factors Regulating HIV Latency
-
批准号:8326773
-
项目类别:
-
资助金额:$42.36万
-
财政年份:2011
-
负责人:Warner C. Greene
-
依托单位:
Administrative Core
-
批准号:7684936
-
项目类别:
-
资助金额:$10.87万
-
财政年份:2009
-
负责人:Warner C. Greene
-
依托单位:
Regulation and Action of APOBEC3G
-
批准号:7846488
-
项目类别:
-
资助金额:$1.31万
-
财政年份:2009
-
负责人:Warner C. Greene
-
依托单位:
NF Kappa Beta and the Regulation of HIV Latency
-
批准号:7899482
-
项目类别:
-
资助金额:$29.28万
-
财政年份:2009
-
负责人:Warner C. Greene
-
依托单位:
Viral and Host Factors Promoting Male-to-Female Transmission of HIV
-
批准号:7684924
-
项目类别:
-
资助金额:$33.23万
-
财政年份:2009
-
负责人:Warner C. Greene
-
依托单位:
Effects of Menopause on T-cell Immunity in HIV-Infected Women
-
批准号:7555088
-
项目类别:
-
资助金额:$39.0万
-
财政年份:2008
-
负责人:Warner C. Greene
-
依托单位:
Effects of Menopause on T-cell Immunity in HIV-Infected Women
-
批准号:7690943
-
项目类别:
-
资助金额:$14.63万
-
财政年份:2008
-
负责人:Warner C. Greene
-
依托单位:
Regulation and Action of APOBEC3G
-
批准号:7083556
-
项目类别:
-
资助金额:$46.87万
-
财政年份:2005
-
负责人:Warner C. Greene
-
依托单位:
Regulation and Action of APOBEC3G
-
批准号:7005092
-
项目类别:
-
资助金额:$41.08万
-
财政年份:2005
-
负责人:Warner C. Greene
-
依托单位:
Regulation and Action of APOBEC3G
-
批准号:7414017
-
项目类别:
-
资助金额:$52.12万
-
财政年份:2005
-
负责人:Warner C. Greene
-
依托单位:
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