Placenta Association of the Americas Conference Grant

美洲胎盘协会会议拨款

• 批准号: 10226353
• 负责人: Thomas Jansson
• 金额: $ 0.88万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-03-16 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10226353
• 关键词: Address; Adult; Americas; Applications Grants; Area; Brain; Cardiovascular Diseases; Cell physiology; Cellular biology; Clinical Investigator; Complex; Development; Diabetes Mellitus; Discipline; Disease; Fertilization; Fetal Diseases; Fetal Growth Retardation; Fetal Macrosomia; Fetus; Functional disorder; Future; Goals; Grant; Health; Hour; Human; Intervention; Investigation; Life; Link; Malignant Neoplasms; Mediating; Metabolic Diseases; Molecular; Molecular Biology; Monitor; Mus; Obesity; Organ; Outcome; Pathway interactions; Placenta; Placental Biology; Play; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Public Health; Reproduction; Research; Research Personnel; Risk; Role; Scientific Inquiry; Scientist; Societies; Structure; Techniques; Technology; Time; Training; Work; career; cost; design; educational atmosphere; epidemiologic data; fetal; graduate student; in vivo; innovation; interdisciplinary approach; investigator training; lectures; meetings; multidisciplinary; novel; obstetrical complication; programs; reproductive; response; structural biology; symposium

PROJECT SUMMARY Changes in placental structure and function not only cause serious pregnancy complications but also determine life-long health by programming the fetus for future metabolic and cardiovascular disease. Unfortunately, the mechanisms linking altered placental function to poor short- and long-term outcomes are complex and remain largely unknown. To better understand placental biology and pathophysiology, a multidisciplinary approach utilizing a wide array of cutting edge technologies is required. Progress in this area is hampered by the paucity of scientific meetings focused on placental biology. The primary objective of this R13 grant proposal is to meet the urgent need of a multidisciplinary, interactive forum for dissemination of novel concepts and exchange of ideas in placental research by featuring exceptional speakers working in cutting-edge areas of research. The secondary objective is to provide a low cost, high-quality learning environment, in the area of placental biology, which will encourage attendance and active participation by a diverse group of in training and early investigators. In our conference plan we seek support for an annual one- day conference as a satellite meeting the day before the Annual Scientific Meeting of the Society of Reproductive Investigation (SRI). By this design we will maximize the impact of the meeting and will allow for attendance of a diverse group of basic scientists and clinical investigators ranging from graduate students to well established researchers. The meeting will allow ample time for interaction, informal discussion and networking and is anticipated to attract 130-150 attendees each year. The program will have a balanced mix of “state of the art” lectures presented by the leaders in the field, emerging concept presentations, and shorter talks by trainees. All speakers will be mandated to provide ample time for questions and discussion. This proposal is significant because the meeting is timely and will promote novel scientific inquiry into placental biology, which is expected to pave the way for future innovation to develop approaches to monitor placental function in vivo and to target the placenta for intervention. The proposal includes numerous innovative aspects. For example, we propose to facilitate the utilization and adaptation of emerging concepts from other research fields by inviting one speaker each year that works in a research area other than placental biology. To provide ample opportunities for early career investigators to connect, discuss, and interact with the speakers we propose to organize the conference lunch so that in training investigators will have direct access to speakers in a small group. The proposed meeting is expected to have significant and sustained impact on the field because it is unique in bringing together world-leading investigators representing diverse but complementary expertise in a creative and interactive forum, which is necessary to address the complex scientific questions pertaining to the role of placenta in determining health and disease from fetal life to adulthood.

项目概要 胎盘结构和功能的改变不仅会导致严重的妊娠并发症， 通过对胎儿未来的代谢和心血管疾病进行编程来确定终生健康。 不幸的是，将胎盘功能改变与不良短期和长期结果联系起来的机制尚不清楚。 复杂且很大程度上仍然未知。为了更好地了解胎盘生物学和病理生理学， 需要利用多种尖端技术的多学科方法。该领域的进展 由于缺乏关注胎盘生物学的科学会议而受到阻碍。此举的首要目标 R13 拨款提案是为了满足多学科、互动论坛的迫切需要，以传播 胎盘研究中的新颖概念和思想交流，由从事胎盘研究的杰出演讲者担任 前沿研究领域。第二个目标是提供低成本、高质量的学习 环境，在胎盘生物学领域，这将鼓励参加和积极参与 不同的培训和早期研究人员群体。在我们的会议计划中，我们寻求支持一年一度的活动 日会议作为学会年度科学会议前一天的卫星会议 生殖调查（SRI）。通过这种设计，我们将最大限度地发挥会议的影响力，并允许 出席的有不同群体的基础科学家和临床研究人员，从研究生到 成熟的研究人员。会议将留出充足的时间进行互动、非正式讨论和 预计每年将吸引 130-150 名与会者。该计划将均衡地组合 由该领域的领导者进行的“最先进”讲座、新兴概念演示以及更短的演讲 学员讲话。所有发言者都必须提供充足的时间来提问和讨论。这 该提案意义重大，因为这次会议很及时，并将促进对胎盘的新颖科学探究 生物学，预计将为未来开发胎盘监测方法的创新铺平道路 体内功能并针对胎盘进行干预。该提案包括众多创新 方面。例如，我们建议促进其他领域新兴概念的利用和改编 研究领域，每年邀请一位从事胎盘生物学以外研究领域工作的演讲者。到 为早期职业调查人员提供充足的机会与演讲者联系、讨论和互动 我们建议组织会议午餐，以便调查员在培训时能够直接接触到 小组中的发言者。预计拟议的会议将对 领域，因为它的独特之处在于汇集了代表不同但不同的世界领先的研究人员 在创意和互动论坛中补充专业知识，这是解决复杂问题所必需的 有关胎盘在决定从胎儿生命到疾病的健康和疾病方面的作用的科学问题 成年期。