Symposium on Obesity and Kidney Transplantation

肥胖与肾脏移植研讨会

• 批准号: 10228360
• 负责人: Heather Marie Gardiner
• 金额: $ 5万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2022-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10228360
• 关键词: Symposium; Obesity; Kidney; Transplantation

Nearly one-third of American adults are obese, defined by a body mass index (BMI) > 30 kg/m, including 38% of patients with end-stage renal disease awaiting kidney transplant in the United States. Of the over 95,000 patients currently wait listed for kidney transplant, 24% meet the criteria for class 1 obesity (defined as BMI of 30 to < 35 kg/m2) and over 14% meet the criteria for classes 2 or 3 obesity (defined as BMI of 35 to < 40 kg/m2 and  40, respectively). Among the many factors taken into consideration during the medical evaluation for kidney transplantation, patient weight often measured by BMI, has emerged as increasingly relevant with many kidney transplant programs defining maximum BMI limits and delaying or denying transplant until weight loss has been achieved. However, there is currently no consensus or standard of practice surrounding kidney transplantation for patients with varying levels of obesity. We propose a Symposium on Obesity and Kidney Transplantation, to convene a multidisciplinary group of clinicians, researchers and allied health professionals (i.e., social workers, nutritionists, dieticians) in the fields of kidney transplantation and obesity as well as patients with obesity awaiting kidney transplantation. The symposium will provide a forum for open discussion of research findings and current practice, with the goal of establishing an agenda for future research at the intersection of these fields. The symposium aims to: 1) elicit patient perspectives on and experiences with regarding the challenges and successes of weight loss and management in preparation for kidney transplantation; 2) provide a forum for sharing research findings and clinical experience related to the intersection of obesity and kidney transplantation; 3) generate a research agenda, including specific research questions, to investigate issues related to obesity and kidney transplantation; and, 4) develop a position statement and manuscript from the symposium discussions and extant literature. We propose to organize, advertise, implement and evaluate the symposium, and disseminate the resulting content. Additionally, we will engage a diverse group of clinicians and researchers in transplantation, obesity, and nutrition, to form a Steering Committee to assist in the planning, execution, evaluation and dissemination of the symposium. In addition, patients with end-stage renal disease who have been evaluated and waitlisted for kidney transplantation and who concurrently suffer from obesity that is delaying transplantation will be recruited as patient partners. Three partnering patients will serve as members of the Steering Committee and will be involved in the planning, implementation, evaluation and dissemination of the symposium. Three additional partnering patients will serve as symposium panelists and will share personal experience with weight loss as a transplant candidate to an audience of clinicians, researchers and allied health professionals. Our anticipated outcomes include an agenda for future research at the intersection of transplantation and obesity, as well as publishing a position statement and manuscript reporting the symposium content.

近三分之一的美国成年人肥胖，定义为身体质量指数（BMI）> 30 kg/m，其中38% 在美国等待肾移植的终末期肾病患者中。在超过95，000名 在目前等待肾移植的患者中，24%符合1级肥胖标准（定义为BMI < 30至< 35 kg/m2），超过14%的人符合2级或3级肥胖标准（定义为BMI为35至< 40 kg/m2 #21440;的）。在医疗评估过程中考虑的许多因素中， 肾移植，患者体重通常由BMI测量，已经成为越来越多的相关与许多 肾移植计划定义最大BMI限制，并延迟或拒绝移植，直到体重减轻 办妥了一批多年然而，目前围绕肾脏没有共识或实践标准。 不同程度肥胖患者的移植。我们提议召开肥胖与肾脏研讨会 移植，召集一个多学科小组的临床医生，研究人员和专职医疗人员 (i.e.,社会工作者、营养学家、营养学家）在肾移植和肥胖症领域以及 等待肾移植的肥胖患者。研讨会将提供一个公开讨论的论坛 研究结果和现行做法，目的是为联合国系统今后的研究制定一个议程， 这些领域的交集。研讨会的目的是：1）引起病人的观点和经验， 关于在肾脏移植准备中减肥和管理的挑战和成功 2）提供一个论坛，分享与移植相关的研究成果和临床经验， 肥胖和肾移植的交叉点; 3）制定研究议程，包括具体研究 问题，调查与肥胖和肾移植有关的问题;以及，4）制定立场 来自研讨会讨论和现存文献的声明和手稿。我们建议组织， 宣传、举办和评估研讨会，并传播研讨会的成果。此外，我们将 让不同的临床医生和研究人员参与移植，肥胖和营养，以形成一个 指导委员会协助规划、执行、评价和宣传专题讨论会。在 此外，已接受肾脏评估和等待治疗的终末期肾病患者 同时患有延迟移植的肥胖症的患者将被招募为 耐心的伙伴三名合作患者将担任指导委员会成员， 参与专题讨论会的规划、执行、评价和宣传。三个附加 合作的病人将担任专题讨论小组成员，并将分享个人经验，减肥作为一个 移植候选人的观众的临床医生，研究人员和专职医疗人员。我们预期将面临 结果包括移植和肥胖交叉点的未来研究议程，以及 发表立场声明和报告研讨会内容的稿件。