Symposium on Obesity and Kidney Transplantation

肥胖与肾脏移植研讨会

• 批准号: 10228360
• 负责人: Heather Marie Gardiner
• 金额: $ 5万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2022-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10228360
• 关键词: Symposium; Obesity; Kidney; Transplantation

Nearly one-third of American adults are obese, defined by a body mass index (BMI) > 30 kg/m, including 38% of patients with end-stage renal disease awaiting kidney transplant in the United States. Of the over 95,000 patients currently wait listed for kidney transplant, 24% meet the criteria for class 1 obesity (defined as BMI of 30 to < 35 kg/m2) and over 14% meet the criteria for classes 2 or 3 obesity (defined as BMI of 35 to < 40 kg/m2 and  40, respectively). Among the many factors taken into consideration during the medical evaluation for kidney transplantation, patient weight often measured by BMI, has emerged as increasingly relevant with many kidney transplant programs defining maximum BMI limits and delaying or denying transplant until weight loss has been achieved. However, there is currently no consensus or standard of practice surrounding kidney transplantation for patients with varying levels of obesity. We propose a Symposium on Obesity and Kidney Transplantation, to convene a multidisciplinary group of clinicians, researchers and allied health professionals (i.e., social workers, nutritionists, dieticians) in the fields of kidney transplantation and obesity as well as patients with obesity awaiting kidney transplantation. The symposium will provide a forum for open discussion of research findings and current practice, with the goal of establishing an agenda for future research at the intersection of these fields. The symposium aims to: 1) elicit patient perspectives on and experiences with regarding the challenges and successes of weight loss and management in preparation for kidney transplantation; 2) provide a forum for sharing research findings and clinical experience related to the intersection of obesity and kidney transplantation; 3) generate a research agenda, including specific research questions, to investigate issues related to obesity and kidney transplantation; and, 4) develop a position statement and manuscript from the symposium discussions and extant literature. We propose to organize, advertise, implement and evaluate the symposium, and disseminate the resulting content. Additionally, we will engage a diverse group of clinicians and researchers in transplantation, obesity, and nutrition, to form a Steering Committee to assist in the planning, execution, evaluation and dissemination of the symposium. In addition, patients with end-stage renal disease who have been evaluated and waitlisted for kidney transplantation and who concurrently suffer from obesity that is delaying transplantation will be recruited as patient partners. Three partnering patients will serve as members of the Steering Committee and will be involved in the planning, implementation, evaluation and dissemination of the symposium. Three additional partnering patients will serve as symposium panelists and will share personal experience with weight loss as a transplant candidate to an audience of clinicians, researchers and allied health professionals. Our anticipated outcomes include an agenda for future research at the intersection of transplantation and obesity, as well as publishing a position statement and manuscript reporting the symposium content.

近三分之一的美国成年人肥胖，以体重指数(BMI；30公斤/米)为标准，其中38%的人肥胖 在美国，等待肾脏移植的终末期肾病患者的比例。在超过95,000人中 目前等待肾移植的患者中，24%符合一级肥胖标准(定义为体重指数 30到35公斤/平方米)，超过14%的人符合2级或3级肥胖标准(定义为35到40公斤/平方米) 和40)。在医疗评估过程中考虑的众多因素中 肾移植，通常以体重指数来衡量患者的体重，已经变得越来越与许多人相关。 肾移植计划定义了最大BMI限制，并推迟或拒绝移植，直到体重减轻 已经实现了。然而，目前还没有关于肾脏的共识或实践标准。 移植适用于不同程度肥胖的患者。我们提议召开一个肥胖与肾脏的研讨会 移植，召集一个由临床医生、研究人员和相关卫生专业人员组成的多学科小组 (即社会工作者、营养学家、营养师)在肾移植和肥胖领域以及 等待肾移植的肥胖患者。研讨会将提供一个公开讨论的论坛。 研究结果和当前做法，目的是为今后的研究制定议程 这些领域的交集。研讨会的目的是：1)征求患者的观点和经验 关于肾脏准备中减肥和管理的挑战和成功 提供一个论坛，分享与移植有关的研究成果和临床经验 肥胖和肾移植的交集；3)制定研究议程，包括具体研究 问题，调查与肥胖和肾移植有关的问题；以及，4)发展一个职位 研讨会讨论和现存文献中的陈述和手稿。我们建议组织， 宣传、实施和评估研讨会，并传播由此产生的内容。此外，我们还将 让不同的临床医生和研究人员参与移植、肥胖和营养方面的研究，形成一个 指导委员会协助规划、执行、评估和传播专题讨论会。在……里面 此外，已接受肾脏评估和等待肾脏移植的终末期肾病患者 移植和同时患有肥胖延迟移植的人将被招募为 有耐心的搭档。三名伙伴患者将担任指导委员会成员，并将 参与研讨会的规划、实施、评估和传播。另外三个 合作患者将担任研讨会的小组成员，并将作为一名 面向临床医生、研究人员和专职卫生专业人员的移植候选人。我们期待的 结果包括未来移植和肥胖交叉研究的议程，以及 发表立场声明和汇报座谈会内容的稿件。