Administrative Core

项目摘要：管理核心 行政核心将支持卓越的研究、科学创新和 华盛顿大学参与者参与和癌症基因组学中的跨学科学术研究 测序(WU-PE-CGS)中心和NCI PE-CGS研究网络的其他成员 中心和协调中心。行政核心将实施矩阵式行政管理 结构，以培养优秀的管理和沟通。三个工作的带头人和共同带头人 该中心的单位将组成领导委员会，该委员会(与患者权益倡导者一起)将使用 参与并保持重要个人的创造力和领导力的协作过程 参与中心的团队专业知识。行政核心的目标是为 有效和高效地运行和维护WU-PE-CGS中心，以符合NIH和 大学指导方针，同时利用创新机会推动参与者参与领域 和癌症基因组学。核心将通过以下方式支持WU-PE-CGS的总体任务 目标：(1)组织所有WU-PE-CGS部门的运营结构和科学领导，并 提供监督以最大限度地提高效率、效力和责任；(2)为以下目标建立参与者参与度 服务不足/研究不足的人群通过在 网络中的其他中心以及与患者倡导团体的合作；(3)提供科学领导 在少数群体和服务不足的参与者的参与下，以及在基因组测序方面 网络；(4)评估所有WU-PE-CGS活动，并提供反馈以完善正在进行的活动；(5)建立 监测进展和协调努力的时间表和里程碑。行政核心将把 WU-PE-CGS，以优化参与者参与度研究和 罕见的、研究不足的癌症的基因组特征。WU-PE-CGS调查人员有大量 在开展协作、跨学科科学，包括研究方面的专业知识和经过证明的记录 以及在癌症控制、基因组测序、向其他利益相关者传播研究结果等方面的计划，以及 为在多个环境中工作的从业者翻译结果。我们得天独厚的地理位置为您提供科学的 领导联系和扩大关注癌症的参与者参与研究人员的网络；支持 创新；以及提高罕见和未被充分研究的癌症的基因组测序能力 与患者倡导团体和患者互动，以返回结果和持续的参与者参与。 管理核心是该中心整体科学计划和基础设施的关键要素 并为学术卓越、研究协同和效率以及临床和 中心在五年初始资助期内及之后对社区的影响

Project Summary: Administrative Core The Administrative Core will support an environment of research excellence, scientific innovation, and transdisciplinary scholarship within the Washington University Participant Engagement and Cancer Genomic Sequencing (WU-PE-CGS) Center and among other members of the NCI PE-CGS network of research centers and the coordinating center. The Administrative Core will implement a matrix-style administrative structure to foster excellence in management and communication. Leaders and co-leaders of the three working units in the Center will form the Leadership Committee, which (together with patient advocates) will use a collaborative process to engage and maintain the creativity and leadership of the significant individual and team expertise involved in the Center. The goal of the Administrative Core is to provide the structure for effective and efficient operation and maintenance of the WU-PE-CGS center in compliance with NIH and University guidelines, while leveraging innovative opportunities to advance the field of participant engagement and cancer genomics. The Core will support the overall mission of the WU-PE-CGS through the following aims: (1) Organize the operational structure and scientific leadership for all WU-PE-CGS components and provide oversight to maximize efficiency, effectiveness, and accountability; (2) Build participant engagement for underserved/understudied populations to engage in network-driven collaborative studies via outreach among other Centers in the network and collaboration with patient advocacy groups; (3) Provide scientific leadership in minority and underserved participant engagement and in genome sequencing among other scientists in the network; (4) Evaluate all WU-PE-CGS activities and provide feedback to refine ongoing activities; (5) Establish a timeline and milestones to monitor progress and coordinate efforts. The administrative core will position the WU-PE-CGS to optimize the innovation, pace, and impact of participant engagement research and genomic characterization of rare, understudied cancers. The WU-PE-CGS investigators have substantial expertise and proven track records in conducting collaborative, transdisciplinary science, including research and programs in cancer control, genome sequencing, dissemination of findings to other stakeholders, and translating results for practitioners working in multiple settings. We are uniquely situated to provide scientific leadership to connect and expand a network of cancer-focused participant engagement researchers; support innovation; and enhance capacity for genome sequencing of rare and understudied cancers and directly interact with patient advocacy groups and patients for return of results and ongoing participant engagement. The Administrative Core is a critical element of the overall scientific program and infrastructure for the Center and provides a strong foundation for scholarly excellence, research synergy and efficiency, and clinical and community impact of the Center during and beyond the five-year initial funding period