Core C: Biostatistical and Bioinformatics Core

核心 C：生物统计和生物信息学核心

• 批准号: 10708578
• 负责人: GRAHAM A. COLDITZ
• 金额: $ 22.59万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-28 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708578
• 关键词: Adverse event; Bioinformatics; Biometry; Cancer Center; Clinical Cancer Center; Clinical Trials; Collaborations; Computing Methodologies; Consult; Consultations; Data; Data Analyses; Data Collection; Data Set; Databases; Development; Ensure; Genomics; High Performance Computing; Malignant neoplasm of pancreas; Output; Pancreas; Quality Control; Reporting; Reproducibility; Research; Research Design; Research Personnel; Resource Sharing; Role; Statistical Methods; Statistical Study; System; Tissue Sample; Training; Universities; Visualization; Washington; Work; anticancer research; bioinformatics pipeline; bioinformatics tool; career; data integration; data management; data sharing; design; epidemiology study; experience; genomic data; laboratory experiment; medical schools; meetings; member; multidimensional data; programs

PROJECT SUMMARY The Biostatistics and Bioinformatics Core (Core C) facility will provide study design, pipeline development, data management, and computational support for all SPORE in Pancreas investigators and projects. The Biostatistics component of the Core will perform consultation and collaboration on all aspects of statistical study design, database development and quality control, and data analysis and interpretation. The Bioinformatics component of the Core will perform consultation and collaboration on all aspects of genomics and bioinformatics study design, pipeline development, omics data integration, visualization, interpretation and genomic data sharing through controlled access systems. Core C will provide bioinformatics and biostatistics collaborations for SPORE projects, Developmental Research Program (DRP) studies, and other Cores to ensure that robust statistical methods and robust reproducible omics analyses are available to support SPORE investigators. Core C will also provide bioinformatics and biostatistical support and training to junior investigators through the Career Enhancement Program (CEP). The Biostatistics and Bioinformatics components of Core C will work together closely to ensure their efforts are integrated and complementary.

项目摘要 生物统计学和生物信息学核心（核心C）设施将提供研究设计，管道开发，数据 管理和计算支持所有SPORE in Pancreas研究者和项目。生物统计 核心的组成部分将在统计研究设计的各个方面进行咨询和合作， 数据库开发和质量控制，以及数据分析和解释。生物信息学部分 该中心将在基因组学和生物信息学研究的各个方面进行咨询和合作 设计、管道开发、组学数据集成、可视化、解释和基因组数据共享 通过控制访问系统。Core C将为SPORE提供生物信息学和生物统计学合作 项目，发展研究计划（DRP）研究和其他核心，以确保强大的统计 方法和可靠的可重复组学分析可用于支持SPORE研究者。核心C也将 通过职业生涯为初级研究者提供生物信息学和生物统计学支持和培训 增强方案。核心C的生物统计学和生物信息学组件将一起工作 密切合作，以确保其努力是一体化和互补的。