Core C: Biostatistical and Bioinformatics Core

核心 C：生物统计和生物信息学核心

• 批准号: 10708578
• 负责人: GRAHAM A. COLDITZ
• 金额: $ 22.59万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-28 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708578
• 关键词: Adverse event; Bioinformatics; Biometry; Cancer Center; Clinical Cancer Center; Clinical Trials; Collaborations; Computing Methodologies; Consult; Consultations; Data; Data Analyses; Data Collection; Data Set; Databases; Development; Ensure; Genomics; High Performance Computing; Malignant neoplasm of pancreas; Output; Pancreas; Quality Control; Reporting; Reproducibility; Research; Research Design; Research Personnel; Resource Sharing; Role; Statistical Methods; Statistical Study; System; Tissue Sample; Training; Universities; Visualization; Washington; Work; anticancer research; bioinformatics pipeline; bioinformatics tool; career; data integration; data management; data sharing; design; epidemiology study; experience; genomic data; laboratory experiment; medical schools; meetings; member; multidimensional data; programs

PROJECT SUMMARY The Biostatistics and Bioinformatics Core (Core C) facility will provide study design, pipeline development, data management, and computational support for all SPORE in Pancreas investigators and projects. The Biostatistics component of the Core will perform consultation and collaboration on all aspects of statistical study design, database development and quality control, and data analysis and interpretation. The Bioinformatics component of the Core will perform consultation and collaboration on all aspects of genomics and bioinformatics study design, pipeline development, omics data integration, visualization, interpretation and genomic data sharing through controlled access systems. Core C will provide bioinformatics and biostatistics collaborations for SPORE projects, Developmental Research Program (DRP) studies, and other Cores to ensure that robust statistical methods and robust reproducible omics analyses are available to support SPORE investigators. Core C will also provide bioinformatics and biostatistical support and training to junior investigators through the Career Enhancement Program (CEP). The Biostatistics and Bioinformatics components of Core C will work together closely to ensure their efforts are integrated and complementary.

项目总结 生物统计和生物信息学核心(核心C)设施将提供研究设计、管道开发、数据 为胰腺研究人员和项目中的所有孢子提供管理和计算支持。生物统计学 核心部分将就统计研究设计的所有方面进行咨询和协作， 数据库开发和质量控制，以及数据分析和解释。生物信息学组成部分 将就基因组学和生物信息学研究的各个方面进行咨询和合作 设计、管道开发、组学数据集成、可视化、解释和基因组数据共享 通过受控访问系统。核心C将为孢子提供生物信息学和生物统计学合作 项目、发展研究计划(DRP)研究和其他核心，以确保可靠的统计 方法和可靠的重复性组学分析可用于支持孢子调查人员。核心C也将 在整个职业生涯中为初级调查人员提供生物信息学和生物统计学支持和培训 增强计划(CEP)。Core C的生物统计学和生物信息学组件将协同工作 密切合作，以确保它们的努力相互融合和相辅相成。