THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANT

西奈山伊坎医学院TISCH癌症研究所 主要研究者/主任：Ramon Parsons，MD，PhD 摘要：Tisch癌症研究所的使命是促进癌症的基础、临床和人群健康 研究，以预防健康个体的癌症，改善癌症患者及其家人的生活 in our diverse多样化communities社区.为了完成这一使命，TCI制定了合作研究计划 努力将发现转化为新的疗法，并制定新的预防和提供战略， 优先考虑影响我们服务范围的癌症。TCI的四个癌症研究项目是：癌症 免疫学，癌症机制，癌症预防和控制，癌症临床研究。在其 四个项目，TCI有一个强大的癌症研究基础，直接与癌症相关的资金， 53106982美元这包括36，910，750美元的同行评审资金，其中27，662，959美元是NIH资金， 其中包括来自NCI的15,939,357美元。TCI通过以下方式促进项目内和项目间的癌症研究： 战略规划、试点项目奖励、跨学科会议和务虚会以及针对具体疾病的重点 组此外，TCI通过提供出色的核心、设备和设施， 和信息化TCI支持以下五种共享资源：流式细胞术，小鼠遗传学， 显微镜，生物统计学和人类免疫监测中心，以及以下三个核心- 开发：生物储存库和病理学核心，下一代测序的生物信息学，以及 生物医学数据科学与信息学。癌症临床试验办公室及其新成立的早期 阶段试验部门提供基础设施，以执行由TCI开发的研究者发起的新方案 investigators. TCI的集水区包括东哈莱姆的纽约市（NYC）社区， 中哈莱姆和上东区，哈莱姆经历了过度的癌症发病率，发病率和 死亡率与纽约市和美国相比。此外，TCI还是世界贸易组织的协调中心。 中心第一反应计划，和救援人员受到9/11袭击形成了一个鲜明的和独特的 TCI集水区的组成部分。TCI发展和培养一支充满活力的科学家团队， 研究人员和管理人员，并提供所需的研究基础设施支持，以刺激新的癌症 这些发现和改善癌症患者及其家人的结果。

TISCH CANCER INSTITUTE AT THE ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Principal Investigator/Director: Ramon Parsons, MD, PhD ABSTRACT: The mission of the Tisch Cancer Institute is to advance basic, clinical and population health cancer research, so as to prevent cancer in healthy individuals and improve the lives of cancer patients and their families in our diverse communities. To accomplish this mission, the TCI has developed collaborative research programs that strive to translate discoveries to new therapies and to develop new prevention and delivery strategies with priority given to cancers affecting our catchment area. TCI’s four cancer research programs are: Cancer Immunology, Cancer Mechanisms, Cancer Prevention and Control, and Cancer Clinical Investigation. Within its four programs, the TCI has a strong foundation of cancer research with direct cancer-related funding of $53,106,982. This includes peer-reviewed funding of $36,910,750, of which $27,662,959 is NIH funding, including $15,939,357 from the NCI. The TCI fosters intra and inter-programmatic cancer research through strategic planning, pilot project awards, interdisciplinary meetings and retreats, and disease-specific focus groups. In addition, the TCI enables cutting-edge research by providing outstanding cores, equipment, facilities and information technology. TCI supports the following five shared resources: Flow Cytometry, Mouse Genetics, Microscopy, Biostatistics, and Human Immune Monitoring Center, as well as the following three cores-in- development: Biorepository and Pathology Core, Bioinformatics for Next Generation Sequencing, and Biomedical Data Science and Informatics. The Cancer Clinical Trials Office with its newly established Early Phase Trials Unit provides the infrastructure to conduct novel, investigator initiated protocols developed by TCI investigators. The TCI’s catchment area includes the New York City (NYC) neighborhoods of East Harlem, Central Harlem and the Upper East Side, with the Harlems experiencing excess cancer incidence, morbidity and mortality as compared to NYC and the US. In addition, the TCI is the coordinating center for the World Trade Center First Responders Program, and the rescue workers affected by the 9/11 attacks form a distinct and unique component of the TCI catchment area. TCI develops and fosters a dynamic team of scientists, clinical investigators and administrators and provides the research infrastructure support needed to spur new cancer discoveries and improve the outcomes of cancer patients and their families.