THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANT

蒂施癌症研究所 - 癌症中心支持拨款

基本信息

批准号：
10454159
负责人：
Ramon E Parsons
金额：
$ 263.84万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-01 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10454159
关键词：
Academic Medical Centers Access to Information Administrator Affect Award Bioinformatics Biometry Cancer Burden Cancer Center Support Grant Cancer Control Cancer Patient Cancer Research Project Caring Catchment Area Clinical Clinical Investigator Clinical Trials Communities Community Networks Development Disease Doctor of Philosophy Equipment Faculty Family Flow Cytometry Shared Resource Focus Groups Fostering Foundations Funding Health Personnel Human Immunologic Monitoring Incidence Individual Informatics Information Technology Infrastructure Institutes Leadership Malignant Neoplasms Microscopy Mission Morbidity - disease rate Neighborhoods New York City Pathology Patients Peer Review Pilot Projects Prevention Principal Investigator Protocols documentation Research Research Infrastructure Research Personnel Scientist Side Site Strategic Planning Students Training and Education Translating Translations United States National Institutes of Health Work anticancer research biobank biomedical data science cancer clinical trial cancer prevention cancer risk cancer therapy cancer type clinical investigation design early phase trial experience first responder improved improved outcome innovation medical schools meetings mortality mouse genetics next generation sequencing novel novel therapeutics population health prevent programs public health relevance screening training opportunity tumor immunology

项目摘要

TISCH CANCER INSTITUTE AT THE ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Principal Investigator/Director: Ramon Parsons, MD, PhD ABSTRACT: The mission of the Tisch Cancer Institute is to advance basic, clinical and population health cancer research, so as to prevent cancer in healthy individuals and improve the lives of cancer patients and their families in our diverse communities. To accomplish this mission, the TCI has developed collaborative research programs that strive to translate discoveries to new therapies and to develop new prevention and delivery strategies with priority given to cancers affecting our catchment area. TCI’s four cancer research programs are: Cancer Immunology, Cancer Mechanisms, Cancer Prevention and Control, and Cancer Clinical Investigation. Within its four programs, the TCI has a strong foundation of cancer research with direct cancer-related funding of $53,106,982. This includes peer-reviewed funding of $36,910,750, of which $27,662,959 is NIH funding, including $15,939,357 from the NCI. The TCI fosters intra and inter-programmatic cancer research through strategic planning, pilot project awards, interdisciplinary meetings and retreats, and disease-specific focus groups. In addition, the TCI enables cutting-edge research by providing outstanding cores, equipment, facilities and information technology. TCI supports the following five shared resources: Flow Cytometry, Mouse Genetics, Microscopy, Biostatistics, and Human Immune Monitoring Center, as well as the following three cores-in- development: Biorepository and Pathology Core, Bioinformatics for Next Generation Sequencing, and Biomedical Data Science and Informatics. The Cancer Clinical Trials Office with its newly established Early Phase Trials Unit provides the infrastructure to conduct novel, investigator initiated protocols developed by TCI investigators. The TCI’s catchment area includes the New York City (NYC) neighborhoods of East Harlem, Central Harlem and the Upper East Side, with the Harlems experiencing excess cancer incidence, morbidity and mortality as compared to NYC and the US. In addition, the TCI is the coordinating center for the World Trade Center First Responders Program, and the rescue workers affected by the 9/11 attacks form a distinct and unique component of the TCI catchment area. TCI develops and fosters a dynamic team of scientists, clinical investigators and administrators and provides the research infrastructure support needed to spur new cancer discoveries and improve the outcomes of cancer patients and their families.

西奈山的伊坎医学院的蒂奇癌症研究所首席研究员/董事：Ramon Parsons，医学博士，博士摘要：Tisch Cancer Institute的任务是进步基本，临床和人口健康癌症研究，以预防健康个体的癌症并改善癌症患者及其家人的生活在我们的潜水员社区中。为了完成这项任务，TCI开发了协作研究计划努力将发现转化为新疗法，并通过优先考虑影响我们集水区的癌症。 TCI的四个癌症研究计划是：癌症免疫学，癌症机制，癌症预防和控制以及癌症临床研究。内部四个计划，TCI具有巨大的癌症研究基础，直接与癌症相关的资金 $ 53,106,982。这包括经同行评审的资金36,910,750美元，其中27,662,959美元是NIH资金，包括NCI的$ 15,939,357。 TCI通过战略规划，试点项目奖，跨学科会议和务虚会以及特定于疾病的重点组。此外，TCI通过提供出色的核心，设备，设施来实现尖端研究和信息技术。 TCI支持以下五个共享资源：流式细胞仪，鼠标遗传学，显微镜，生物统计学和人类免疫监测中心，以及以下三个核心开发：生物疗法和病理核心，下一代测序的生物信息学，以及生物医学数据科学和信息学。癌症临床试验办公室及其新成立阶段试验单元提供了进行新颖的基础架构，研究人员启动了由TCI开发的协议调查人员。 TCI的集水区包括纽约市（纽约市东哈林市）哈林中部和上东区，哈林人经历了超过癌症事件，发病率和与纽约市和美国相比，死亡率。此外，TCI是世界贸易协调中心中心第一响应者计划，以及受9/11攻击影响的救援人员形成了独特而独特的 TCI集水区的组成部分。 TCI的发展并培养了一个动态的科学家团队，临床调查人员和管理人员，并提供刺激新癌症所需的研究基础设施支持发现并改善癌症患者及其家人的结果。