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中文摘要
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摘要/摘要 波士顿 OAIC REC 的总体目标是培养未来的独立研究科学家 将疾病和残疾的基本机制转化为新颖的知识和技能 随着年龄的增长,可以改善人们的健康、身体机能和福祉的干预措施。 REC 将通过从以下国家选出最有前途的早期职业(Pre-K 奖)科学家来实现这一目标: 临床和基础科学学科,并为他们提供集体和个人 教育活动、研究经验、指导和职业指导,使他们能够 获得未来的职业发展或研究奖项,并最终成为转化领域的领导者 致力于发现功能促进疗法(FPT)的研究。 REC 的具体目标 如下: 1. 从不同的临床和基础科学学科中选择至少6名有才华的早期研究者 他们有很大潜力成为致力于转化研究的独立研究者。 2. 为这些学员提供为期两年的指导研究经验,重点关注 开发针对年龄增长的功能促进疗法。 3. 通过研究研讨会加强对学员相关课程领域的教育 以及关于科学和科学多样性重要性的讲座、正式课程和专门培训 保护人类和/或动物受试者。 在拟议的 5 年资助期结束时,我们将选择并培训至少 6 名 衰老领域有前途的新研究人员。这些早期研究人员将获得 生成和测试新假设所需的数据、研究经验和指导 关于 FPT 并成功为其未来研究争取独立资助。这些 个人将通过未来的领导者来丰富国家的劳动力,他们将继续开发新的 促进老年身体机能并培训后代研究人员的干预措施 继续围绕这一重要主题开展重要工作。
英文摘要
SUMMARY / ABSTRACT The overall goal of the Boston OAIC REC is to train future independent research scientists who have the knowledge and skills to translate fundamental mechanisms of disease and disability into novel interventions that can improve the health, physical function, and well-being of people as they age. The REC will achieve this by selecting the most promising early career (Pre-K Award) scientists from clinical and basic science disciplines, and providing them with both collective and individual educational activities, research experiences, mentoring, and career guidance that will enable them to acquire future career development or research awards and ultimately become leaders in translational research devoted to the discovery of function promoting therapies (FPTs). The REC’s specific aims are as follows: 1. To select at least 6 talented early investigators from diverse clinical and basic science disciplines who have strong potential to become independent investigators devoted to translational research. 2. To provide these trainees with two-year mentored research experiences focused on the development of function-promoting therapies for people as they age. 3. To enhance the education of these trainees in relevant curricular areas through research seminars and lectures, formal coursework, and specific training in the importance of diversity in science and the protection of human and/or animal subjects. By the completion of the proposed 5-year funding period, we will have selected and trained at least 6 promising new investigators in the field of aging. These early stage investigators will acquire the necessary data, research experience, and mentorship to generate and test new hypotheses regarding FPTs and compete successfully for independent funding for their future research. These individuals will enrich the nation’s workforce with future leaders who will continue to develop new interventions to promote physical function in old age and also train future generations of investigators to continue vital work on this important theme.
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