Population-Specific Eating Disorder Risk Factors in Sexual Minority Women

项目摘要 在所有精神疾病中，饮食失调的死亡率最高，并对健康造成深远的影响。 为那些受影响的人。相对于异性恋同龄人，性少数女性的风险更高， 发展为饮食失调，但对造成这种差异的风险因素知之甚少。的 这个独立之路奖的总体目标是获得所需的高级培训和指导 作为一名独立调查员， 造成性少数群体的不平等。为了实现这一目标，一个多方面的培训计划 包括课程，培训，指导和研究，建议在：（1）社区为基础的和社区- 参与研究，（2）混合方法设计和分析，（3）性少数群体健康公平性研究。的 从本培训计划中获得的知识将为Simone博士执行拟议的研究做好准备，包括 三项研究目标和两项数据收集工作。在K99阶段，采用混合方法病例对照 一项研究将在性少数女性中获得广泛的人群特异性饮食失调风险因素（Aim 1)通过对进食障碍症状、社会文化压力和少数民族的大量定量评估， 压力，以及记录对歧视，社会压力和饮食失调的反应的视频日记 真实的情节。目标1和社区利益相关者咨询委员会（n=6）的结果将告知 后续研究的范围。健康差异研究的一个众所周知的局限性是缺乏经过验证的 用于少数民族样本的措施。根据NIH的优先事项，在R 00阶段， 将在社区咨询的指导下制定饮食失调风险因素的衡量标准（目标2） 目标1中的董事会和相关主题。对30名性少数女性的认知访谈将阐明 每个条目的内容效度。量表的心理测量学特性将来自目标3样本。 最后，人群特异性风险因素与饮食失调行为之间的关联的暂时性 以及这种关系因性别身份而不同的程度（例如，同性恋）、种族和民族（目标3） 采用病例对照研究中的每日过程生态瞬时评估。拟议中的小说 混合方法研究将阐明未充分研究的人群特异性饮食失调风险因素 性少数女性。确定人群特异性风险因素及其与 饮食失调症状在种族和民族多样化的性少数妇女将产生指导方针， 社区计划和干预努力，以纠正差距，拟议的措施将提高 监测特定人群饮食失调风险，并推动未来对此类机制研究。这 该奖项将通过为创新的多方法职业生涯奠定基础来启动PI的独立性 研究可应用于存在差异且存在差异的其他心理健康结果 其他不同的性和性别少数群体。

PROJECT SUMMARY Eating disorders have the highest mortality rate of all psychiatric illnesses and profound health consequences for those affected. Relative to their heterosexual peers, sexual minority women are at heightened risk of developing an eating disorder, yet little is known about the risk factors contributing to this disparity. The overarching goal of this Pathway to Independence Award is to gain advanced training and mentorship required to launch Dr. Simone's career as an independent investigator who rigorously investigates the mechanisms contributing to disparities in sexual minority populations. To achieve this goal, a multifaceted training plan including coursework, training, mentorship, and research is proposed in: (1) community-based and community- engaged research, (2) mixed-methods design and analysis, and (3) sexual minority health equity research. The knowledge derived from this training plan will prepare Dr. Simone to execute the proposed research, including three research aims and two data collection efforts. During the K99 phase, a mixed-methods case-control study will gain a broad scope of population-specific eating disorder risk factors in sexual minority women (Aim 1) through rich quantitative assessments about eating disorder symptoms, sociocultural pressures and minority stress, and video diaries that capture the response to discrimination, social pressure, and eating disorder episodes in real time. The results from Aim 1 and the community stakeholder advisory board (n=6) will inform the scope of the subsequent research. A well-known limitation of health disparity research is a lack of validated measures for use with minority samples. In line with NIH priorities, during the R00 phase, a population-specific measure of eating disorder risk factors will be developed (Aim 2) with guidance from the community advisory board and pertinent themes from Aim 1. Cognitive interviews with 30 sexual minority women will elucidate the content validity of each item. The psychometric properties of the scale will be derived from the Aim 3 sample. Finally, the temporality of associations between population-specific risk factors and eating disorder behaviors and the extent to which such relations differ by sexual identity (e.g., queer, lesbian), race, and ethnicity (Aim 3) by employing a daily process ecological momentary assessment in a case-control study. The proposed novel mixed-methods research will elucidate population-specific eating disorder risk factors in an understudied population, sexual minority women. Identification of population-specific risk factors and their associations with eating disorder symptoms in racially and ethnically diverse sexual minority women will produce guidelines for community programs and intervention efforts to rectify disparities, and the proposed measure will enhance surveillance of population-specific eating disorder risk and advance future research of such mechanisms. This award will launch the PI's independence by laying a foundation for a career in innovative multi-method research that may be applied to additional mental health outcomes wherein disparities are present and with other diverse sexual and gender minority populations.