The Adherence Promotion with Person-centered Technology (APPT) Project: Promoting Adherence to Enhance the Early Detection and Treatment of Cognitive Decline

以人为本的技术 (APPT) 项目的依从性促进：促进依从性以加强认知衰退的早期发现和治疗

• 批准号: 10306973
• 负责人: Walter Richard Boot
• 金额: $ 8.49万
• 依托单位: FLORIDA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10306973
• 关键词: Address; Adherence; Aging; Area; Artificial Intelligence; Behavior; Behavioral; Cellular Phone; Cognitive; Collection; Complex; Computers; Data; Early Diagnosis; Early treatment; Elderly; Ensure; Face; Failure; Goals; Health; Health Policy; Health behavior; Health system; Impaired cognition; Individual; Intervention; Machine Learning; Measures; Mentors; Mentorship; Minority Groups; Postdoctoral Fellow; Process; Professional Meetings and Conferences; Protocols documentation; Public Health; Public Health Schools; Randomized Controlled Trials; Research; Research Design; Research Personnel; Science; Scientist; Supervision; Tablets; Techniques; Technology; Training; Underrepresented Populations; United States National Institutes of Health; Woman; algorithm development; base; career development; design; digital; doctoral student; ethnic minority population; experience; graduate student; improved; meetings; member; parent grant; person centered; phenotypic biomarker; prediction algorithm; prevent; racial minority; research and development; smartphone Application; success; successful intervention; trait; wearable device

Black scientists are underrepresented in health-related research fields and women from racial and ethnic minority groups face particular challenges at the graduate level and beyond. The goal of this supplement, consistent with the priorities of NIH, is to address this gap and promote diversity in behavioral and biomedical health research by providing support for Ibukun E. Fowe, a Public Health PhD student in the department of Health Systems and Policy at the OHSU-PSU School of Public Health and member of an underrepresented group in health-related sciences, to gain experience conducting research in the area of understanding older adults’ adherence to technology-based interventions to measure and support health behaviors, including behaviors that predict or prevent cognitive impairment. This support is aimed to aid Fowe transition from graduate student to post-doctoral researcher and gain background and research experience to help ensure her success as an independent investigator. She will gain experience supervising and participating in the implementation of complex randomized controlled trials, an understanding of the potential of machine learning techniques to detect and prevent cognitive impairment, and additional training through supplemental activities developing and conducting studies that will explore barriers to the collection and use of older adults’ digital phenotypic and biomarker information through wearable devices and smartphone applications. This will serve the parent grant by expanding the impact of each specific aim (SA); SA1) enhancing adherence to cognitive intervention and assessment protocols - digital phenotypic and biomarker information provide useful state and trait information about individuals which can enhance predictions of adherence failures, SA2) improving understanding of barriers to long-term adherence –the study of barriers to long- term adherence will be extended to technologies beyond tablet and smartphone assessments and interventions through supplemental activities involving wearables, and SA3) assisting in the development of algorithms for predicting and preventing adherence failures –Fowe, working with the data and computer scientists of the APPT team, will investigate how digital phenotypic and biomarker information might provide additional context to enhance predictions of adherence lapses and improve the timing of reminders to maximize successful intervention reengagement. We have developed a tailored plan for Ibukun Fowe’s research and career development. This plan includes 1) supervised mentoring and mentorship sessions; 2) active involvement in the research design and analysis process; 3) active involvement in the dissemination of study findings; 4) interactions with other researchers and scientists, and 5) networking through the process of participation in scientific activities such as professional meetings, conferences, and research meetings.

黑人科学家在与卫生相关的研究领域和种族和族裔的妇女中的人数不足 少数群体在研究生层面及以后面临特定的挑战。这种补充的目标， 与NIH的优先事项一致，是解决这一差距并促进行为和生物医学的多样性 卫生研究通过为Ibukun E. Fowe提供支持， OHSU-PSU公共卫生学院的卫生系统和政策和人数不足的成员 与健康相关的科学团体，获得在了解较老的领域进行研究的经验 成人遵守基于技术的干预措施，以衡量和支持健康行为，包括 预测或防止认知障碍的行为。此支持旨在帮助Fowe从 博士后研究人员的研究生并获得背景和研究经验，以帮助她 作为独立研究者的成功。她将获得监督和参加的经验 实施复杂的随机对照试验，了解机器学习的潜力 检测和防止认知障碍的技术，以及通过补充活动进行的额外培训 开发和进行研究，将探索收集和使用老年人数字的障碍 通过可穿戴设备和智能手机应用程序的表型和生物标志物信息。这将服务 父母赠款通过扩大每个特定目标（SA）的影响； SA1）增强对认知的依从性 干预和评估协议 - 数字表型和生物标志物信息提供了有用的状态和 有关个人的特质信息，可以增强依从性失败的预测，SA2）改善 了解长期遵守障碍 - 对长期遵守障碍的研究将是 扩展到平板电脑和智能手机评估和干预措施以外的技术。 涉及可穿戴设备的活动，SA3）协助开发用于预测和的算法 防止依从性失败 - 与APPT团队的数据和计算机科学家一起工作，将 调查数字表型和生物标志物信息如何提供其他上下文以增强 预测依从性失误并改善提醒的时间，以最大程度地提高干预措施 重新参与。我们已经为Ibukun Fowe的研究和职业发展制定了量身定制的计划。这 计划包括1）监督心理和心态课程； 2）积极参与研究设计 和分析过程； 3）积极参与研究结果的传播； 4）与其他 研究人员和科学家，以及5）参与科学活动的过程，例如 专业会议，会议和研究会议。