The Adherence Promotion with Person-centered Technology (APPT) Project: Promoting Adherence to Enhance the Early Detection and Treatment of Cognitive Decline

以人为本的技术 (APPT) 项目的依从性促进：促进依从性以加强认知衰退的早期发现和治疗

• 批准号: 10306973
• 负责人: Walter Richard Boot
• 金额: $ 8.49万
• 依托单位: FLORIDA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10306973
• 关键词: Address; Adherence; Aging; Area; Artificial Intelligence; Behavior; Behavioral; Cellular Phone; Cognitive; Collection; Complex; Computers; Data; Early Diagnosis; Early treatment; Elderly; Ensure; Face; Failure; Goals; Health; Health Policy; Health behavior; Health system; Impaired cognition; Individual; Intervention; Machine Learning; Measures; Mentors; Mentorship; Minority Groups; Postdoctoral Fellow; Process; Professional Meetings and Conferences; Protocols documentation; Public Health; Public Health Schools; Randomized Controlled Trials; Research; Research Design; Research Personnel; Science; Scientist; Supervision; Tablets; Techniques; Technology; Training; Underrepresented Populations; United States National Institutes of Health; Woman; algorithm development; base; career development; design; digital; doctoral student; ethnic minority population; experience; graduate student; improved; meetings; member; parent grant; person centered; phenotypic biomarker; prediction algorithm; prevent; racial minority; research and development; smartphone Application; success; successful intervention; trait; wearable device

Black scientists are underrepresented in health-related research fields and women from racial and ethnic minority groups face particular challenges at the graduate level and beyond. The goal of this supplement, consistent with the priorities of NIH, is to address this gap and promote diversity in behavioral and biomedical health research by providing support for Ibukun E. Fowe, a Public Health PhD student in the department of Health Systems and Policy at the OHSU-PSU School of Public Health and member of an underrepresented group in health-related sciences, to gain experience conducting research in the area of understanding older adults’ adherence to technology-based interventions to measure and support health behaviors, including behaviors that predict or prevent cognitive impairment. This support is aimed to aid Fowe transition from graduate student to post-doctoral researcher and gain background and research experience to help ensure her success as an independent investigator. She will gain experience supervising and participating in the implementation of complex randomized controlled trials, an understanding of the potential of machine learning techniques to detect and prevent cognitive impairment, and additional training through supplemental activities developing and conducting studies that will explore barriers to the collection and use of older adults’ digital phenotypic and biomarker information through wearable devices and smartphone applications. This will serve the parent grant by expanding the impact of each specific aim (SA); SA1) enhancing adherence to cognitive intervention and assessment protocols - digital phenotypic and biomarker information provide useful state and trait information about individuals which can enhance predictions of adherence failures, SA2) improving understanding of barriers to long-term adherence –the study of barriers to long- term adherence will be extended to technologies beyond tablet and smartphone assessments and interventions through supplemental activities involving wearables, and SA3) assisting in the development of algorithms for predicting and preventing adherence failures –Fowe, working with the data and computer scientists of the APPT team, will investigate how digital phenotypic and biomarker information might provide additional context to enhance predictions of adherence lapses and improve the timing of reminders to maximize successful intervention reengagement. We have developed a tailored plan for Ibukun Fowe’s research and career development. This plan includes 1) supervised mentoring and mentorship sessions; 2) active involvement in the research design and analysis process; 3) active involvement in the dissemination of study findings; 4) interactions with other researchers and scientists, and 5) networking through the process of participation in scientific activities such as professional meetings, conferences, and research meetings.

黑人科学家在健康相关研究领域的代表性不足， 少数群体在研究生和更高层次面临特殊挑战。这个补充的目的， 与NIH的优先事项一致，是解决这一差距，促进行为和生物医学领域的多样性， 健康研究，为Ibukun E. Fowe是公共卫生系的博士生， 卫生系统和公共卫生的OHSU-PSU学校的政策和代表性不足的成员 健康相关科学小组，以获得在了解老年人 成年人坚持以技术为基础的干预措施，以衡量和支持健康行为，包括 预测或预防认知障碍的行为。这一支持旨在帮助Fowe从 研究生到博士后研究员，并获得背景和研究经验，以帮助确保她 作为一名独立的调查员。她将获得监督和参与 实施复杂的随机对照试验，了解机器学习的潜力 检测和预防认知障碍的技术，以及通过补充活动进行的额外培训 开发和开展研究，探讨收集和使用老年人数字信息的障碍; 通过可穿戴设备和智能手机应用程序获取表型和生物标志物信息。这将服务于 通过扩大每个具体目标的影响（SA）的父母补助金; SA 1）增强对认知的坚持 干预和评估协议-数字表型和生物标记信息提供有用状态和 关于个体的特质信息，其可以增强对依从性失败的预测，SA 2）改善 了解长期坚持的障碍-长期坚持的障碍的研究将是 扩展到平板电脑和智能手机以外的技术评估和干预， 涉及可穿戴设备的活动，以及SA 3）协助开发用于预测和 防止遵守失败-Fowe与APPT团队的数据和计算机科学家合作，将 研究数字表型和生物标志物信息如何提供额外的背景， 预测依从性失效，并改进提醒的时间，以最大限度地成功干预 重新订婚我们为Ibukun Fowe的研究和职业发展制定了量身定制的计划。这 该计划包括1）监督指导和导师会议; 2）积极参与研究设计 3）积极参与研究结果的传播; 4）与其他组织的互动 研究人员和科学家，以及5）通过参与科学活动， 专业会议、研讨会和研究会议。