权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Gulf Regional Area Stroke Program and Oklahoma

海湾地区中风计划和俄克拉荷马州

基本信息

批准号：
10306040
负责人：
Sean I Savitz
金额：
$ 30.65万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10306040
关键词：
Adult Alabama Anticoagulants Area Arteries Attention Brain hemorrhage Caring Cerebral hemisphere hemorrhage Clinical Research Clinical Trials Coagulation Process Collaborations Communities Conduct Clinical Trials Development Devices Education Enrollment Environment Lead Leadership Link Louisiana Minority Minority Recruitment Mississippi National Institute of Neurological Disorders and Stroke Oklahoma Oral Patients Phase Philosophy Randomized Clinical Trials Recording of previous events Recovery Rehabilitation therapy Reperfusion Therapy Research Retrieval Scientist Site Stroke Stroke prevention Testing Texas Therapeutic Training United States Universities Woman acute stroke austin bench to bedside career clinical research site design disability ethnic diversity improved metropolitan multidisciplinary novel novel marker patient population pediatric patients post stroke pre-clinical prevent programs randomized trial stroke recovery stroke therapy stroke trials working group

项目摘要

Our center for 30 years has been a leader in clinical trials testing new treatments for stroke and brain hemorrhage. In this application, we aim to continue serving as a leading regional coordinating center (RCC) in StrokeNet and have assembled a well-organized group of connected clinical sites linked by a history of productive collaboration and led by a multidisciplinary and ethnically diverse team. In Specific Aim 1, we intend to continue leading a RCC consisting of multidisciplinary teams to conduct clinical trials testing novel stroke therapies in acute stroke, stroke prevention, and stroke recovery. The UTHealth RCC will conduct clinical trials within a network of inter-connected sites throughout Texas, Oklahoma, and Louisiana, involving both adult and pediatric patients with attention to the recruitment of minorities and women. In specific Aim 2, we will continue to provide expertise and leadership for the design of novel trials and propose trials testing new stroke therapies in acute stroke, stroke prevention, and stroke recovery. We will also provide translational expertise for the development of new stroke therapies from bench to bedside and for the development and testing of novel biomarkers. In specific Aim 3, we will continue to provide a career enhancement program within our network for clinician-scientists with high potential for independent research careers in stroke.

30年来，我们的中心在测试中风和大脑的新疗法的临床试验中一直处于领先地位。大出血。在这项申请中，我们的目标是继续作为领先的区域协调中心 (RCC)在StrokeNet，并组织了一组组织良好的相互连接的临床站点，通过富有成效的合作历史，由一个多学科和种族多元化的团队领导。在……里面具体目标一，我们打算继续领导一个由多学科团队组成的RCC进行在急性卒中、卒中预防和卒中恢复中测试新的卒中疗法的临床试验。 UTHealth RCC将在整个相互连接的站点网络中进行临床试验德克萨斯州、俄克拉何马州和路易斯安那州，涉及成人和儿童患者，并注意招募少数民族和妇女。在具体目标2中，我们将继续提供专业知识和领导设计新的试验，并提出试验测试新的中风疗法中风、中风预防和中风康复。我们还将提供翻译方面的专业知识开发从病床到床边的新中风疗法，并开发和测试新的生物标志物。在具体目标3中，我们将继续提供职业提升计划在我们的临床医生-科学家网络中，他们有很高的独立研究职业潜力卒中。