Advances in Musculoskeletal & Neuronal Interactions

肌肉骨骼的进展

基本信息

  • 批准号:
    10318837
  • 负责人:
  • 金额:
    $ 5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-02-01 至 2023-01-31
  • 项目状态:
    已结题

项目摘要

The public health burden of age-related diseases is increasing rapidly as the number of older adults continues to rise. Osteoporotic fractures are now responsible for more hospitalizations in the United States than heart attack, stroke, and breast cancer combined. Muscle weakness and postural instability are major contributors to the incidence of falls among the elderly, and falling is the primary etiological factor in 90% of hip fractures. Loss of muscle and bone mass with age is therefore a major limiting factor on health span, as the morbidity that accompanies fractures in the elderly is costly both in terms of financial burden and quality of life. A major gap in the advancement of new prevention and treatment strategies for age-related musculoskeletal diseases is a lack of integration from various areas of musculoskeletal research. Our goal is to bring together leaders from these various disciplines to facilitate communication, identify future research directions, and attract young scientists to this emerging, interdisciplinary area of research. The proposed 2021 meeting “Advances in Musculoskeletal & Neuronal Interactions” in Atlanta will include i) a focus on stem biology in muscle and bone, and the role(s) of these cell populations in musculoskeletal crosstalk, ii) new advances in neuromuscular junction structure, function and degradation in aging, iii) tissue engineering approaches for musculoskeletal repair and regeneration, and iv) novel approaches for cellular imaging of muscle and bone tissue. Aim 1 is to bring together research leaders to stimulate new collaborative studies in the area of musculoskeletal and neuronal interactions with an emphasis on age-related impairment. Aim 2 is to inspire new ideas through brainstorming sessions, group discussions, panel discussions, and one-on-one interactions. Aim 3 is to identify means to promote, inform, and support the emerging field of musculoskeletal & neuronal interactions. Aim 4 is to disseminate information regarding such interactions and age-relatedness including latest ideas, state-of-the-art technologies, potential for collaboration, and new opportunities for funding and support. We believe this program reflects the most exciting advances relevant to the fields of aging biology, muscle, bone and neuronal interactions and will serve as the platform to identify promising opportunities and future research directions.
随着老年人数量的不断增加,与年龄有关的疾病的公共卫生负担正在迅速增加

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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HICHAM M DRISSI其他文献

HICHAM M DRISSI的其他文献

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{{ truncateString('HICHAM M DRISSI', 18)}}的其他基金

Role of IL-17 receptor A in aging bone remodeling
IL-17受体A在衰老骨重塑中的作用
  • 批准号:
    10719356
  • 财政年份:
    2023
  • 资助金额:
    $ 5万
  • 项目类别:
Bone anabolic effects of osteoclast-produced phospho-Wnt5a
破骨细胞产生的磷酸化 Wnt5a 的骨合成代谢作用
  • 批准号:
    10929243
  • 财政年份:
    2023
  • 资助金额:
    $ 5万
  • 项目类别:
Control of intervertebral disc degeneration via matrix-mediated delivery of platelet-derived growth factors
通过基质介导的血小板衍生生长因子的传递来控制椎间盘退变
  • 批准号:
    10377961
  • 财政年份:
    2021
  • 资助金额:
    $ 5万
  • 项目类别:
Control of intervertebral disc degeneration via matrix-mediated delivery of platelet-derived growth factors
通过基质介导的血小板衍生生长因子的传递来控制椎间盘退变
  • 批准号:
    10614929
  • 财政年份:
    2021
  • 资助金额:
    $ 5万
  • 项目类别:
CMA: Cartilage Repair Strategies to Alleviate Arthritic Pain (CaRe AP): Novel cell-based therapies to increase functional outcomes and alleviate pain in preclinical models of osteoarthritis
CMA:减轻关节炎疼痛的软骨修复策略 (CaRe AP):基于新型细胞的疗法,可提高骨关节炎临床前模型的功能结果并减轻疼痛
  • 批准号:
    10514601
  • 财政年份:
    2020
  • 资助金额:
    $ 5万
  • 项目类别:
CMA: Cartilage Repair Strategies to Alleviate Arthritic Pain (CaRe AP): Novel cell-based therapies to increase functional outcomes and alleviate pain in preclinical models of osteoarthritis
CMA:减轻关节炎疼痛的软骨修复策略 (CaRe AP):基于新型细胞的疗法,可提高骨关节炎临床前模型的功能结果并减轻疼痛
  • 批准号:
    10292959
  • 财政年份:
    2020
  • 资助金额:
    $ 5万
  • 项目类别:
Spatial and Temporal Role of the Runx3 Transcription Factor in Secondary Fracture Healing
Runx3 转录因子在二次骨折愈合中的时空作用
  • 批准号:
    10454763
  • 财政年份:
    2020
  • 资助金额:
    $ 5万
  • 项目类别:
Spatial and Temporal Role of the Runx3 Transcription Factor in Secondary Fracture Healing
Runx3 转录因子在二次骨折愈合中的时空作用
  • 批准号:
    10618866
  • 财政年份:
    2020
  • 资助金额:
    $ 5万
  • 项目类别:
CMA: Cartilage Repair Strategies to Alleviate Arthritic Pain (CaRe AP): Novel cell-based therapies to increase functional outcomes and alleviate pain in preclinical models of osteoarthritis
CMA:减轻关节炎疼痛的软骨修复策略 (CaRe AP):基于新型细胞的疗法,可提高骨关节炎临床前模型的功能结果并减轻疼痛
  • 批准号:
    10013786
  • 财政年份:
    2020
  • 资助金额:
    $ 5万
  • 项目类别:
Spatial and Temporal Role of the Runx3 Transcription Factor in Secondary Fracture Healing
Runx3 转录因子在二次骨折愈合中的时空作用
  • 批准号:
    9890844
  • 财政年份:
    2020
  • 资助金额:
    $ 5万
  • 项目类别:

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