Vanderbilt-Nigeria Building Research Capacity in HIV and Non-communicable Diseases (NCDs) (V-BRCH)

摘要 范德比尔特-尼日利亚艾滋病毒/非传染性疾病研究能力建设项目（"V-BRCH"） 该计划是一个协调的方法，以建立尼日利亚调查人员的能力，成功地启动和 在艾滋病毒相关非传染性疾病方面开展高质量的临床试验。V-BRCH建立在长期和高度 尼日利亚和美国两个领先的研究机构--阿米努大学之间的成功合作 卡诺教学医院（AKTH）和范德比尔特大学医学中心。V-BRCH将固化大气层 在进行艾滋病毒临床试验方面，为AKTH的医生教师提供持续的指导和技能获取- 通过短期和中期的学习机会，配对辅导安排， 指导研究项目（目标1）。我们将每年选择三名AKTH教师参加高度 有效的年度1个月长的范德比尔特研究发展和道德研究所（"VIRDE"）教师 纳什维尔的浓缩项目我们每年将在尼日利亚举办两次为期两周的现场研讨会， 医生和研究人员在艾滋病毒相关的非传染性疾病流行病学，临床试验方法，和赠款 写作我们将在AKTH确定以研究为导向的初级教职员工（n = 8），在以下关键领域进行重点培训： 需要和临床试验管理和监管监督。学者们将分享最佳实践， 通过指导小组、定期"进行中的工作"会议和每月职业生涯 发展研讨会。将向导师-学员团队（n = 10）提供有竞争力的种子资助，以促进 有针对性的国内试点研究侧重于与艾滋病毒有关的非传染性疾病。至于长期培训（目标2），我们会 支持加强在尼日利亚Bayero大学/AKTH的公共卫生硕士培训（共计：8 在范德比尔特为2名尼日利亚医生提供临床研究理学硕士（MSCI）学位 科学家我们将通过短期培训，建立艾滋病毒相关非传染性疾病临床试验研究的机构能力。 区域课程、工作人员发展讲习班和公共卫生硕士课程改进（目标3）。以利用 补充课程，同侪小组学习和研究网络的机会，V-BRCH将 利用国际金融公司在尼日利亚和撒哈拉以南非洲地区资助的其他培训项目开展的培训活动 （南南合作机会）。V-BRCH代表了多年合作的高潮， 范德比尔特和AKTH之间的研究和培训，并将奠定可持续发展的基础， 在尼日利亚，临床试验研究主要集中在艾滋病毒相关的非传染性疾病上。

ABSTRACT The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (NCDs) (`V-BRCH') program is a coordinated approach to build the capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated NCDs. V-BRCH builds upon long-standing and highly successful collaborations between two leading research institutions in Nigeria and the United States - Aminu Kano Teaching Hospital (AKTH) and Vanderbilt University Medical Center. V-BRCH will solidify an atmosphere of continuous mentoring and skills acquisition for AKTH physician faculty in conducting clinical trials in HIV- associated NCDs via short- and medium- term learning opportunities, paired mentoring arrangements and mentored research projects (Aim 1). We will select three AKTH faculty members per year to attend the highly effective annual 1-month long Vanderbilt Institute for Research Development and Ethics (“VIRDE”) faculty enrichment program in Nashville. We will offer two 2-week, on-site workshops in Nigeria every year for physicians and research staff on HIV-associated NCD epidemiology, clinical trials methodology, and grant writing. We will identify research-oriented junior faculty staff (n=8) at AKTH for focused training in key areas of need and in clinical trials administration and regulatory oversight. Scholars will share best practices and lessons learned through mentoring panels, regular `Works in Progress' meetings, and monthly career development seminars. Competitive seed grants will be provided to mentor-mentee teams (n=10) to promote targeted in-country pilot studies focused on HIV-associated NCDs. For long-term training (Aim 2), we will support enhanced Master of Public Health (MPH) training at Bayero University/AKTH in Nigeria (total: 8 physicians) and Master of Science in Clinical Investigation (MSCI) at Vanderbilt for 2 Nigerian physician scientists. We will build institutional capacity in HIV-associated NCD clinical trials research via short-term regional courses, staff development workshops and MPH curriculum refinement (Aim 3). To take advantage of complementary courses, peer-to-peer group learning and research networking opportunities, V-BRCH will leverage training activities conducted by other FIC-funded training programs in Nigeria and sub-Saharan Africa (South-South collaborative opportunities). V-BRCH represents the culmination of years of collaboration in research and training between Vanderbilt and AKTH and will lay the foundation for sustainable development of clinical trials research focused on HIV-associated NCDs in Nigeria.