Training in Molecular Virology, Viral Pathogenesis and Viral Vectors

分子病毒学、病毒发病机制和病毒载体培训

• 批准号: 10329919
• 负责人: Stanley Perlman
• 金额: $ 12.61万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10329919
• 关键词: Molecular Virology; Training; Viral Pathogenesis; Viral Vector

Project Summary The central objective of this Molecular Virology, Viral Pathogenesis and Viral Vectors Training Grant is to train students in virology so that they can become productive members of the research community. The importance of virology has been highlighted by reports of the morbidity and mortality caused by viruses long known to infect humans as well as the emergence of zoonotic virus infections. Thus, there is an urgent need to continue producing young scientists who are expert in virology. This training grant, which has trained students for 20 years, consists of trainers with interests in a variety of viruses and who are both junior and senior. Our focus is on understanding fundamental aspects of human virology, with an emphasis on emerging virus infections and viral pathogenesis and the development and use of viral vectors for gene delivery. Students who were appointed to the training grant in the past have uniformly completed their Ph.D.s and stayed in the life sciences. There are 18 trainers from several departments and interdisciplinary programs who serve as faculty on this training grant. Their research interests range from the study of very basic processes in the molecular and cellular biology of virus replication, to study of host immune responses to virus infection, to study of the most efficient mechanisms for gene delivery by viruses. The training grant program is rigorous and consists of a mixture of didactic courses, seminars, seminar courses which emphasize critical reading of the literature and data presentation, and teaching opportunities. Trainees are provided feedback in several venues, to hone their presentation and laboratory skills. Its interdisciplinary nature promotes interaction among students and faculty interested in virology across the University of Iowa. By providing stipend support and travel funds for graduate students, the training grant also facilitates exposure of our students to the national and international virology community. Students selected for support by the training grant will have extra opportunities to teach classes and to receive funding to attend an off-campus course in a cutting-edge technology, such as bio- informatics. They will attend seminars at the University in which career options are discussed and will have the opportunity to interact with visiting virologists. Issues of scientific integrity and data reproducibility are also emphasized as part of the virology training grant. We also use the training grant as a mechanism for enhancing racial, ethnic and socio-economic diversity as part of our selection process for trainees. In short, this training grant has had many years of success and we will build upon this success. We continue to request funds for three predoctoral graduate students per year, with support generally provided for two years between their second and fourth years of study.

项目摘要 这项分子病毒学、病毒致病和病毒载体培训基金的中心目标是培训 让学生学习病毒学，这样他们就可以成为研究社区中富有成效的成员。它的重要性 病毒学的最新进展是关于感染病毒引起的发病率和死亡率的报道。 人类以及人畜共患病毒感染的出现。因此，迫切需要继续 培养出精通病毒学的年轻科学家。这笔培训助学金，已经培训了20名学生 多年来，由对各种病毒感兴趣的初级和高级培训人员组成。我们的重点是 了解人类病毒学的基本方面，重点是新出现的病毒感染和 病毒的发病机制以及用于基因传递的病毒载体的开发和使用。 过去获得培训补助金的学生统一完成了博士学位并留了下来 在生命科学领域。有来自几个部门和跨学科项目的18名培训员担任 这笔培训补助金的教职员工。他们的研究兴趣从研究非常基本的过程到 病毒复制的分子和细胞生物学，研究宿主对病毒感染的免疫反应，研究 病毒传递基因的最有效机制之一。培训补助金计划非常严格， 由教学课程、研讨会、研讨会课程组成，强调批判性阅读 文献和数据展示，以及教学机会。在几个地点向受训者提供反馈， 磨练他们的演示和实验室技能。它的跨学科性质促进了学生之间的互动 以及爱荷华大学对病毒学感兴趣的教职员工。通过提供津贴支持和旅行基金 对于研究生，培训助学金也促进了我们的学生接触国内和国际 病毒学社区。获培训津贴资助的学生将有额外的教学机会。 并获得资金，参加一个关于尖端技术的校外课程，如生物- 信息学。他们将在大学参加讨论职业选择的研讨会，并将有 与来访的病毒学家互动的机会。科学完整性和数据的可重复性问题也是 强调作为病毒学培训补助金的一部分。我们还利用培训补助金作为一种机制，以加强 种族、族裔和社会经济多样性是我们挑选受训人员过程的一部分。简而言之，这次培训 格兰特已经取得了多年的成功，我们将在此基础上再接再厉。我们继续为三个人申请资金 每年的博士前研究生，一般在二年级和二年级之间提供两年的支持 四年级的学习。