Quality Assessment Support

本合同对国家毒理学规划司（DNTP）产品及其组成部分（包括数据和报告）的各个方面的准确性、一致性和完整性进行评估，以确定研究实施和记录中值得注意、纠正或改进的领域。由于这些研究、数据和报告是多年来进行/生成的，涉及众多DNTP和承包商人员的贡献，因此需要一个未参与生成数据或报告的承包商来评估这些项目过程中数据的连续性和稳定性，并提醒DNTP注意或纠正问题。这些评估的结果将传达给DNTP工作人员和管理层，以便他们可以解决;这一过程有助于DNTP管理DNTP研究，记录，数据和报告的整体质量。在2021财年，该合同进行的审计包括评估霉菌、饮用水污染物、邻苯二甲酸盐、膳食补充剂、全氟烷基和多氟烷基物质（PFAS）、防晒成分、增塑剂和工业化学品的毒理学研究报告和数据。还有几项审计活动支持新病理学同行评审管理软件的验证，以支持所有DNTP毒理学研究。

This contract conducts assessments of the accuracy, consistency and completeness of various aspects of products from the Division of the National Toxicology Program (DNTP) and their components including data and reports in order to identify areas in the conduct and documentation of studies that merit attention, correction or improvement. As these studies, data and reports are conducted/generated over many years and involve contributions of numerous DNTP and contractor personnel, a single contractor that has not been involved in generation of the data or reports is needed to assess the continuity and stability of data over the course of these projects and alert the DNTP on issues that require attention or correction. Findings from these assessments are communicated to DNTP staff and management so they may be addressed; this process aids the DNTP in managing the overall quality of DNTP studies, records, data and reports. During FY21, the audits conducted by this contract included assessment of reports and data from toxicology studies on mold, drinking water contaminants, phthalates, dietary supplements, per- and polyfluoroalkyl substances (PFAS), sunscreen ingredients, plasticizers, and industrial chemicals. There were also several audit activities supporting the validation of a new pathology peer review management software to support all DNTP toxicology studies.