Quality Assessment Support

质量评估支持

• 批准号: 10816966
• 负责人: Steve Brecher
• 金额: $ 52.4万
• 依托单位: CONSOLIDATED SAFETY SERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10816966
• 关键词: Address; Area; Attention; Chemicals; Communication; Computer software; Contractor; Contracts; Data; Documentation; Electronics; Generations; Human Resources; Industrialization; Laboratories; Molds; National Toxicology Program; Pathology; Peer Review; Plasticizers; Poly-fluoroalkyl substances; Process; Records; Reporting; Sunscreening Agents; Toxicology; Validation; Water Pollutants; dietary supplements; drinking water; improved; phthalates

This contract conducts assessments of the accuracy, consistency and completeness of various aspects of products from the Division of Translational Toxicology (DTT), the National Institute of Health Sciences (NIEHS), and the National Toxicology Program (NTP) and their components, including data and reports, in order to identify areas in the conduct and documentation of studies that merit attention, correction or improvement. As these studies, data and reports are conducted/generated over many years and involve contributions of numerous stakeholders, including DTT/NIEHS, NTP, and contractor personnel, a single contractor that has not been involved in generation of the data or reports is needed to assess the continuity and stability of data over the course of these projects and alert the DTT on issues that require attention or correction. Findings from these assessments are communicated to DTT staff and management so they may be addressed; this process aids the DTT in managing the overall quality of DTT/NIEHS and NTP studies, records, data and reports. During FY22, the audits conducted by this contract included assessment of reports and data from toxicology studies on mold, pesticide contents, drinking water contaminants, phthalates, dietary supplements, per- and polyfluoroalkyl substances (PFAS), plasticizers, and industrial chemicals.

本合同对转化毒物学部(DTT)、国家健康科学研究所(NIEHS)和国家毒理学计划(NTP)产品的各个方面及其组成部分(包括数据和报告)的准确性、一致性和完整性进行评估，以确定进行和记录研究中值得关注、纠正或改进的领域。由于这些研究、数据和报告是多年进行/生成的，涉及许多利益相关者的贡献，包括DTT/NIEHS、NTP和承建商人员，因此需要一个没有参与生成数据或报告的单一承包商来评估这些项目过程中数据的连续性和稳定性，并就需要注意或更正的问题向DTT发出警报。这些评估的结果将传达给DTT员工和管理层，以便解决这些问题；这一过程有助于DTT管理DTT/NIEHS和NTP研究、记录、数据和报告的整体质量。在22财年，该合同进行的审计包括对霉菌、农药含量、饮用水污染物、邻苯二甲酸盐、膳食补充剂、全氟烷基物质(PFAS)、增塑剂和工业化学品的毒理学研究的报告和数据进行评估。