Framing HPV Vaccination Messages for African American Parents

项目总结 2014年总统癌症小组称未充分使用HPV疫苗对 抗癌方面的进展。“癌症登月蓝丝带小组，最近发现，扩大 使用HPV疫苗作为癌症预防的首要任务，特别是在医疗服务不足的人群中。 拟议项目的总体目标是开发和评估一种基于理论的新颖信息 框架干预以加速非裔美国青少年接受HPV疫苗。基于 前景理论和健康信念模型，这个项目的目的是1)开发适合文化的信息 框定得失，并通过社区参与预先测试这些信息；2)确定 信息框架(得失)是否/如何影响非裔美国父母接受 HPV疫苗受到他们对HPV和HPV疫苗的先前信念的影响；以及3)评估疗效 一种根植于利用移动平板电脑实现高效的消息定向原则的消息框架干预 通过基于临床的随机试验进行靶向治疗。拟议的项目将产生对 信息框架在推广HPV疫苗接种中的说服作用。它会产生固体 围绕旨在加速的新颖的、基于理论的信息框架干预的经验证据 非裔美国青少年中的HPV疫苗接种情况。解决健康差距的一个关键方面 对非裔美国人社区不利的是，这项研究代表了一项系统和及时的努力 响应2014年总统癌症小组关于优化沟通的紧迫性的呼吁 在主要利益攸关方中推广HPV疫苗接种的战略。

PROJECT SUMMARY The 2014 President’s Cancer Panel called underuse of HPV vaccines “a serious, but correctable threat to progress against cancer.” The Cancer Moonshot Blue Ribbon Panel, more recently, identified expanding the use of HPV vaccines as a top priority for cancer prevention, especially in medically underserved populations. The overarching goal of the proposed project is to develop and evaluate a novel, theory-based message framing intervention to accelerate HPV vaccine uptake among African American adolescents. Based on prospect theory and the health belief model, this project aims to 1) develop culturally appropriate messages framed in gains and losses and pretest these messages through community engagement; 2) determine whether/how the effects of message framing (gain vs. loss) on African American parents’ acceptance of the HPV vaccine are moderated by their prior beliefs about HPV and the HPV vaccine; and 3) evaluate the efficacy of a message framing intervention rooted in message targeting principles utilizing mobile tablets for efficient targeting through a clinic-based randomized trial. The proposed project will generate key insights into the persuasive effects of message framing as applied to the promotion of HPV vaccination. It will produce solid empirical evidence surrounding a novel, theory-based message framing intervention aimed at accelerating HPV vaccine uptake among African American adolescents. Addressing a critical aspect of health disparities disadvantaging the African American community, this research represents a systematic and timely effort to respond to the call of the 2014 President’s Cancer Panel on the urgency of optimizing communication strategies for promoting HPV vaccination among key stakeholders.