Tissue Engineering and Regenerative Medicine Undergraduate Research Addressing Challenges in Kidney and Urologic Diseases

组织工程和再生医学本科生研究应对肾脏和泌尿系统疾病的挑战

• 批准号: 10332772
• 负责人: Emmanuel C. Opara
• 金额: $ 10.8万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10332772
• 关键词: Address; Area; Assessment tool; Bioethics; Biological Sciences; Biomedical Engineering; Biomedical Research; Bladder; Communication Programs; Communities; Companions; Coupled; Development; Doctor of Philosophy; Education; Education Projects; Educational workshop; Engineering; Evaluation; Faculty; First Generation College Students; Funding; Goals; Government; Health Sciences; Healthcare; Industry; Institutes; Interdisciplinary Study; Intervention; Kidney; Kidney Diseases; Knowledge; Learning; Measures; Medicine; Mentors; Methods; Minority Groups; Minority-Serving Institution; National Institute of Diabetes and Digestive and Kidney Diseases; Nephrology; Non-traditional Students; Oral; Participant; Perception; Population Heterogeneity; Prevention; Regenerative Medicine; Research; Research Activity; Research Institute; Research Personnel; Research Priority; Schools; Science; Scientist; Self Perception; Site; Students; Tissue Engineering; Training; Underrepresented Minority; Underrepresented Students; United States National Institutes of Health; Universities; Urologic Diseases; Urology; Virginia; Woman; Work; career; career development; cohort; experience; forest; graduate student; health disparity; instrumentation; interest; matriculation; meetings; multidisciplinary; novel; peer; physical science; posters; programs; recruit; responsible research conduct; skill acquisition; student mentoring; student participation; success; summer institute; summer research; symposium; undergraduate research; undergraduate research experience; undergraduate student; virtual

PROJECT SUMMARY This 5-year Summer Undergraduate Research Institute for Meeting Challenges in Kidney and Urologic Diseases (KUD) at the Wake Forest Institute for Regenerative Medicine (WFIRM), offers diverse cohorts of 8 undergraduate students each summer (2022-2027) 10-week multidisciplinary research opportunities utilizing tissue engineering and regenerative medicine (TERM) strategies to address challenges relevant to the prevention, and treatment of kidney and urologic diseases. With interest in addressing the perseverance of the “leaky pipeline” negatively impacting the diversity of the biomedical workforce, we focus on participation of under-represented minority groups, women, and non-traditional students – including students attending 2- and 4- year universities with limited research and first-generation students. Through companion foci of disparities in KUD research and health care, coupled with research courses for skill development and novel educational/career persistence interventions to support student participants, we expect to: 1) enhance diverse students’ participation, learning and mentored research experience with faculty and near-peer graduate mentors during and beyond the 10-week on-site program; 2) enhance students’ knowledge, career intentions and persistence in TERM in KUD research, specifically, and careers in biomedical research broadly; 3) develop and implement a specialized career intentions and perceptions evaluation approach; 4) make a bigger impact on the community; and 5) increase matriculation into graduate, PhD, and MD/PhD programs and careers with focus in TERM and KUD research. These goals will be accomplished via a highly coordinated, mentored interdisciplinary summer research institute with a combination of hands-on and “virtual” research activities, instrumentation training, didactic components, specialized workshops, seminars and mini courses available across participating departments and centers and other funded NIDDK R25 programs, spanning bioethics, responsible conduct of research, health disparities, oral and written communications, and program-tailored education and career development perceptions and intentions evaluation. All students provide an oral overview of their research, present scientific posters at the NIDDK Summer Research Symposium and will be provided institutional support for submitting abstracts for presentation at regional and national conferences. The program incorporates WFIRM faculty, near-peer graduate students and leverages partnerships with the WFSM Department of Urology, the VT- WF School of Biomedical Engineering and Sciences and the WFIRM Bladder Research Center. Achieving our goals will be facilitated by multiple extant regional and national partnerships with scientific, educational and minority serving institutions to enhance recruitment, professional development and, notably, retain focus on KUD research priorities. Overall, we expect these activities and approaches will reinforce positive alignment between self-perceptions, perceptions of scientists, and career intentions and success in TERM and KUD research fields across academic, government, and industry sectors.

项目摘要 这个为期5年的夏季本科研究所，以应对肾脏和泌尿系统疾病的挑战 (KUD)在维克森林再生医学研究所（WFIRM），提供8个不同的队列 本科生每年夏天（2022-2027）10周的多学科研究机会，利用 组织工程和再生医学（$TERM）的战略，以解决有关的挑战 预防和治疗肾脏和泌尿系统疾病。有兴趣解决的毅力， “泄漏管道”对生物医学劳动力的多样性产生负面影响，我们专注于参与 代表性不足的少数群体、妇女和非传统学生-包括参加 2-以及研究有限和第一代学生的四年制大学。通过伴随的焦点 在库德研究和卫生保健的差距，再加上研究课程的技能发展和新的 教育/职业持续干预，以支持学生参与者，我们希望：1）加强多样化 学生的参与，学习和指导的研究经验与教师和近同行的研究生导师 在为期10周的现场课程期间及之后; 2）增强学生的知识，职业意向和 坚持TERM在库德研究，具体而言，和职业生涯在生物医学研究广泛; 3）发展和 实施专门的职业意向和看法评估方法; 4）对 社区;和5）增加入学到研究生，博士和MD/博士课程和职业，重点是 TERM和库德研究。这些目标将通过一个高度协调，指导跨学科 夏季研究所与实践和“虚拟”研究活动相结合，仪器 培训、教学内容、专门讲习班、研讨会和小型课程， 部门和中心以及其他资助的NIDDK R25计划，涵盖生物伦理学，负责任的行为， 研究、健康差距、口头和书面交流以及针对具体项目的教育和职业 发展观念和意图评价。所有的学生提供他们的研究口头概述， 在NIDDK夏季研究研讨会上展示科学海报，并将提供机构支持 提交摘要供在区域和国家会议上介绍。该计划包括WFIRM 教师，近同行的研究生，并利用与WFSM泌尿科，VT- WF生物医学工程与科学学院和WFIRM膀胱研究中心。实现我们 将通过现有的多个区域和国家伙伴关系，与科学、教育和 为少数民族服务的机构，以加强招聘，专业发展，特别是保持重点放在库德 研究优先。总体而言，我们预计这些活动和方法将加强 自我认知、对科学家的认知、在$TERM和库德研究领域的职业意向和成功 在学术界、政府和工业部门。