SToP Cancer SPORE: Developmental Research Program

发展研究计划：摘要 发展研究计划(DRP)对北卡罗来纳大学阻止癌症孢子任务的进展至关重要 对胰腺癌发生发展的基本认识，并开发新的治疗方法 接近了。孢子DRP的首要目标是确定和提供创新的研究支持 为胰腺癌研究的关键领域提供关键洞察力的项目。获资助的计划项目应 提供令人信服的证据，证明有潜力在孢子内发展成完整的项目和/或由 经过同行审查的联邦资源(NIH/NCI、国防部)或基金会资源。每年，在机构的支持下，DRP 打算为最多三个项目提供约100,000美元的资金，第二年的资金取决于 第一年的进步。如果高级领导层确定一个项目 尤其有希望。北卡罗来纳大学阻止癌症孢子开发项目的RFA将提供一次 一年，征求北卡罗来纳大学和包括北卡罗来纳州立大学在内的姐妹机构的建议 (NCSU)和北卡罗来纳中央大学(NCCU，一所历史上的黑人学院/大学)。DRP回顾 委员会(DRPRC)将审查专注于胰腺癌基础研究(如癌症)的申请 细胞信号、细胞生物学和遗传学)；转化研究(生物医学工程[BME]， 癌症成像、癌症免疫学/免疫疗法和治疗方法)；以及 研究，包括癌症预防和控制。

DEVELOPMENTAL RESEARCH PROGRAM: ABSTRACT The Developmental Research Program (DRP) is critical to the UNC SToP Cancer SPORE mission to advance basic understanding of pancreatic cancer development and progression, and to develop new therapeutic approaches. The overarching goal of the SPORE DRP is to identify and provide research support for innovative projects that provide key insight into critical areas of pancreatic cancer research. Funded DRP projects should provide compelling evidence of potential to develop into full projects within the SPORE and/or to be funded by peer-reviewed federal (NIH/NCI, DOD) or foundation resources. Each year with institutional support, the DRP intends to fund up to three projects of approximately $100,000, with a second year of funding dependent on progress in the first year. Budget flexibility will be built in if the senior leadership determines that a project is particularly promising. RFAs for the UNC SToP Cancer SPORE developmental projects will be offered once a year, with proposals solicited from UNC, and our sister institutions which include NC State University (NCSU) and NC Central University (NCCU, a historically black college/university). The DRP Review Committee (DRPRC) will review applications focused on pancreatic cancer basic research (such as cancer cell signaling, cell biology, and genetics); translational research (biomedical engineering [BME], cancer imaging, cancer immunology/immunotherapy, and therapeutic approaches); and population research, including cancer prevention and control.