University of Buffalo Clinical and Translational Science Institute

联系PD/PI：墨菲，蒂莫西·F 布法罗翻译联盟(BTC)，其中包括布法罗大学(UB)健康科学 学校、我区主要医疗机构、四个重点研究机构和五个有影响力的社区 合作伙伴已着手制定全面的战略计划，为临床和医疗服务奠定坚实基础 翻译研究，以回应我们的社区需求。布法罗是纽约人口第二多的城市 纽约州，拥有丰富的文化历史。2018年布法罗市代表性不足的少数族裔比例(50%) 与美国2050年的预测相似，布法罗成为美国30年后面貌的一个缩影。 我们人口中有类似比例的人经历了健康差距。我们CTSA中心的愿景是实现 跨翻译领域的创新研究，以改善我们社区和国家的健康。 我们将开发、测试和分享新的方法，让难以参与的人群参与进来，减少健康 我们社会的不平等，代表着“未来的人口”。在我们的愿景指导下，CTSA已经 自从我们的CTSA于2015年8月首次获得资金以来，我们的环境发生了显著的变化 临床和转化性研究的增长。此外，就在过去的一年里，亚利桑那州立大学医学院已经搬进了 一座壮观的新建筑和我们的临床合作伙伴，该地区最大的医疗系统Kaleida Health， 开设了新的Oishei儿童医院，既位于布法罗尼亚加拉医学院，又与 临床和翻译研究中心完全致力于临床和翻译研究，该中心于 2012年。该地区医疗保健和研究的这种快速和持续的增长轨迹导致了 新的21世纪学术健康中心，集医疗、医学教育、临床和翻译为一体 在布法罗市中心的一个校园进行研究，为提高我们CTSA的影响力奠定了基础 再远一点。在推出我们的CTSA的同时，我们通过主办优先参与国家财团 将创新实验室作为团队科学工具进行测试，与多个中心合作解决翻译 我们与CTSA联盟共同开发的研究障碍和共享工具，包括新型健康 信息学工具。我们的CTSA有五个雄心勃勃但可以实现的目标，包括：1)加快创新 与社区、区域利益攸关方和国家财团参与的团队进行翻译研究； 2)培训一支优秀的、多样化的劳动力队伍，以促进发现成果的翻译；3)加强对特殊技术的纳入 生命周期内的人群和难以参与的人群；4)简化临床研究流程 注重质量和效率，注重多点研究；5)开发、测试和共享生物医学 用于集成来自多个来源的数据以加快翻译速度的信息学工具。在我们的愿景指引下表演 为了改善我们社区和国家的健康，我们将继续扩大我们的势头 翻译研究，培训我们多样化的员工队伍，简化流程，让我们的社区参与进来，并积极 向国家财团捐款。 第243页 项目摘要/摘要 联系PD/PI：墨菲，蒂莫西·F 布法罗大学临床和翻译科学研究所(CTSI)是 水牛城翻译联盟，该联盟包括该地区一流的研究、教育和临床 拥有有影响力的社区合作伙伴的机构。CTSI的愿景是进行创新的临床和 旨在缩小健康差距并改善我们社区和国家健康的转化性研究。我们 让我们的社区成为研究合作伙伴，创建一个共享环境，将发现带给 实验室、诊所和社区，造福个人和公共健康。 第244页

Contact PD/PI: Murphy, Timothy F The Buffalo Translational Consortium (BTC), which includes the University at Buffalo (UB) health sciences schools, the major healthcare institutions in our region, four key research institutes and five influential community partners, have embarked on a comprehensive strategic plan to build a strong foundation for clinical and translational research in response to our community needs. Buffalo is the second most populous city in New York State and has a rich cultural history. The proportion of underrepresented minorities in Buffalo in 2018 (50%) parallels that projected for the US in 2050, making Buffalo a microcosm of what the US will look like in 30 years. A similar proportion of our population experiences health disparities. The vision for our CTSA hub is to perform innovative research across the translational spectrum to improve the health of our community and the nation. We will develop, test and share novel approaches to engage difficult-to-engage populations and reduce health disparities in our community, which represents a “population of the future”. Guided by our vision, the CTSA has catalyzed a transformation of our environment since our CTSA was first funded in August 2015 with remarkable growth in clinical and translational research. Further, in just the past year, the UB medical school has moved into a spectacular new building and our clinical partner, Kaleida Health, the largest healthcare system in the region, opened the new Oishei Children’s Hospital, both on the Buffalo Niagara Medical Campus and connected to the Clinical and Translational Research Center devoted entirely to clinical and translational research that opened in 2012. This rapid and continuing trajectory of growth in healthcare and research in the region has resulted in a new 21st century Academic Health Center with healthcare, medical education and clinical and translational research on one campus in the heart of Buffalo, creating a foundation to enhance the impact of our CTSA even further. While launching our CTSA, we have prioritized participation in the national consortium through hosting and testing Innovation Labs as a team science tool, working with multiple hubs on initiatives to solve translational research barriers and sharing tools that we have developed with the CTSA consortium, including novel health informatics tools. Our CTSA has five ambitious but achievable aims, including: 1) Accelerate innovative translational research with teams that engage communities, regional stakeholders and the national consortium; 2) Train an excellent, diverse workforce to advance translation of discoveries; 3) Enhance inclusion of special populations across the lifespan and difficult-to-engage populations; 4) Streamline clinical research processes focusing on quality and efficiency with emphasis on multisite studies; 5) Develop, test and share biomedical informatics tools to integrate data from multiple sources to speed translation. Guided by our vision to perform research to improve the health of our community and the nation, we will continue our momentum to expand translational research, train our diverse workforce, streamline processes, engage our community, and actively contribute to the national consortium. Page 243 Project Summary/Abstract Contact PD/PI: Murphy, Timothy F The University at Buffalo Clinical and Translational Science Institute (CTSI) is the coordinating center of the Buffalo Translational Consortium, which includes the region's premier research, educational and clinical institutions with influential community partners. The vision of the CTSI is to perform innovative clinical and translational research to reduce health disparities and improve the health of our community and the nation. We engage our community as research partners to create a shared environment to bring discoveries in the laboratory, clinic and community to benefit individual and public health. Page 244