Buffalo Clinical and Translational Research Center
Buffalo Clinical and Translational Research Center
批准号:
10729958
负责人:
Timothy F Murphy
金额:
$23.62万
依托单位国家:
美国
项目类别:
财政年份:
2015
资助国家:
美国
项目状态:
已结题
起止时间:
2015-08-12 至 2024-12-31
关键词:
AccelerationAgeCenter for Translational Science ActivitiesCitiesClinicClinicalClinical ResearchClinical SciencesCommunitiesDataDevelopmentDiverse WorkforceEducationEnvironmentEquityFailureFaith-based organizationFoundationsFundingFutureGenderGrowthHealthHealth SciencesHealthcareHealthcare SystemsHeartIndividualInfluentialsInformation LiteracyInstitutionInterventionInterviewLaboratoriesLongevityMeasurementMedicalMedical EducationModelingNew YorkOutcomePamphletsPediatric HospitalsPopulationPredictive AnalyticsProcessPublic HealthPublic Health InformaticsRecommendationRecording of previous eventsReduce health disparitiesResearchResearch InstituteSchoolsScienceServicesSiteSpecial PopulationSpeedStatistical ModelsStrategic PlanningStructureSurvey MethodologySystemTarget PopulationsTestingTrainingTranslational ResearchTranslationsUncertaintyUnderrepresented MinorityUniversitiesVaccinesVisionbiomedical informaticscommunity engagementdata integrationdigital mediadistrustexperiencehealth care servicehealth disparityhealth literacyhealth organizationimprovedinformatics toolinnovationmarginalized populationmedical schoolsmultiple data sourcesnovelnovel strategiesresponsestatistical learningtooltranslational pipelinevaccine hesitancyvaccine refusal
中文摘要
布法罗翻译联盟(BTC),其中包括布法罗大学(UB)健康科学
学校,我们地区的主要医疗机构,四个重点研究机构和五个有影响力的社区
合作伙伴,已经开始了一项全面的战略计划,为临床和
翻译研究,以回应我们的社会需求。布法罗是纽约州第二大人口城市
约克州有着丰富的文化历史。2018年布法罗代表性不足的少数民族比例(50%)
与美国2050年的预测相似,使布法罗成为美国30年后的缩影。
我国人口中同样比例的人经历着健康差距。我们CTSA中心的愿景是
创新的研究,在整个翻译频谱,以改善我们的社区和国家的健康。
我们将开发、测试和分享新的方法,以吸引难以吸引的人群,并减少健康问题。
我们的社会代表着“未来的人口”。在我们的愿景指导下,CTSA
自我们的CTSA于2015年8月首次获得资助以来,
临床和转化研究的增长。此外,在过去的一年里,UB医学院已经进入
一个壮观的新建筑和我们的临床合作伙伴,Kaleida健康,该地区最大的医疗保健系统,
开设了新的Oishei儿童医院,无论是在布法罗尼亚加拉医学院校园,并连接到
临床和转化研究中心完全致力于临床和转化研究,于2009年开业。
2012.该地区医疗保健和研究的快速持续增长导致了
新的21世纪世纪学术健康中心,医疗保健,医学教育,临床和翻译
在布法罗中心的一个校园进行研究,创建一个基础,以提高我们的CTSA的影响,甚至
进一步.在启动我们的CTSA的同时,我们通过主办
并将创新实验室作为团队科学工具进行测试,与多个中心合作,
我们与CTSA联盟开发的研究障碍和共享工具,包括新的健康
信息学工具。我们的CTSA有五个雄心勃勃但可以实现的目标,包括:1)加速创新
与社区、区域利益攸关方和国家联盟合作的团队进行转化研究;
2)培养一支优秀的、多样化的劳动力队伍,以促进发现的翻译; 3)加强对特殊知识的包容性,
整个生命周期的人群和难以参与的人群; 4)简化临床研究过程
注重质量和效率,重点是多中心研究; 5)开发,测试和共享生物医学
信息学工具,以整合来自多个来源的数据,以加快翻译。以我们的愿景为指导,
研究,以改善我们的社区和国家的健康,我们将继续我们的势头,扩大
转化研究,培训我们多样化的员工队伍,简化流程,参与我们的社区,并积极
为国家财团做贡献。
英文摘要
The Buffalo Translational Consortium (BTC), which includes the University at Buffalo (UB) health sciences
schools, the major healthcare institutions in our region, four key research institutes and five influential community
partners, have embarked on a comprehensive strategic plan to build a strong foundation for clinical and
translational research in response to our community needs. Buffalo is the second most populous city in New
York State and has a rich cultural history. The proportion of underrepresented minorities in Buffalo in 2018 (50%)
parallels that projected for the US in 2050, making Buffalo a microcosm of what the US will look like in 30 years.
A similar proportion of our population experiences health disparities. The vision for our CTSA hub is to perform
innovative research across the translational spectrum to improve the health of our community and the nation.
We will develop, test and share novel approaches to engage difficult-to-engage populations and reduce health
disparities in our community, which represents a “population of the future”. Guided by our vision, the CTSA has
catalyzed a transformation of our environment since our CTSA was first funded in August 2015 with remarkable
growth in clinical and translational research. Further, in just the past year, the UB medical school has moved into
a spectacular new building and our clinical partner, Kaleida Health, the largest healthcare system in the region,
opened the new Oishei Children’s Hospital, both on the Buffalo Niagara Medical Campus and connected to the
Clinical and Translational Research Center devoted entirely to clinical and translational research that opened in
2012. This rapid and continuing trajectory of growth in healthcare and research in the region has resulted in a
new 21st century Academic Health Center with healthcare, medical education and clinical and translational
research on one campus in the heart of Buffalo, creating a foundation to enhance the impact of our CTSA even
further. While launching our CTSA, we have prioritized participation in the national consortium through hosting
and testing Innovation Labs as a team science tool, working with multiple hubs on initiatives to solve translational
research barriers and sharing tools that we have developed with the CTSA consortium, including novel health
informatics tools. Our CTSA has five ambitious but achievable aims, including: 1) Accelerate innovative
translational research with teams that engage communities, regional stakeholders and the national consortium;
2) Train an excellent, diverse workforce to advance translation of discoveries; 3) Enhance inclusion of special
populations across the lifespan and difficult-to-engage populations; 4) Streamline clinical research processes
focusing on quality and efficiency with emphasis on multisite studies; 5) Develop, test and share biomedical
informatics tools to integrate data from multiple sources to speed translation. Guided by our vision to perform
research to improve the health of our community and the nation, we will continue our momentum to expand
translational research, train our diverse workforce, streamline processes, engage our community, and actively
contribute to the national consortium.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
University of Buffalo Clinical and Translational Science Institute - Supplement Schulyer
-
批准号:10516586
-
项目类别:
-
资助金额:$4.76万
-
财政年份:2022
-
负责人:Timothy F Murphy
-
依托单位:
CTSA Administrative Supplement QA/QC
-
批准号:10382581
-
项目类别:
-
资助金额:$9.46万
-
财政年份:2021
-
负责人:Timothy F Murphy
-
依托单位:
Igniting Hope: Mobilizing Community Resources to Achieve Health Equity 2020
-
批准号:10238148
-
项目类别:
-
资助金额:$2.47万
-
财政年份:2020
-
负责人:Timothy F Murphy
-
依托单位:
Igniting Hope: Mobilizing Community Resources to Achieve Health Equity 2020
-
批准号:10453706
-
项目类别:
-
资助金额:$2.46万
-
财政年份:2020
-
负责人:Timothy F Murphy
-
依托单位:
University of Buffalo Clinical and Translational Science Institute
-
批准号:10335251
-
项目类别:
-
资助金额:$392.61万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
University of Buffalo Clinical and Translational Science Institute
-
批准号:10516562
-
项目类别:
-
资助金额:$3.42万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
Buffalo Clinical and Translational Research Center
-
批准号:9125896
-
项目类别:
-
资助金额:$337.31万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
University of Buffalo Clinical and Translational Science Institute
-
批准号:10053435
-
项目类别:
-
资助金额:$411.81万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
University of Buffalo Clinical and Translational Science Institute
-
批准号:10707562
-
项目类别:
-
资助金额:$6.52万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
University of Buffalo Clinical and Translational Science Institute
-
批准号:10544002
-
项目类别:
-
资助金额:$387.63万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
University of Buffalo Clinical and Translational Science Institute
-
批准号:10707561
-
项目类别:
-
资助金额:$6.0万
-
财政年份:2015
-
负责人:Timothy F Murphy
-
依托单位:
Moraxella catarrhalis: virulence-based prevention
-
批准号:8496752
-
项目类别:
-
资助金额:$30.58万
-
财政年份:2012
-
负责人:Timothy F Murphy
-
依托单位:
Moraxella catarrhalis: virulence-based prevention
-
批准号:8865744
-
项目类别:
-
资助金额:$9.31万
-
财政年份:2012
-
负责人:Timothy F Murphy
-
依托单位:
Moraxella catarrhalis: virulence-based prevention
-
批准号:8670720
-
项目类别:
-
资助金额:$32.12万
-
财政年份:2012
-
负责人:Timothy F Murphy
-
依托单位:
Moraxella catarrhalis: virulence-based prevention
-
批准号:9086327
-
项目类别:
-
资助金额:$32.12万
-
财政年份:2012
-
负责人:Timothy F Murphy
-
依托单位:
Moraxella catarrhalis: virulence-based prevention
-
批准号:8857407
-
项目类别:
-
资助金额:$41.04万
-
财政年份:2012
-
负责人:Timothy F Murphy
-
依托单位:
Moraxella catarrhalis: virulence-based prevention
-
批准号:8339258
-
项目类别:
-
资助金额:$32.12万
-
财政年份:2012
-
负责人:Timothy F Murphy
-
依托单位:
Training the Next Generation of Physician Scientists
-
批准号:9304953
-
项目类别:
-
资助金额:$4.34万
-
财政年份:2011
-
负责人:Timothy F Murphy
-
依托单位:
Training the Next Generation of Physician Scientists
-
批准号:9150849
-
项目类别:
-
资助金额:$4.39万
-
财政年份:2011
-
负责人:Timothy F Murphy
-
依托单位:
Training the Next Generation of Clinician Scientist
-
批准号:10655646
-
项目类别:
-
资助金额:$8.32万
-
财政年份:2011
-
负责人:Timothy F Murphy
-
依托单位:
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位:
围绕GLP1-Arginine-AGE/RAGE轴构建探针组学方法探索大柴胡汤异病同治的效应机制
-
批准号:81973577
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2019
-
负责人:辛贵忠
-
依托单位:
AGE/RAGE通路microRNA编码基因多态性与2型糖尿病并发冠心病的关联研究
-
批准号:81602908
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:刘括
-
依托单位: