Predoctoral Training in the Pharmacological Sciences

药理学博士前培训

• 批准号: 10347969
• 负责人: David L. Roman
• 金额: $ 38.82万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10347969
• 关键词: Pharmacology; Science; Training; pre-doctoral

________________________ ____PROJECT SUMMARY / ABSTRACT __ ____ ___ _________________ The Pharmacological Sciences Training Program (PSTP) at the University of Iowa seeks to achieve interdisciplinary and integrated training of a diverse cohort of graduate students in Pharmacological Sciences. The result will be successful PhDs who are well prepared for career and leadership positions in pharmacology in academia, government (e.g. regulatory agencies), pharmaceutical companies, biotechs, research institutes, and science-related fields. In addition to training PhDs well-positioned for career success, our outcomes include publication of first-author and collaborative papers, success in obtaining individual, nationally- competitive fellowships, at or below-average time to degree, and establishing an inclusive and supportive environment conducive to intellectual growth and scientific development. This program is built upon a foundation of an existing Interdisciplinary T32 in Pharmacological Sciences established in 2004, and we build on elements of this program with new programmatic, evaluation, and curricular plans, which bring greater focus on mentorship, team science, rigorous and reproducible research, and career development. The pool of trainees eligible for this program at the University of Iowa is talented and deep. Drawing from 53 mentor laboratories in 13 degree-granting programs across 3 colleges (Medicine, Pharmacy, Liberal Arts & Sciences), we aim for 6 trainees per year to join our program, each appointed for two years (their 2nd and 3rd years of graduate study) for a total of 12 trainee positions. We request funding of only 9 positions, however, because the three participating colleges have pledged support of one matching position each. Our 6 proposed trainees are selected annually from a large pool of strong applicants (5-year average: 19). Trainee selection is a holistic evaluation process that considers fairness and diversity, in addition to strength of the applicant. This PSTP aims to be a highly effective mechanism for interdisciplinary training in the Pharmacological Sciences regardless of departmental affiliation. Even after financial support ends, trainees remain actively engaged in the PSTP through and past graduation. Our core course sequence, Principles of Pharmacology and Pharmacogenetics & Pharmacogenomics, provides trainees a deep understanding of classical and modern pharmacology. Additional courses are required, such as Advanced Problem Solving in Pharmacological Sciences, in which trainees work as a team to design collaborative research plans, while Basic Biostatistics and Experimental Design, and Mastering Reproducible Science focus on rigor and reproducibility, a theme threaded throughout all activities of the PSTP. Science Communication in the Digital Age and PSTP-organized career workshops are offerings that broaden the development of career skills to better prepare our trainees for the job market. These courses lead to cohort-building for our trainees from different programs, as they progress through classes and program activities together including research retreats, summer brown bag discussion luncheons, as well as semi- weekly interactions during Pharmacology Seminar.

_ 爱荷华大学的药理学培训计划(PSTP)寻求实现 对不同类型的药理学研究生进行跨学科和综合培训。 结果将是成功的博士，他们为药理学的职业生涯和领导职位做好了充分的准备 在学术界、政府(如监管机构)、制药公司、生物技术公司、研究机构、 以及与科学相关的领域。除了培养为事业成功做好准备的博士之外，我们的成果还包括 发表第一作者和合作论文，成功获得个人，具有国家竞争力 奖学金，达到或低于平均水平，并建立一个包容和支持的环境 有利于智力成长和科学发展。该计划是建立在一个 现有的药理学跨学科T32成立于2004年，我们以此为基础 使用新的计划、评估和课程计划，更多地关注导师和团队 科学，严谨和可重复的研究，以及职业发展。 有资格参加爱荷华大学这一项目的实习生都很有才华，而且很有深度。绘制自 3所大学13个学位授予项目中的53个导师实验室(医学、药学、文科和 ，我们的目标是每年有6名实习生加入我们的计划，每人受聘两年(他们的第二年和第三年 多年研究生学习)，共12个实习生职位。然而，我们只要求提供9个职位的资金， 因为三所参赛院校承诺各自支持一个匹配的职位。我们的6项建议 学员每年都是从大批优秀申请者中挑选出来的(5年平均为19人)。实习生的选择是一个 全面的评估过程，除了考虑申请人的实力外，还考虑公平性和多样性。 PSTP旨在成为一种高效的药理学跨学科培训机制 不分部门隶属关系的科学。即使在财政支持结束后，受训人员仍很积极 在毕业前后都参与了PSTP。我们的核心课程顺序，药理学原理和 药物遗传学和药物基因组学，为学员提供对古典和现代的深刻理解 药理学。还需要额外的课程，例如药理学的高级问题解决 理科，受训者作为一个团队设计合作研究计划，而基础生物统计学和 实验设计和掌握可再生性科学注重严谨和可再生性，这是一个贯穿始终的主题 在PSTP的所有活动中。数字时代的科学传播与PSTP组织的职业生涯 工作坊是拓宽职业技能发展的课程，让我们的实习生为工作做好准备 市场。这些课程为我们来自不同项目的学员带来了队列建设，随着他们的进步 课程和项目活动包括研究静修，夏季棕袋讨论午餐会， 以及药理学研讨会期间每半周一次的互动。