Adaptation and implementation of a Cherokee-based participatory research project to reduce CVD risk

摘要 美国印第安人(AI)的心血管疾病(CVD)患病率是美国的两倍 与非人工授精的患病率相比。在普通人群中制定和实施的方案，以防止 由于独特的环境和文化障碍，心血管疾病可能不适合或不适用于人工智能人群 不同之处。作为切诺基民族的一员，PI提出了一项职业发展计划和研究，以 促进她发展成为预防心血管疾病和其他负面健康后果的干预措施的领导者 在美国印第安人中。第一个具体目标是调整现有的切诺基计划，以最大限度地扩大覆盖范围 更多的切罗基族公民，并解决切罗基族成年人心血管疾病的初级预防问题。这个 第二个目的是进行一项试点研究，以证明调整后的干预措施的可接受性和可行性。 第三个目标是完成严格的职业发展计划，包括指导计划、培训计划和 相关的课程作业。以社区为基础的参与性研究项目集中在俄克拉何马州的Tahlequah 与切诺基民族合作，并建立在部落和PI之间为期三年的研究关系上。在这上面 这一次，PI已经与这个社区合作评估了一个当前由切诺基人创建的项目，请记住 消除，旨在通过以下计划改善选定的年轻成年公民的健康和福祉 在改善饮食和锻炼的同时，教授切罗基人的文化、语言和历史。新节目《旅程》 将在社区参与的情况下开发，将建立在先前计划的基础上，但 包括扩大招生人数，扩大年龄范围，以及灵活的体力活动计划。的目标是 提议的项目是促进社区合作产生特定文化健康的科学。 通过促进文化学习和文化振兴的力量进行干预。拟议的研究和 职业发展计划将使PI在5年内获得R01资金，并成为 在预防心血管疾病和其他负面健康的创新生活方式干预方面，全国公认的领导者 在人工智能机构中的结果。

ABSTRACT American Indians (AI) have the largest prevalence of cardiovascular disease (CVD) in the nation with double the prevalence compared to non-AIs. Programs developed and implemented in the general population to prevent CVD may not be appropriate or effective for AI populations due to unique environmental barriers and cultural differences. The PI, a member of the Cherokee nation, proposes a career development plan and research to facilitate her development into a leader in interventions to prevent CVD and other negative health outcomes among American Indians. The first specific aim is to adapt an existing Cherokee program to maximize reach to more Cherokee Nation citizens and address primary prevention of CVD in Cherokee Nation (CN) adults. The second aim is to conduct a pilot study to demonstrate acceptability and feasibility of the adapted intervention. The third aim is to complete a rigorous career development plan including mentoring plans, training plans, and pertinent coursework. The community-based participatory research project is centered in Tahlequah, Oklahoma with the Cherokee Nation and built on a three-year research relationship between the tribe and the PI. Over this time, the PI has worked with this community to evaluate a current Cherokee-created program, Remember the Removal, that aims to improve the health and well-being of select young adult citizens through programs that teach Cherokee culture, language and history along with improving diet and exercise. The new program, Journey of Cherokees, to be developed with community participation, will build on the prior program’s foundation but include expanded enrollment capacity, a larger age range, and flexible physical activity programs. The goal of the proposed project is to advance the science of community-partnered generation of culturally specific health interventions by promoting the power of cultural learning and cultural revitalization. The proposed research and career development plan will position the PI to obtain R01 funding within the 5-year study period, and to become a nationally recognized leader in innovative lifestyle interventions for preventing CVD and other negative health outcomes among AIs.