Adaptation and implementation of a Cherokee-based participatory research project to reduce CVD risk

摘要 美国印第安人（AI）是全国心血管疾病（CVD）患病率最高的国家， 与非AI相比。在一般人群中制定和实施方案， 由于独特的环境障碍和文化差异，CVD可能不适合AI人群或对其有效。 差异PI是切罗基民族的成员，提出了职业发展计划和研究， 促进她发展成为预防心血管疾病和其他负面健康结果的干预措施的领导者 在美洲印第安人中。第一个具体目标是调整现有的切罗基计划，以最大限度地达到 更多的切罗基民族公民和解决心血管疾病的初级预防切罗基民族（CN）的成年人。的 第二个目标是进行一项试点研究，以证明经调整的干预措施的可接受性和可行性。 第三个目标是完成严格的职业发展计划，包括指导计划，培训计划， 相关课程这个以社区为基础的参与性研究项目以俄克拉荷马州的塔勒阔为中心 与切罗基民族，并建立在部落和PI之间为期三年的研究关系。在此 当时，PI已经与这个社区合作，以评估当前Cherokee创建的程序，请记住， 该计划旨在通过以下项目改善选定的年轻成年公民的健康和福祉， 教授切罗基文化、语言和历史沿着改善饮食和锻炼。新项目，旅程 在社区参与的情况下开发的Cheroeconomy将建立在先前计划的基础上， 包括扩大招生能力、扩大年龄范围和灵活的体育活动计划。的目标 拟议的项目是推进社区合作产生文化特定健康的科学， 通过促进文化学习和文化振兴的力量来进行干预。拟议的研究和 职业发展计划将使PI在5年学习期内获得R01资助，并成为 在预防心血管疾病和其他负面健康的创新生活方式干预方面， AI之间的结果。

ABSTRACT American Indians (AI) have the largest prevalence of cardiovascular disease (CVD) in the nation with double the prevalence compared to non-AIs. Programs developed and implemented in the general population to prevent CVD may not be appropriate or effective for AI populations due to unique environmental barriers and cultural differences. The PI, a member of the Cherokee nation, proposes a career development plan and research to facilitate her development into a leader in interventions to prevent CVD and other negative health outcomes among American Indians. The first specific aim is to adapt an existing Cherokee program to maximize reach to more Cherokee Nation citizens and address primary prevention of CVD in Cherokee Nation (CN) adults. The second aim is to conduct a pilot study to demonstrate acceptability and feasibility of the adapted intervention. The third aim is to complete a rigorous career development plan including mentoring plans, training plans, and pertinent coursework. The community-based participatory research project is centered in Tahlequah, Oklahoma with the Cherokee Nation and built on a three-year research relationship between the tribe and the PI. Over this time, the PI has worked with this community to evaluate a current Cherokee-created program, Remember the Removal, that aims to improve the health and well-being of select young adult citizens through programs that teach Cherokee culture, language and history along with improving diet and exercise. The new program, Journey of Cherokees, to be developed with community participation, will build on the prior program’s foundation but include expanded enrollment capacity, a larger age range, and flexible physical activity programs. The goal of the proposed project is to advance the science of community-partnered generation of culturally specific health interventions by promoting the power of cultural learning and cultural revitalization. The proposed research and career development plan will position the PI to obtain R01 funding within the 5-year study period, and to become a nationally recognized leader in innovative lifestyle interventions for preventing CVD and other negative health outcomes among AIs.