权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Coherence-Based Fetal Ultrasonic Imaging

基于相干性的胎儿超声成像

基本信息

批准号：
10366160
负责人：
Gregg E. Trahey
金额：
$ 47.77万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-01 至 2026-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10366160
关键词：
Abdomen Affect Aneuploidy Anxiety Blinded Cardiac Cesarean section Clinical Research Congenital diaphragmatic hernia Counseling Data Detection Developed Countries Diagnosis Diagnostic Diffuse Discipline of obstetrics Environment Failure Fetal Monitoring Fetal Structures Fetal Viability Fetal health Fetus First Pregnancy Trimester Frequencies Gestational Age Growth and Development function Human Image Image Analysis Imaging Techniques Lead Life Location Maps Maternal Health Measures Methods Morbidity - disease rate Mothers Multiple Pregnancy Noise Obesity Operative Surgical Procedures Ovary Overweight Pathology Patient imaging Patients Pelvis Placenta Pregnancy Property Publishing Research Resolution Role Scanning Second Pregnancy Trimester Source Structure Sum Techniques Translations Ultrasonics Ultrasonography United States Uterus Visualization Woman base comparative cost fetal follow-up imaging modality improved in vivo maternal outcome mortality neonate novel postnatal public health relevance quantitative imaging simulation tertiary care theories ultrasound unnecessary treatment

项目摘要

Abstract Ultrasonic imaging is widely used to monitor fetal growth and development during the first and second trimester, and multiple studies document the resultant positive impacts on fetal and maternal outcomes. However, current methods fail to provide adequate visualization of key structures in many patients, and alternative imaging modes are rarely available to these patients. We have developed novel ultrasonic beamforming methods that utilize the spatial coherence of backscattered echoes. These methods, in simulation, phantom, and blinded-observer clinical studies, show markedly improved image quality over conventional ultrasonic images, especially in difficult-to-image patients. We propose extend our theory of coherence imaging to 1.5D and 2D arrays and to very large arrays. Using such advanced arrays, we propose clinical studies to assess the role of coherence imaging in key fetal diagnostic tasks in first trimester and second trimester scans. Quantitative image quality metrics and observer studies are proposed to compare B-mode and coherence images with an emphasis on difficult-to-image patients for whom current imaging methods fail. Related studies will measure the contribution of various sources of image degradation in fetal scans. If successful, the proposed research could lead to a new class of ultrasonic beamforming methods that operate in imaging environments in which current methods fail.

摘要