Core A: Administrative Core

核心A：行政核心 7.项目概要/摘要 行政核心是COBRE的核心，提供监督、协调和管理 整个中心活动的范围。COBRE的整个经验丰富的领导团队， 负责第一阶段和第二阶段的成功记录，将返回第三阶段。领导班子 包括创始董事和副董事，五名外部咨询委员会成员，他们是 由世界肌肉骨骼研究领域的领导者组成的内部咨询委员会， 我们机构的主要学术和行政领导人，以及包括COBRE在内的指导委员会 核心和项目主管。此外，领导团队也得到了加强， 第一阶段和第二阶段的目标是COBRE调查员。他们将带来自己独特的“成长”经历 在培养环境中培养专业人员，并为指导新一代调查人员作出贡献， 眼镜蛇行政核心的具体目标是：1）在翻译方面提供强有力的领导 通过促进COBRE研究人员在不同学科的科学互动和合作， （生物学家、工程师和临床医生），通过组织包括研究研讨会在内的丰富课程， 多学科期刊俱乐部和赠款讲习班，并促进技术转让和教育; 2） 通过协助收集、处理和分析试点项目的数据，提供生物统计支持， 通过Jason Machan博士指导的统计子单元的研究核心; 3）管理，协调， 监督整个中心的活动，包括优先考虑和分配财政资源， 通过指导委员会实施技术核心和试点项目方案; 4）评估绩效， 成果，并通过编制年度技术核心和试点项目计划进行调整 向外部咨询委员会（EAC）报告，并组织EAC年度会议， 负责试点项目的外部审查、排名和选择，并为一般 5）准备和维护与项目、核心和整体计划相关的文件 管理，实施资源共享计划，并保持沟通，并提交 向NIH提交适当的进度报告; 6）实施COBRE向Brown中心的过渡， 布朗转化科学研究所（BITS）内的肌肉骨骼和运动科学（BCMMS） 对内，对外争取NIH研究翻译中心（CORT）的校外支持。 1

Core A: Administrative Core 7. Project Summary/Abstract The Administrative Core is the nucleus of the COBRE by providing supervision, coordination, and management of the entire range of center activities. The whole experienced leadership team of the COBRE, which has been responsible for the successful track record in Phase I and II, will return for Phase III. The leadership team includes Founding Director and Associate Director, five members of the External Advisory Committee who are leaders in the musculoskeletal research field in the world, the Internal Advisory Committee which consists of key academic and administrative leaders in our Institution, and the Steering Committee which contains COBRE Core and Program Directors. In addition, the leadership team has been enhanced by the addition of graduated target COBRE investigators in Phase I and II. They will bring their unique experience in “growing up” professionally in the nurturing environment and contribute to mentoring of a new generation of investigators in COBRE. The specific aims of the Administrative Core are: 1) Provide strong leadership in translational research by promoting scientific interaction and collaboration of COBRE investigators in different disciplines (biologists, engineers and clinicians), by organizing enrichment programs including research seminars, multidisciplinary journal club, and grant workshops, and by facilitating technology transfer and education; 2) Provide biostatistical support by assisting the collection, handling, and analysis of the data of pilot projects and research cores through the statistical subunit directed by Dr. Jason Machan; 3) Manage, coordinate, and supervise the entire range of center activities including prioritizing and allocating fiscal resources among Technical Cores and Pilot Projects Program through the Steering Committee; 4) Evaluate performance, achievements, and adjustments of Technical Cores and Pilot Projects Program through compiling an annual report to the External Advisory Committee (EAC) and organizing the annual meeting of EAC, which is responsible for external review, ranking, and selection of pilot projects and providing advice for the general direction of COBRE; 5) Prepare and maintain documentation relating to projects, cores and overall program management, implement resource sharing plan, and maintain the communication with and submit the appropriate progress reports to the NIH; 6) Implement the transition of COBRE into Brown Center of Musculoskeletal and Motion Sciences (BCMMS) within the Brown Institute for Translational Sciences (BITS) internally and compete for extramural support of Center of Research Translation (CORT) from NIH externally. 1