MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)
MACS/WIHS 联合队列研究:库克县临床研究中心 (CC_CRS)
基本信息
- 批准号:10371199
- 负责人:
- 金额:$ 299.01万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-04-01 至 2026-03-31
- 项目状态:未结题
- 来源:
- 关键词:AIDS/HIV problemAcquired Immunodeficiency SyndromeAddressAdvisory CommitteesAdvocacyAffectAgeAgingApplications GrantsAreaAwardBehavioral SciencesBiological TestingCardiovascular DiseasesCardiovascular systemCessation of lifeChicagoChronic DiseaseCitiesClinicalClinical DataCohort StudiesCollaborationsCollectionCommunitiesCommunity HealthComplexConsentConsequences of HIVCost efficiencyCountyDataData AnalysesDevelopmentDistressEnrollmentEpidemiologyEthicsFosteringFunctional disorderFundingFutureGoalsGrantHIVHIV therapyHealthHealth SciencesInterventionLanguageLeadLeadershipLearningLifeLiver diseasesLungLung diseasesMalignant NeoplasmsMedicalMental disordersMentorshipMetabolicMorbidity - disease rateNational Institute on Minority Health and Health DisparitiesNeurocognitionNeurocognitiveOral healthOutcomeParticipantPathogenesisPersonsPositioning AttributeProtocols documentationPublicationsQuality of lifeRaceRecording of previous eventsResearchResearch PersonnelResourcesRiskSamplingScienceScientistShipsSiteSleepSpecimenStructureSubstance abuse problemSurveysTimeWomanWomen&aposs Interagency HIV Studyadjudicationantiretroviral therapybehavioral healthcareerclinical research sitecohortcollaborative approachcommunity engagementcomorbiditycookingdisabilityflexibilityimprovedinnovationinsightmenmicrobiomemicrobiome researchmortalitymultidisciplinaryopportunistic pathogenparticipant retentionprematurepreventrecruitsocial mediasocial stigmasocioeconomicsstressorsuccesstranslational approachurban poverty
项目摘要
Project Summary/Abstract
Despite the availability of ever more potent antiretroviral therapy, the struggle to optimize the health of HIV-
infected men and women continues, as they suffer and die from premature medical co-morbidities including
cardiovascular, pulmonary disease, neurocognitive dysfunction and malignancies. The goal of the Chicago Cook
County Clinical Research Site (CRS) of the MACS/WIHS Combined Cohort Study, formerly the Chicago
Women's Interagency HIV Study, is to advance understanding of HIV-related co-morbidities and pathogenesis
through scientific innovation and a translational approach involving investigators from basic, clinical,
behavioral and community health sciences. In collaboration with the other national Clinical Research Sites and
the Data Analysis and Coordinating Center, the site has developed a Unified Science Agenda that aims to
holistically describe mechanisms underlying premature morbidity and mortality in HIV-infected persons. Cook
County CRS investigators will lead or co-lead projects in Behavioral Science, Malignancy, Neurocognition,
Sleep Science and Pathogenesis including initiatives related to Liver Disease, Oral Health, Microbiome Science
and Outcome Adjudication. The Cook County CRS will contribute to HIV and multidisciplinary science by
fostering collaboration through an open, inquisitive approach, sharing ideas and the rich data and specimen
resources of the cohort with qualified experts who can further advance mechanistic understanding of HIV-
associated co-morbidities. The Cook County CRS will also support promising and diverse early career
investigators and those new to HIV research through pilot grants, intentional mentorship, and linkage to
resources to support independent funding. Finally, through expansive engagement of cohort participants and
community partners, the Cook County CRS will rapidly disseminate key study findings and obtain insight into
the most pressing issues for Chicagoans affected by HIV to inform future scientific direction.
项目总结/摘要
尽管有了更有效的抗逆转录病毒疗法,但优化艾滋病毒健康状况的斗争仍在继续,
受感染的男性和女性继续存在,因为他们患有并死于过早的医学合并症,
心血管、肺部疾病、神经认知功能障碍和恶性肿瘤。芝加哥库克的目标
MACS/WIHS联合队列研究的县临床研究中心(CRS),前身为芝加哥
妇女机构间艾滋病毒研究,是为了提高对艾滋病毒相关的合并症和发病机制的认识
通过科学创新和转化方法,涉及基础,临床,
行为和社区健康科学。与其他国家临床研究中心合作,
数据分析和协调中心,该网站已经制定了一个统一的科学议程,旨在
全面描述HIV感染者过早发病和死亡的潜在机制。库克
县CRS调查人员将领导或共同领导行为科学,神经病学,神经认知,
睡眠科学和发病机制,包括与肝脏疾病,口腔健康,微生物组科学相关的举措
结果判定。库克县CRS将通过以下方式为艾滋病毒和多学科科学做出贡献:
通过开放、好奇的方式促进合作,分享想法和丰富的数据和标本,
与合格的专家谁可以进一步推进艾滋病毒的机制理解队列的资源-
相关合并症。库克县CRS还将支持有前途和多样化的早期职业生涯
研究人员和那些新的艾滋病毒研究,通过试点赠款,有意指导,并联系到
支持独立融资。最后,通过广泛参与队列参与者,
社区合作伙伴,库克县CRS将迅速传播关键的研究结果,并获得洞察力,
受艾滋病毒影响的芝加哥人最紧迫的问题,为未来的科学方向提供信息。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Mardge H Cohen其他文献
Commentary: Undocumented women: Pushed from poverty and conflict, pulled into unjust disparity
- DOI:
10.1057/jphp.2009.34 - 发表时间:
2009-12-23 - 期刊:
- 影响因子:1.900
- 作者:
Mardge H Cohen - 通讯作者:
Mardge H Cohen
Mardge H Cohen的其他文献
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{{ truncateString('Mardge H Cohen', 18)}}的其他基金
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS) - OAR Sleep Supplement
MACS/WIHS 联合队列研究:库克县临床研究中心 (CC_CRS) - OAR 睡眠补充剂
- 批准号:
10658775 - 财政年份:2019
- 资助金额:
$ 299.01万 - 项目类别:
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)
MACS/WIHS 联合队列研究:库克县临床研究中心 (CC_CRS)
- 批准号:
10223772 - 财政年份:2019
- 资助金额:
$ 299.01万 - 项目类别:
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)
MACS/WIHS 联合队列研究:库克县临床研究中心 (CC_CRS)
- 批准号:
10612744 - 财政年份:2019
- 资助金额:
$ 299.01万 - 项目类别:
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)
MACS/WIHS 联合队列研究:库克县临床研究中心 (CC_CRS)
- 批准号:
10401710 - 财政年份:2019
- 资助金额:
$ 299.01万 - 项目类别:
MACS/WIHS Combined Cohort Study: Cook County Clinical Research Site (CC_CRS)
MACS/WIHS 联合队列研究:库克县临床研究中心 (CC_CRS)
- 批准号:
9903477 - 财政年份:2019
- 资助金额:
$ 299.01万 - 项目类别:
Improving Adherence Among HIV+ Rwandan Youth: A TI-CBTe Indigenous Leader Model
提高艾滋病毒卢旺达青年的依从性:TI-CBTe 土著领袖模型
- 批准号:
8601541 - 财政年份:2013
- 资助金额:
$ 299.01万 - 项目类别:
Improving Adherence Among HIV+ Rwandan Youth: A TI-CBTe Indigenous Leader Model
提高艾滋病毒卢旺达青年的依从性:TI-CBTe 土著领袖模型
- 批准号:
8432149 - 财政年份:2013
- 资助金额:
$ 299.01万 - 项目类别:
Improving Adherence Among HIV+ Rwandan Youth: A TI-CBTe Indigenous Leader Model
提高艾滋病毒卢旺达青年的依从性:TI-CBTe 土著领袖模型
- 批准号:
8978312 - 财政年份:2013
- 资助金额:
$ 299.01万 - 项目类别:
Women's Interagency HIV Study (WIHS) IV, Chicago Consortium
妇女机构间艾滋病毒研究 (WIHS) IV,芝加哥联盟
- 批准号:
8147902 - 财政年份:2010
- 资助金额:
$ 299.01万 - 项目类别:
Women's Interagency HIV Study (WIHS) IV, Chicago Consortium
妇女机构间艾滋病毒研究 (WIHS) IV,芝加哥联盟
- 批准号:
7919681 - 财政年份:2009
- 资助金额:
$ 299.01万 - 项目类别:
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