Deciphering novel control mechanisms in the skin

破译皮肤的新型控制机制

• 批准号: DP150103714
• 负责人: A/Prof James Wells
• 金额: $ 32.07万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP150103714
• 关键词: Deciphering; novel; control; mechanisms; skin

The overall aim of this project is to understand the cellular mechanisms that maintain skin integrity, and in particular, the role of a novel population of regulatory cells in mediating this process. This is important for our understanding of fundamental physiological interactions in the skin. The proposed research aims to uncover essential new information regarding a recently discovered population of regulatory cells, with particular respect to understanding their mechanisms of action. The outcomes of this work should provide fundamental new knowledge of skin physiology and lead to novel insights regarding how skin integrity may be maintained following the disruption of homeostasis mechanisms.

这个项目的总体目标是了解维持皮肤完整性的细胞机制，特别是一组新的调节细胞在调节这一过程中的作用。这对于我们理解皮肤的基本生理作用是很重要的。这项拟议的研究旨在揭示有关最近发现的一组调控细胞的重要新信息，特别是关于了解它们的作用机制。这项工作的结果应该提供皮肤生理学的基本新知识，并导致关于如何在动态平衡机制被破坏后保持皮肤完整性的新见解。