MUSC Short Term Research Education Program to Increase Diversity

MUSC 短期研究教育计划以增加多样性

• 批准号: 10376143
• 负责人: CYNTHIA F. WRIGHT
• 金额: $ 11.57万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-10 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10376143
• 关键词: Address; Affect; African American population; Area; Award; Bachelor' s Degree; Basic Science; Biochemistry; Biology; Biomedical Research; Cardiac; Cardiovascular Diseases; Cardiovascular Physiology; Cardiovascular system; Career Choice; Clinical; Data; Data Pooling; Development; Diabetes Mellitus; Disabled Persons; Disease; Doctor of Philosophy; Education Projects; Evaluation; Exposure to; Extramural Activities; Faculty; Fatty Acids; Feedback; Fostering; Funding; Goals; Grant; Health Disparities Research; Health Occupations; Hematological Disease; Hypertension; Interview; Journals; Laboratories; Learning; Lung diseases; Lupus; Measures; Medical; Mentors; Methods; Minority Groups; Modeling; Molecular Biology; National Heart, Lung, and Blood Institute; Obesity; Oral; Outcome; Paper; Participant; Peer Review; Professional Education; Proteomics; Publications; Publishing; Regenerative Medicine; Reporting; Request for Applications; Research; Research Activity; Research Ethics; Research Personnel; Research Project Grants; Research Technics; Research Training; Role; Safety; Science; Series; Signal Transduction; Sleep Disorders; Social Functioning; South Carolina; Structure; Students; Surveys; Talents; Training; Training Programs; Translational Research; Underrepresented Populations; Underrepresented Students; United States National Institutes of Health; Universities; Work; biological research; career; clinical implementation; cohort; disadvantaged background; disadvantaged student; doctoral student; education research; epidemiology study; ethnic minority; experience; health care quality; health disparity; improved; interest; lectures; meetings; minority student; next generation; novel strategies; programs; racial and ethnic; racial minority; recruit; responsible research conduct; social; stem cells; symposium; undergraduate research; undergraduate research experience; undergraduate student

PROJECT SUMMARY/ABSTRACT The primary objective of this program is to provide short-term (10 weeks) training experience for fifteen talented students in the area of cardiovascular function and disease. This research education opportunity will be provided to students from disadvantaged backgrounds, racial and ethnic minorities, and others who are underrepresented in biomedical research. The long-range goal is to increase the number of such students in health professions in cardiovascular biology through interest generated by exposure to a broad spectrum of research activities in this area. The 37 Program Faculty participating in the program have been selected on the basis of their active research programs in the areas of cardiovascular disease, cardiovascular development, cardiac stem cells and regenerative medicine, cell signaling, and proteomics that are supported by more than $11.4 million of extramural funds from the NIH/NHLBI. Several of the faculty also conduct clinical and implementation oriented research on diseases that disproportionately affect African Americans, notably hypertension, diabetes, and obesity. Students in the program are intimately involved in the ongoing projects in one of the participating laboratories, and are exposed to many aspects of conducting basic science and epidemiologic research. Students also participate in a lecture series that covers cutting edge topics in biological research, with a focus on topics related to cardiovascular function and disease and clinical/translational research. In addition, the lecture series covers laboratory safety and responsible conduct of research. At the conclusion of the training period, the students prepare a brief written paper and give an oral presentation on their project. They are also encouraged to return in November to present their research at the university-wide annual research day or to attend a national conference such as the Annual Biomedical Research Conference for Minority Students. The program will be evaluated at the end of each year using a combination of qualitative and quantitative approaches including analysis of applicant pool data and recruitment methods, as well as exit interviews and surveys with the students, and feedback from the mentors. Additionally, students' career choices and progress will be tracked by yearly contact with each of the participants.

项目总结/摘要 该计划的主要目标是提供短期（10周）的培训经验， 15名在心血管功能和疾病领域有天赋的学生。这种研究性教育 将为来自弱势背景，种族和少数民族， 以及其他在生物医学研究中代表性不足的人。长期目标是增加 保健专业心血管生物学的此类学生人数， 在这一领域广泛开展研究活动。37名教师参加 在该计划已被选定的基础上，他们积极的研究计划，在这些领域， 心血管疾病，心血管发育，心脏干细胞和再生医学，细胞 信号传导和蛋白质组学，得到了超过1，140万美元的校外资金的支持 NIH/NHLBI。一些教师还进行临床和实施为导向的研究， 这些疾病不成比例地影响非洲裔美国人，特别是高血压、糖尿病和肥胖症。 该计划的学生密切参与正在进行的项目之一， 实验室，并接触到进行基础科学和流行病学的许多方面 research.学生们还参加了一系列讲座，涵盖生物学领域的前沿话题。 研究，重点是与心血管功能和疾病以及临床/翻译相关的主题 research.此外，系列讲座还包括实验室安全和负责任的研究行为。 在培训期结束时，学生准备一个简短的书面报告，并给予口头 介绍他们的项目。他们还被鼓励在11月返回，提出他们的 研究在大学范围内的年度研究日或参加全国会议，如 少数民族学生生物医学研究年会。该方案将在 每年年底采用定性和定量相结合的方法，包括分析 申请人库数据和招聘方法，以及与学生的离职面谈和调查， 以及导师们的反馈此外，学生的职业选择和进展将被跟踪， 每年与每一位参与者接触。

项目成果

The Function of SPARC as a Mediator of Fibrosis.

• DOI: 10.2174/1874312901206010146
• 发表时间: 2012
• 期刊: The open rheumatology journal
• 作者: Trombetta-Esilva J;Bradshaw AD
• 通讯作者: Bradshaw AD

The development of a cognitive rehabilitation task for mice.

针对小鼠的认知康复任务的发展。

• DOI: 10.1016/j.nlm.2020.107296
• 发表时间: 2020-11
• 期刊: Neurobiology of learning and memory
• 影响因子: 2.7
• 作者: Williams A;Lowry T;Sims-Robinson C
• 通讯作者: Sims-Robinson C

LPS induces greater bone and PDL loss in SPARC-null mice.

LPS 会导致 SPARC 缺失小鼠更大的骨量和 PDL 损失。

• DOI: 10.1177/0022034510391800
• 发表时间: 2011
• 期刊: Journal of dental research
• 影响因子: 7.6
• 作者: Trombetta-Esilva,J;Yu,H;Arias,DN;RossaJr,C;Kirkwood,KL;Bradshaw,AD
• 通讯作者: Bradshaw,AD

Lack of nitric oxide synthases increases lipoprotein immune complex deposition in the aorta and elevates plasma sphingolipid levels in lupus.

• DOI: 10.1016/j.cellimm.2012.03.007
• 发表时间: 2012-03
• 期刊: CELLULAR IMMUNOLOGY
• 影响因子: 4.3
• 作者: Al Gadban, Mohammed M.;German, Jashalynn;Truman, Jean-Philip;Soodavar, Farzan;Riemer, Ellen C.;Twal, Waleed O.;Smith, Kent J.;Heller, Demarcus;Hofbauer, Ann F.;Oates, Jim C.;Hammad, Samar M.
• 通讯作者: Hammad, Samar M.

Alk3 mediated Bmp signaling controls the contribution of epicardially derived cells to the tissues of the atrioventricular junction.

• DOI: 10.1016/j.ydbio.2014.09.031
• 发表时间: 2014-12-01
• 期刊: DEVELOPMENTAL BIOLOGY
• 影响因子: 2.7
• 作者: Lockhart, Marie M.;Boukens, Bastiaan J. D.;Phelps, Aimee L.;Brown, Christina-Lin M.;Toomer, Katelynn A.;Burns, Tara A.;Mukherjee, Rupak D.;Norris, Russell A.;Trusk, Thomas C.;van den Hoff, Maurice J. B.;Wessels, Andy
• 通讯作者: Wessels, Andy