AIMDMB Shared Resource Core

计算系统核心（CSC） 正如行政和协调核心研究战略所述， 拟议的AIMINGS中心将实施计算和数据科学方法和工具，以推进 精准健康的营养为了实现这一愿景，数据系统核心（DSC），四个项目， 试点项目，营养精准健康（NPH）联盟，以及更大的精准营养研究 社区可以从一套集成的、随时可用的专用计算资源中受益， 专业知识为每个项目和核心单独提供这种资源可能导致不必要的重复 更重要的是错失了协同效应和机会。每个项目，虽然能够作为一个独立的功能 项目，旨在促进和促进彼此。因此，一组中央计算资源和 专业知识将促进这种融合和共同努力。此外，对于一组 资源和专业知识，不仅要适应项目的发展，还要适应可能需要的发展 为NPH财团和新技术的出现，这将继续发展。此外，这样的 这种情况将使资源和人员更容易从一个项目转移到另一个项目， 培训机会。因此，AIMINGS中心将拥有一个计算系统核心（CSC）， 由计算编程和建模人员组成，将为所有AIMINGS 中心项目以及NPH财团和超越。西点内部计算平台 是CSC中的共享资源，允许跨 目标。我们的CSC团队在计算资源、受控数据的安全性 硬件和应用程序开发，多种编程语言的计算模型开发， 领导许多不同的计算建模和工具开发项目的经验。这些资源 (e.g.,数据存储，处理能力和计算时间）将提供给所有AIMINGS中心核心， 项目，包括试点项目。Aim 1将为用户提供共享的计算和数据资源， AIMINGS中心核心和项目和NPH联盟。目标2将提供数学和 计算建模专业知识和资源，以支持AIMINGS项目和 NPH财团。目标3将提供计算工具开发方面的专业知识和资源， 部署以支持AIMINGS项目和NPH财团的活动。目标 Computational Systems Core将带来多项创新，例如：（1）集成和实现 美国国防部（DoD）的计算能力，以解决营养的精确健康，（2）带来了新的 数据安全水平，营养精准健康，（3）资源和专业知识，以创建新的协作 平台，以及（4）创造新一代的混合，跨学科的研究人员谁有足够的 理解工作的计算和营养/健康方面。

Abstract-Computational Systems Core (CSC) As described in the Administration and Coordination Core (ACC) Research Strategy, the vision of this proposed AIMINGS Center is to implement computational and data science approaches and tools to advance nutrition for precision health. To accomplish this vision the Data Systems Core (DSC), the four projects, the pilot projects, the Nutrition for Precision Health (NPH) Consortium, and the larger precision nutrition research community could benefit from an integrated and readily available set of dedicated computational resources and expertise. Having separate such resources for each project and core could lead to unnecessary redundancy and more importantly missed synergies and opportunities. Each project, while able to function as a stand-alone project, is designed to facilitate and further each other. Thus, a central set of computational resources and expertise would facilitate this integration and work together. Moreover, it will be easier for a single set of resources and expertise to adapt to not only evolution of the projects but also evolution of what may be needed for the NPH consortium and the emergence of new technology, which continues to evolve. Additionally, such a situation will make it easier to shift resources and personnel from one project to another, providing cross- training opportunities. Thus, the AIMINGS Center will have a Computational Systems Core (CSC) that consists of both computational programming and modeling personnel that will serve all AIMINGS Center projects as well as the NPH Consortium and beyond. The West Point internal computing platforms are a shared resource in the CSC that allows for immediate model simulation and data processing across AIMINGS. Our CSC team has extensive experience in computational resources, security of controlled data, hardware and app development, computational model development in multiple programming languages and experience leading many different computational modeling and tool development projects. These resources (e.g., data storage, processing power, and compute time) will be available to all AIMINGS Center Cores and Projects, including the Pilot Projects. Aim 1 will provide shared computational and data resources to the AIMINGS Center Cores and Projects and NPH Consortium. Aim 2 will provide mathematical and computational modeling expertise and resources to support the activities of the AIMINGS Projects and the NPH Consortium. Aim 3 will provide expertise and resources in computational tool development and deployment to support the activities of the AIMINGS Projects and the NPH Consortium. The AIMINGS Computational Systems Core will bring multiple innovations, such as: (1) Integrating and implementing Department of Defense (DoD) computing power to address nutrition for precision health, (2) Bringing a new level of data security to nutrition for precision health, (3) Resources and expertise to create new collaborative platforms, and (4) Creating a new generation of hybrid, transdisciplinary researchers who have enough understanding both the computational and nutrition/health aspects of the work.