AIMDMB Shared Resource Core

摘要-计算系统核心（CSC） 正如管理和协调核心 (ACC) 研究战略中所述，该项目的愿景 拟议的 AIMINGS 中心旨在实施计算和数据科学方法和工具，以推进 营养精准健康。为了实现这一愿景，数据系统核心 (DSC)、四个项目、 试点项目、精准健康营养 (NPH) 联盟以及更大规模的精准营养研究 社区可以从一套集成且随时可用的专用计算资源中受益，并且 专业知识。为每个项目和核心单独提供此类资源可能会导致不必要的冗余 更重要的是错过了协同效应和机会。每个项目虽然能够作为独立的项目运行 项目，旨在促进和促进彼此。因此，一组中央计算资源和 专业知识将促进这种整合并共同努力。此外，单组更容易 资源和专业知识不仅适应项目的发展，而且适应可能需要的发展 对于 NPH 联盟和不断发展的新技术的出现。另外，这样一个 这种情况将使资源和人员从一个项目转移到另一个项目变得更加容易，从而提供跨项目 培训机会。因此，AIMINGS 中心将拥有一个计算系统核心 (CSC) 由计算编程和建模人员组成，将为所有目标服务 中心项目以及 NPH 联盟及其他项目。西点军校内部计算平台 是 CSC 中的共享资源，允许跨系统进行即时模型仿真和数据处理 目标。我们的 CSC 团队在计算资源、受控数据的安全性、 硬件和应用程序开发、多种编程语言的计算模型开发以及 拥有领导许多不同计算建模和工具开发项目的经验。这些资源 （例如，数据存储、处理能力和计算时间）将可供所有 AIMINGS 中心核心和 项目，包括试点项目。目标 1 将提供共享的计算和数据资源 AIMINGS 中心核心和项目以及 NPH 联盟。目标 2 将提供数学和 计算建模专业知识和资源，以支持 AIMINGS 项目和 NPH 财团。目标 3 将提供计算工具开发和 部署以支持 AIMINGS 项目和 NPH 联盟的活动。目标 计算系统核心将带来多项创新，例如：（1）集成和实施 国防部 (DoD) 解决营养问题以实现精准健康的计算能力，(2) 带来新的 数据安全水平到营养以实现精准健康，(3) 资源和专业知识以创建新的协作 平台，以及（4）创建新一代混合型、跨学科研究人员，他们拥有足够的资源 了解工作的计算和营养/健康方面。

Abstract-Computational Systems Core (CSC) As described in the Administration and Coordination Core (ACC) Research Strategy, the vision of this proposed AIMINGS Center is to implement computational and data science approaches and tools to advance nutrition for precision health. To accomplish this vision the Data Systems Core (DSC), the four projects, the pilot projects, the Nutrition for Precision Health (NPH) Consortium, and the larger precision nutrition research community could benefit from an integrated and readily available set of dedicated computational resources and expertise. Having separate such resources for each project and core could lead to unnecessary redundancy and more importantly missed synergies and opportunities. Each project, while able to function as a stand-alone project, is designed to facilitate and further each other. Thus, a central set of computational resources and expertise would facilitate this integration and work together. Moreover, it will be easier for a single set of resources and expertise to adapt to not only evolution of the projects but also evolution of what may be needed for the NPH consortium and the emergence of new technology, which continues to evolve. Additionally, such a situation will make it easier to shift resources and personnel from one project to another, providing cross- training opportunities. Thus, the AIMINGS Center will have a Computational Systems Core (CSC) that consists of both computational programming and modeling personnel that will serve all AIMINGS Center projects as well as the NPH Consortium and beyond. The West Point internal computing platforms are a shared resource in the CSC that allows for immediate model simulation and data processing across AIMINGS. Our CSC team has extensive experience in computational resources, security of controlled data, hardware and app development, computational model development in multiple programming languages and experience leading many different computational modeling and tool development projects. These resources (e.g., data storage, processing power, and compute time) will be available to all AIMINGS Center Cores and Projects, including the Pilot Projects. Aim 1 will provide shared computational and data resources to the AIMINGS Center Cores and Projects and NPH Consortium. Aim 2 will provide mathematical and computational modeling expertise and resources to support the activities of the AIMINGS Projects and the NPH Consortium. Aim 3 will provide expertise and resources in computational tool development and deployment to support the activities of the AIMINGS Projects and the NPH Consortium. The AIMINGS Computational Systems Core will bring multiple innovations, such as: (1) Integrating and implementing Department of Defense (DoD) computing power to address nutrition for precision health, (2) Bringing a new level of data security to nutrition for precision health, (3) Resources and expertise to create new collaborative platforms, and (4) Creating a new generation of hybrid, transdisciplinary researchers who have enough understanding both the computational and nutrition/health aspects of the work.