Sleep and Circadian Methods (SCM) Core

项目概要/摘要 COBRE儿童和青少年心理健康睡眠和昼夜节律中心的目标是 建立一个中心，帮助弥合睡眠和昼夜节律科学与儿童和青少年之间的差距， 心理健康睡眠和昼夜节律方法（SCM）核心的目标是支持项目负责人 和中心的研究人员在整个研究过程中适当使用睡眠和昼夜节律的方法。 睡眠和昼夜节律数据是复杂且多模态的，需要专业的专业知识来选择、获取、评分， 分析和解释。SCM核心将提供这方面的专业知识，以支持初级调查员的各个方面， 研究过程从研究设计开始，经过数据采集和数据质量控制 处理和结束于分析和解释。核心将支持调查人员在三个主要 域.首先，SCM核心将协助选择，获取，评分，分析和解释 睡眠和昼夜节律测量。这种援助将通过管理资源库（例如， 推荐阅读，研究协议，指南，评分说明，分析语法），提供专家 咨询和直接援助，利用训练有素的技术人员和研究学徒的时间。二是 核心将协调对设施、仪器、软件和数据库资源的访问， 睡眠和昼夜节律数据的采集、存储和评分。这种协调将使COBRE- 附属项目，利用有限的资源，如床在布拉德利睡眠实验室。最后，核心将 提供当前最佳做法方面的培训，并帮助确定创新方法、衡量和分析 适合儿童心理健康人群的睡眠和昼夜节律科学方法。通过这些 服务，SCM核心将大大提高布拉德利睡眠实验室的专业 基础设施和专业知识，迄今为止，只有那些直接受雇于 实验室长期目标是将儿科睡眠和昼夜节律方法整合到布拉德利医院 基础设施，从而提供一个持久的资源，将支持研究解决之间的相互作用 心理健康、发育、睡眠和昼夜节律。

Project Summary/Abstract The goal of the COBRE Center on Sleep and circadian rhythms in child and adolescent mental health is to build a center that will help bridge the gap between sleep and circadian science and child and adolescent mental health. The objective of the Sleep and Circadian Methods (SCM) Core is to support Project Leaders and Center investigators in the appropriate use of sleep and circadian methods across the research process. Sleep and circadian data are complex and multimodal, requiring specialized expertise to select, acquire, score, analyze and interpret. The SCM Core will provide this expertise to support junior investigators in all aspects of the research process starting at study design moving through data acquisition and quality control to data processing and ending at analysis and interpretation. The core will support investigators in three major domains. First, the SCM core will assist in the selection, acquisition, scoring, analysis, and interpretation of sleep and circadian measures. This assistance will be through curation of a resource library (e.g., recommended readings, research protocols, guides, scoring instructions, analytic syntax), provision of expert consultation, and direct assistance using time from trained technicians and research apprentices. Second, the core will coordinate access to facilities, instrumentation, software, and database resources required for acquisition, storage, and scoring of sleep and circadian data. This coordination will enable the COBRE- affiliated projects to utilize finite resources such as beds in the Bradley Sleep Laboratory. Finally, the core will provide training in current best-practices and help identify innovative methods, measurement and analytic approaches to sleep and circadian science suitable for pediatric mental health populations. Through these services, the SCM core will greatly enhance the reach of the Bradley Sleep Laboratory's specialized infrastructure and expertise, which to date have only been available to those directly employed by the laboratory. The Long-term goal is to integrate pediatric sleep and circadian methods into Bradley Hospital infrastructure thus providing an enduring resource that will support research addressing the interplay between mental health, development, sleep, and circadian rhythms.