Sleep and Circadian Methods (SCM) Core

睡眠和昼夜节律方法 (SCM) 核心

• 批准号: 10594995
• 负责人: DAVID Heaton BARKER
• 金额: $ 48.51万
• 依托单位: EMMA PENDLETON BRADLEY HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-06 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10594995
• 关键词: Address; Adolescent; Beds; Calibration; Centers of Research Excellence; Child; Childhood; Circadian Rhythms; Computer software; Consultations; Data; Data Storage and Retrieval; Databases; Development; Drowsiness; Goals; Grant; Health Insurance Portability and Accountability Act; Hospitals; Infrastructure; Institutional Review Boards; Instruction; International; Laboratories; Language; Libraries; Light; Lighting; Measurement; Measures; Mental Health; Methodology; Methods; Monitor; Phase; Physiology; Polysomnography; Process; Protocols documentation; Quality Control; Recommendation; Recording of previous events; Research; Research Design; Research Personnel; Research Support; Resources; Science; Services; Sleep; Staging; Structure; Surveys; Training; Training Programs; Visual; actigraphy; apprenticeship; circadian; complex data; computerized data processing; contextual factors; data acquisition; data quality; diaries; human subject; innovation; instrument; instrumentation; interest; multidisciplinary; multimodality; novel; population health; pressure; programs; quality assurance; sleep behavior; sleep regulation; social; syntax; theories; time use; training opportunity; wearable device; working group

Project Summary/Abstract The goal of the COBRE Center on Sleep and circadian rhythms in child and adolescent mental health is to build a center that will help bridge the gap between sleep and circadian science and child and adolescent mental health. The objective of the Sleep and Circadian Methods (SCM) Core is to support Project Leaders and Center investigators in the appropriate use of sleep and circadian methods across the research process. Sleep and circadian data are complex and multimodal, requiring specialized expertise to select, acquire, score, analyze and interpret. The SCM Core will provide this expertise to support junior investigators in all aspects of the research process starting at study design moving through data acquisition and quality control to data processing and ending at analysis and interpretation. The core will support investigators in three major domains. First, the SCM core will assist in the selection, acquisition, scoring, analysis, and interpretation of sleep and circadian measures. This assistance will be through curation of a resource library (e.g., recommended readings, research protocols, guides, scoring instructions, analytic syntax), provision of expert consultation, and direct assistance using time from trained technicians and research apprentices. Second, the core will coordinate access to facilities, instrumentation, software, and database resources required for acquisition, storage, and scoring of sleep and circadian data. This coordination will enable the COBRE- affiliated projects to utilize finite resources such as beds in the Bradley Sleep Laboratory. Finally, the core will provide training in current best-practices and help identify innovative methods, measurement and analytic approaches to sleep and circadian science suitable for pediatric mental health populations. Through these services, the SCM core will greatly enhance the reach of the Bradley Sleep Laboratory's specialized infrastructure and expertise, which to date have only been available to those directly employed by the laboratory. The Long-term goal is to integrate pediatric sleep and circadian methods into Bradley Hospital infrastructure thus providing an enduring resource that will support research addressing the interplay between mental health, development, sleep, and circadian rhythms.

项目概要/摘要 COBRE 儿童和青少年心理健康睡眠和昼夜节律中心的目标是 建立一个中心，帮助弥合睡眠和昼夜节律科学与儿童和青少年之间的差距 心理健康。睡眠和昼夜节律方法 (SCM) 核心的目标是支持项目负责人 中心研究人员在整个研究过程中适当使用睡眠和昼夜节律方法。 睡眠和昼夜节律数据是复杂的、多模式的，需要专门的专业知识来选择、获取、评分、 分析和解释。 SCM 核心将提供专业知识来支持初级研究人员的各个方面 研究过程从研究设计开始，经过数据采集和质量控制直至数据 处理并以分析和解释结束。该核心将支持三个主要领域的调查人员 域。首先，SCM核心将协助选择、获取、评分、分析和解释 睡眠和昼夜节律措施。这种援助将通过资源库的管理（例如， 推荐读物、研究方案、指南、评分说明、分析语法）、提供专家 咨询，并利用训练有素的技术人员和研究学徒的时间提供直接帮助。其次， 核心将协调对所需设施、仪器、软件和数据库资源的访问 睡眠和昼夜节律数据的采集、存储和评分。这种协调将使 COBRE- 利用布拉德利睡眠实验室床位等有限资源的附属项目。最后，核心将 提供当前最佳实践的培训，并帮助确定创新方法、测量和分析 适合儿科心理健康人群的睡眠和昼夜节律科学方法。通过这些 服务，SCM 核心将大大增强布拉德利睡眠实验室专业服务的覆盖范围 基础设施和专业知识，迄今为止仅向直接受雇于该机构的人员提供 实验室。长期目标是将儿科睡眠和昼夜节律方法纳入布拉德利医院 基础设施因此提供了持久的资源，支持解决之间相互作用的研究 心理健康、发育、睡眠和昼夜节律。