Identification and modulation of insula to BNST circuit specific afferents in ethanol abstinence
Identification and modulation of insula to BNST circuit specific afferents in ethanol abstinence
批准号:
10387911
负责人:
Joseph Richard Luchsinger
金额:
$0.25万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-04-08 至 2022-06-30
关键词:
2-arachidonylglycerolAbstinenceAcuteAlcohol consumptionAlcohol dependenceAlcohol withdrawal syndromeAlcoholismAlcoholsAmphetamine AddictionAnimalsAnteriorAnxiety DisordersAttentionBackBiologicalBirthBrain regionBudgetsCNR1 geneCalcium SignalingCellsChronicCountryDataEconomicsElectrophysiology (science)EndocannabinoidsEthanolEventExerciseExtended FamilyFamilyFathersFiberFinancial HardshipFlying body movementFundingGoalsGrantHomeHourInsula of ReilInvestigationLabelLifeLipidsLoveMethodsMorbidity - disease rateMotorMotor CortexMusNeuronsNicotine DependenceOutputParentsPathway interactionsPatientsPharmacologyPhenotypePhotometryPhysiciansPhysiologyPopulationProcessPropertyRecurrent diseaseRelapseReportingResearchResourcesRestRoleRunningScienceScientistSignal TransductionSonStimulusStressStructure of terminal stria nuclei of preoptic regionSynapsesSynaptic TransmissionTechniquesTestingTimeTracerTrainingViralWagesWifeWithdrawalWorkaddictionalcohol abstinencealcohol effectalcohol exposurealcohol use disorderanandamidebiological adaptation to stresscomorbiditycoronavirus diseasecosteconomic costendocannabinoid signalingendogenous cannabinoid systemexperienceexperimental studyfamily supportfeedinggraduate studenthuman imagingimaging modalityimaging studyin vivomortalitynegative affectneural circuitneuromechanismnovelphysical symptompostsynapticpreventproblem drinkerresponseskillssocialstressortransmission process
中文摘要
项目摘要
我是一个幸运的父亲,有一个充满快乐的11个月大的儿子。很难捕捉到他的爱
但他的出生给我们带来了额外的压力特别是
我们新家庭的经济负担很重。我妻子全职工作养家
我就可以离开了我的大家庭不住在我们州,我妻子的
她的家人回到了她的祖国,这意味着我们在很大程度上是独自飞行。我们与世隔绝
家庭的支持使可靠和方便的日托对我的能力是必要的,
科学有几天日托中心关闭(由于新冠肺炎)。期间
那一次,我的儿子呆在家里,我成了一个全职父母。它清楚地说明了
如何必要的儿童保育是我的能力,继续工作,以更好地了解
压力和成瘾的神经回路。不幸的是,即使在今年,我们
看到托儿费用继续上升,从一个毕业生已经感到几乎负担不起
学生的工资。这笔费用给我们的预算带来了很大的压力。为儿童保育费用提供资金
将帮助我们抵消这些成本,并让我更有效地工作,以实现该项目的
最初的目标。
英文摘要
PROJECT SUMMARY
I am the lucky father to a joy-filled eleven-month-old son. It is hard to capture the love he has
brought into our family’s life, yet his birth has come with additional stressors. Notably, the
financial burden on our new family is significant. My wife works full-time to support the family
while I complete my training. My extended family does not live in our state, and my wife’s
family is back in her home country, meaning we are largely flying solo. Our seclusion from
familial support has made reliable and accessible daycare a necessity to my ability to do
science. There have been days on which daycare was closed (due to Covid exposure). During
that time, my son stayed home, and I became a full-time parent. It proved a stark illustration of
how necessary childcare is to my ability to continue working to better understand the
neurocircuitry involved in stress and addiction. Unfortunately, even within this year, we have
seen childcare costs continue to rise from what already felt barely affordable on a graduate
student’s salary. This cost puts significant strain on our budget. Funding for childcare expenses
will help us offset those costs and allow me to work more effectively to achieve the project’s
original aims.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Identification and modulation of insula to BNST circuit specific afferents in ethanol abstinence
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批准号:10196888
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项目类别:
-
资助金额:$4.83万
-
财政年份:2019
-
负责人:Joseph Richard Luchsinger
-
依托单位:
Identification and modulation of insula to BNST circuit specific afferents in ethanol abstinence
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批准号:9757511
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项目类别:
-
资助金额:$2.98万
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财政年份:2019
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负责人:Joseph Richard Luchsinger
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依托单位:
海外基金