Optimizing health from pregnancy through one year postpartum: A sequential multiple assignment randomized trial (SMART) of perinatal lifestyle intervention
Optimizing health from pregnancy through one year postpartum: A sequential multiple assignment randomized trial (SMART) of perinatal lifestyle intervention
批准号:
10392312
负责人:
MICHELE D LEVINE
金额:
$36.84万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-09-13 至 2024-06-30
关键词:
AddressAdministrative SupplementAffectAreaAttenuatedBehaviorBehavioralBehavioral trialBody mass indexCOVID-19COVID-19 pandemicCaringData CollectionDietary intakeDiscriminationExposure toFaceFoodGoalsGrantHealthHealth behaviorInterventionMaternal HealthMeasuresMental HealthModelingMoodsMothersObesityOutcomeOverweightParentsPennsylvaniaPerinatalPersonal SatisfactionPhysical activityPostpartum PeriodPregnancyPregnant WomenPsychosocial StressReportingResearchRiskRoleSamplingSequential Multiple Assignment Randomized TrialSleepSocial EnvironmentStressStructural RacismUnited States National Institutes of HealthWeightWomanWomen&aposs Healthadverse maternal outcomesbiopsychosocialblack womencomparison interventiondepressive symptomsevidence basefood insecurityimprovedlifestyle interventionmaternal weightneonatal outcomenovelpandemic diseaseperinatal healthperinatal interventionperinatal periodpregnantprepregnancypsychoeducationpsychosocialracial discriminationracial health disparityracismrandomized trialrecruitresponsestress managementstressortreatment as usual
中文摘要
摘要
我们目前正在招募超重/肥胖的女性(孕前体重指数≥25)
一项为期两个阶段的生活方式干预的随机试验
产后一年(R01HL132578)。回应NOT-OD-21-071《行政补充和紧急事项》
对美国国立卫生研究院拨款的竞争性修订,以增加或扩大专注于孕产妇健康、结构性研究的研究
种族主义与歧视(SRD)和新冠肺炎,“我们建议加强我们正在进行的审判的目标
围产期生活方式干预,“优化孕期到产后一年的健康:A
围产期生活方式干预的序贯多重分配随机试验[SMART]
新冠肺炎大流行与结构性种族主义和歧视(SRD)
影响围产期健康和心理健康。我们建议通过几种方式加强我们正在进行的试验的目标。
首先,我们旨在评估新冠肺炎大流行对体重、体重相关行为的影响,
孕前超重/肥胖妇女的抑郁症状和心理社会压力
怀孕至产后6个月,并检查行为和心理社会干预的可能性
在围产期分娩,以减轻大流行对产妇健康的负面影响
心理健康。第二,我们建议增加对粮食不安全和种族歧视的评估。给定
新冠肺炎疫情对黑人女性健康的不成比例影响,我们将通过以下方式增加样本
再招募40名黑人孕妇(孕前体重指数≥25)。增加了对食品的评估
不安全感和歧视将补充饮食摄入量、体力活动、抑郁
在父母R01中收集的症状、心理社会压力、睡眠和体重。干预组件,如
如心理教育、指导、目标设定和与健康行为促进、情绪和支持相关的支持
压力管理可以应对与大流行相关的压力源,以及无数的挑战和担忧
女性在怀孕和产后都要面对。本补编的目的是:(1)审查
新冠肺炎大流行对体重、体重相关行为、抑郁症状和心理社会压力的影响
在怀孕结束和产后6个月超重/肥胖的妇女;(2)确定
围产期生活方式干预可减轻与大流行相关的体重、体重相关的负面影响
行为和心理健康;以及(3)评估与以下方面有关的粮食不安全和感觉到的歧视
母亲体重、心理健康结果和生活方式干预反应。因此,我们的目标是利用
正在进行的R01通过记录潜在的生活方式来为改善护理提供证据基础
减轻新冠肺炎疫情对围产期孕产妇健康和心理的负面影响的干预措施
健康。
英文摘要
ABSTRACT
We are currently recruiting women with overweight/obesity (prepregnancy BMI ≥ 25) at the beginning of
pregnancy into a two-stage randomized trial of lifestyle interventions delivered across pregnancy and the first
year postpartum (R01HL132578). In response to NOT-OD-21-071 “Administrative Supplements and Urgent
Competitive Revisions for NIH Grants to Add or Expand Research Focused on Maternal Health, Structural
Racism and Discrimination (SRD), and COVID-19,” we propose to enhance the aims of our ongoing trial of
perinatal lifestyle interventions, “Optimizing Health from Pregnancy through One Year Postpartum: A
Sequential Multiple Assignment Randomized Trial [SMART] of Perinatal Lifestyle Intervention” to address
questions about the ways in which the COVID-19 pandemic and structural racism and discrimination (SRD)
affect perinatal health and mental health. We propose to enhance the aims of our ongoing trial in several ways.
First, we aim to evaluate the effects of the COVID-19 pandemic on weight, weight-related behaviors,
depressive symptoms, and psychosocial stress among women with prepregnancy overweight/obesity from
pregnancy to 6 months postpartum and examine the potential for behavioral and psychosocial intervention
delivered during the perinatal period to attenuate negative effects of the pandemic on maternal health and
mental health. Second, we propose to add assessments of food insecurity and racial discrimination. Given the
disproportionate effects of the COVID-19 pandemic on Black women’s health, we will enhance our sample by
recruiting 40 additional Black pregnant women (prepregnancy BMI ≥ 25). The added assessments of food
insecurity and discrimination will supplement measures of dietary intake, physical activity, depressive
symptoms, psychosocial stress, sleep, and weight collected in the parent R01. Intervention components such
as psychoeducation, coaching, goal-setting, and support related to health behavior promotion, mood and
stress management can address stressors related to the pandemic, and the myriad challenges and concerns
women face during pregnancy and postpartum. The aims of this supplement are to: (1) Examine the impact of
the COVID-19 pandemic on weight, weight-related behaviors, depressive symptoms, and psychosocial stress
in women with overweight/obesity at the end of pregnancy and 6 months postpartum; (2) Determine whether
perinatal lifestyle intervention attenuates negative pandemic-related effects on weight, weight-related
behaviors and mental health; and (3) Evaluate food insecurity and perceived discrimination in relation to
maternal weight, mental health outcomes, and lifestyle intervention response. Thus, we aim to leverage the
ongoing R01 to contribute an evidence base to improve care by documenting the potential for lifestyle
intervention to attenuate negative impacts of the COVID-19 pandemic on perinatal maternal health and mental
health.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Taste manipulation during a food cue-reactivity task: Effects on cue-elicited food craving and subsequent food intake among individuals with overweight and obesity.
食物提示反应任务期间的味觉操纵:对超重和肥胖个体中提示引起的食物渴望和随后的食物摄入的影响。
DOI:
10.1016/j.eatbeh.2019.03.005
发表时间:
2019
期刊:
Eating behaviors
影响因子:
2.8
作者:
[Germeroth,LisaJ, Wallace,MeredithL, Levine,MicheleD]
通讯作者:
Levine,MicheleD
The role of impulsive phenotypes on weight trajectories and response to behavioral interventions during pregnancy and the postpartum period
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批准号:9906930
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项目类别:
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资助金额:$44.4万
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财政年份:2018
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依托单位:
The role of impulsive phenotypes on weight trajectories and response to behavioral interventions during pregnancy and the postpartum period
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财政年份:2018
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Optimizing health from pregnancy through one year postpartum: A sequential multiple assignment randomized trial (SMART) of perinatal lifestyle intervention
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财政年份:2016
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Optimizing health from pregnancy through one year postpartum: A sequential multiple assignment randomized trial (SMART) of perinatal lifestyle intervention
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批准号:9195238
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资助金额:$74.37万
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财政年份:2016
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Optimizing health from pregnancy through one year postpartum: A sequential multiple assignment randomized trial (SMART) of perinatal lifestyle intervention
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资助金额:$69.66万
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Relationship of Loss of Control Eating to Excessive Gestational Weight Gain
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批准号:8434025
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Relationship of Loss of Control Eating to Excessive Gestational Weight Gain
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批准号:8620675
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资助金额:$40.82万
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财政年份:2012
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依托单位:
Relationship of Loss of Control Eating to Excessive Gestational Weight Gain
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批准号:8234408
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资助金额:$40.42万
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财政年份:2012
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Relationship of Loss of Control Eating to Excessive Gestational Weight Gain
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批准号:8815956
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资助金额:$40.8万
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财政年份:2012
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负责人:MICHELE D LEVINE
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Relationship of Loss of Control Eating to Excessive Gestational Weight Gain
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批准号:9026631
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资助金额:$39.28万
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依托单位:
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财政年份:2007
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负责人:MICHELE D LEVINE
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依托单位:
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批准号:7659689
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项目类别:
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资助金额:$52.66万
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财政年份:2007
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负责人:MICHELE D LEVINE
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依托单位:
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批准号:8079502
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项目类别:
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资助金额:$50.73万
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财政年份:2007
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负责人:MICHELE D LEVINE
-
依托单位:
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-
批准号:7841721
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项目类别:
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资助金额:$53.6万
-
财政年份:2007
-
负责人:MICHELE D LEVINE
-
依托单位:
Addressing Postpartum Mood and Weight Concerns to Sustain Smoking Cessation
-
批准号:7370724
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项目类别:
-
资助金额:$49.37万
-
财政年份:2007
-
负责人:MICHELE D LEVINE
-
依托单位:
Treating Postpartum Nicotine Dependence
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批准号:7093583
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项目类别:
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资助金额:$11.63万
-
财政年份:2002
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负责人:MICHELE D LEVINE
-
依托单位:
Treating Postpartum Nicotine Dependence
-
批准号:6920037
-
项目类别:
-
资助金额:$12.24万
-
财政年份:2002
-
负责人:MICHELE D LEVINE
-
依托单位:
Treating Postpartum Nicotine Dependence
-
批准号:6768827
-
项目类别:
-
资助金额:$11.32万
-
财政年份:2002
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负责人:MICHELE D LEVINE
-
依托单位:
Treating Postpartum Nicotine Dependence
-
批准号:6667098
-
项目类别:
-
资助金额:$11.57万
-
财政年份:2002
-
负责人:MICHELE D LEVINE
-
依托单位:
Treating Postpartum Nicotine Dependence
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批准号:6508803
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项目类别:
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资助金额:$10.77万
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海外基金