Integrated Health Sciences Facility Core

IHSFC项目总结 在新墨西哥州，采矿、金属和金属开采对健康的影响(包括个人和社区) 暴露以及石油/天然气/水力压裂活动是社区非常关注的问题。有很大范围的 研究人员和研究团队中存在的经验和广泛的知识深度 在整个NM-激励中心的调查人员，可以被引导到解决这些社区 环境健康问题。IHSFC的总体目标是与所有中心的 核心，并提供关键基础设施和支持，以实施创新的转换和反向 为新墨西哥州社区服务的翻译性环境健康研究。环境 目前由NM-Inspirates进行的健康研究产生了大量关于 变量包括环境暴露、中间生物反应和复杂的健康 结果。正在进行的广泛的环境、人类和动物研究的结果提供了一个 丰富的数据来源，为解决复杂问题提供信息和启发新的翻译或反向翻译研究 暴露-结果关系。IHSFC将支持扩展和实施新的 翻译和反向翻译研究，并利用存在于 中心。IHSFC团队包括流行病学、公共卫生和毒理学方面的专业知识，以提供指导 用于研究设计，以有效地处理人口风险因素和易感性以及潜在的 推动健康结果的机制。具体地说，IHSFC将提供特殊和补充 通过1)提供科学、技术和运营支持，以促进新的协作和计划 为人口、临床和实验室研究的研究设计和实施提供支持，2) 克服体制或监管瓶颈，3)便利获取现有数据和样本 正在进行的环境研究，以支持或验证新的倡议。中的特定体验 IHSFC团队在实施翻译研究方面将提供一个不 目前存在于整个中心。IHSFC将努力利用独特的研究背景和 新墨西哥州管理中心的经验启发我们在新墨西哥州更广泛地扩展我们的触角，并建立 凭借现有的专业知识、可用资源发展基础设施并创造价值- 增加了将实现中心目标的协同服务。由提供的服务和支持 IHSFC提供了一种机制，以继续扩大我们优秀的基础和翻译研究项目 在环境健康方面为我们多样化的社区服务。

IHSFC PROJECT SUMMARY Within the state of New Mexico, the health impacts (both individual and communal) from mining, metal exposure as well as oil/gas/fracking activities are of considerable community concern. There is a broad range of experience and extensive depth of knowledge that exists among the researchers and research teams throughout the NM-INSPIRES Center investigators that can be directed toward addressing these community environmental health concerns. The overall goal of the IHSFC is to work in partnership with all the Center’s Cores and provide key infrastructure and support to actualize innovative translational and reverse translational environmental health research that serves the communities of New Mexico. Environmental health research currently conducted by NM-INSPIRES investigators generates data on a large number of variables including environmental exposures, intermediate biological responses, and complex health outcomes. The findings from this broad array of ongoing environmental, human and animal studies provides a rich source of data to inform and inspire new translational or reverse-translational studies addressing complex exposure-outcome relationships. The IHSFC will support the expansion and implementation of new translational and reverse-translational research and capitalizes on the broad experience that exists within the Center. The IHSFC team includes expertise in epidemiology, public health and toxicology to provide guidance for study design to effectively address population risk factors and susceptibilities as well as potential mechanisms that drive health outcomes. Specifically, the IHSFC will provide exceptional and complementary scientific, technical and operational support to facilitate both new collaborations and initiatives through 1) providing support for study design and implementation of population, clinical and laboratory based studies, 2) overcoming institutional or regulatory bottlenecks, 3) facilitating access to existing data and samples from ongoing environmental research to support or validate new initiatives. The specific experience within the IHSFC team in implementing translational research studies will provide an infrastructure that does not currently exist across the Center. The IHSFC will work to capitalize on the unique research background and experience within the NM INSPIRES Center to expand our reach more broadly across New Mexico and build on the strength of existing expertise, available resources to develop the infrastructure and create a value- added synergistic service that will achieve Center objectives. The services and support provided by the IHSFC provides a mechanism to continue to expand our excellent basic and translational research programs in environmental health to serve our diverse community.