P and F Program

试点和可行性计划 摘要/摘要 试点和可行性计划(P&F)是加州大学丹佛分校DRC的一个关键组成部分，它将允许DRC 领导力：1)为糖尿病研究招募新的人才；2)从其他领域吸引成熟的研究人员 3)支持创新/高危糖尿病研究 项目。我们的首要任务是得到科罗拉多大学新独立的年轻研究人员的支持 Anschutz医学院(UC AMC)及其附属机构，他们正在着手糖尿病研究 职业发展，但尚未获得大量资金。此外，加州大学丹佛分校的P&F计划是一个重要的 通过促进糖尿病研究中心成员之间的合作促进跨学科糖尿病研究的手段 改善DRC成员与加州大学丹佛NIH中心或院长之间的大学范围内的互动 首创精神。P&F计划还将作为一种机制，增加UC AMC糖尿病患者的多样性 研究社区及其研究档案袋。我们将通过以下具体目标实现这些目标： 目标1：建立一个透明和精简的赠款征集、科学审查、供资、项目 指导/管理和进度评估。 目标2：通过以下方式加强UC AMC糖尿病研究社区并使其创新研究组合多样化 向：a)缺乏大量研究经费的早期职业糖尿病研究人员提供资金；b)建立 来自其他领域的研究人员打算将他们的知识和专业知识应用于糖尿病的调查- 相关主题(S)；c)建立糖尿病研究人员，他们提出偏离常理的创新、高风险项目 从他们目前资助的研究项目中，这不太可能通过通常的拨款来提供资金 没有令人信服的初步数据的机构；d)开发新的模型(即有机化合物)以检查独特的 生理指标，如性别，作为生物变量和免疫调节。 目标3：为P&F资助的研究人员提供职业指导和科学之家。 目标4：正式评估加州大学丹佛分校P&F计划对个人赠款接受者的影响，如 以及整个加州大学AMC糖尿病研究社区的研究。

PILOT AND FEASIBILITY PROGRAM SUMMARY/ABSTRACT The Pilot and Feasibility Program (P&F) is a key component of the UC Denver DRC that will allow DRC leadership to: 1) recruit new talent into diabetes research, 2) attract established investigators from other disciplines into diabetes-related scientific pursuits, and 3) support innovative/high-risk diabetes research projects. Our priority is the support of young, newly independent investigators at the University of Colorado Anschutz Medical Campus (UC AMC), and its affiliated institutions, who are embarking on diabetes research careers, but have yet to attain substantial funding. In addition, the UC Denver DRC P&F Program is an important means of promoting interdisciplinary diabetes research by fostering collaboration between DRC members and improving university-wide interactions between DRC members and other UC Denver NIH Centers or Dean’s Initiatives. The P&F program will also serve as a mechanism to increase the diversity of the UC AMC diabetes research community and its research portfolio. We will achieve these goals through the following specific aims: AIM 1: To establish a transparent and streamlined process for grant solicitation, scientific review, funding, project guidance/management, and progress assessment. AIM 2: To enhance the UC AMC diabetes research community and diversify its innovative research portfolio by providing funding to: a) early career diabetes investigators who lack substantial research funding; b) established investigators from other fields that intend to apply their knowledge and expertise to investigation of diabetes- related topic(s); c) established diabetes investigators who propose innovative, high-risk projects that deviate from their current funded research programs, and that would be unlikely to be funded through the usual granting agencies without compelling preliminary data; d) develop novel models (i.e. organoids) to examine unique physiological targets such as sex as a biological variable and immunomodulation. AIM 3: To provide career guidance and a scientific home for P&F funded investigators. AIM 4: To formally evaluate the impact of the UC Denver DRC P&F Program on individual grant recipients, as well as on the UC AMC diabetes research community as a whole.