P and F Program

试点和可行性研究 总结/摘要 试点和可行性计划（P&F）是UC Denver DRC的关键组成部分，将允许DRC 领导力：1）招募新的人才进入糖尿病研究，2）吸引来自其他领域的知名研究人员 3）支持创新/高风险糖尿病研究 项目我们的首要任务是得到科罗拉多大学年轻的、新近独立的调查人员的支持 安舒茨医学院（UC AMC）及其附属机构，他们正在进行糖尿病研究 职业生涯，但尚未获得大量资金。此外，UC Denver DRC P&F计划是一个重要的 通过促进DRC成员之间的合作来促进跨学科糖尿病研究的方法， 改善DRC成员和其他UC Denver NIH中心或院长之间的大学范围内的互动 举措P&F计划还将作为一种机制，以增加UC AMC糖尿病的多样性 研究社区及其研究组合。我们将通过以下具体目标实现这些目标： 目标1：建立一个透明和精简的程序，用于赠款征集、科学审查、资助、项目 指导/管理和进度评估。 目的2：通过以下方式加强UC AMC糖尿病研究社区并使其创新研究组合多样化 提供资金给：a）缺乏大量研究资金的早期糖尿病研究人员; B）建立 来自其他领域的研究人员，他们打算将自己的知识和专业知识应用于糖尿病的研究， 相关主题; c）已建立的糖尿病研究人员，他们提出了创新的，高风险的项目， 从他们目前资助的研究项目中，这不太可能通过通常的拨款来资助。 机构没有令人信服的初步数据; d）开发新的模型（即类器官），以检查独特的 生理目标，如作为生物变量的性别和免疫调节。 目标3：为P&F资助的研究人员提供职业指导和科学家。 目的4：正式评估加州大学丹佛分校DRC P&F计划对个人赠款接受者的影响， 以及整个UC AMC糖尿病研究社区。

PILOT AND FEASIBILITY PROGRAM SUMMARY/ABSTRACT The Pilot and Feasibility Program (P&F) is a key component of the UC Denver DRC that will allow DRC leadership to: 1) recruit new talent into diabetes research, 2) attract established investigators from other disciplines into diabetes-related scientific pursuits, and 3) support innovative/high-risk diabetes research projects. Our priority is the support of young, newly independent investigators at the University of Colorado Anschutz Medical Campus (UC AMC), and its affiliated institutions, who are embarking on diabetes research careers, but have yet to attain substantial funding. In addition, the UC Denver DRC P&F Program is an important means of promoting interdisciplinary diabetes research by fostering collaboration between DRC members and improving university-wide interactions between DRC members and other UC Denver NIH Centers or Dean’s Initiatives. The P&F program will also serve as a mechanism to increase the diversity of the UC AMC diabetes research community and its research portfolio. We will achieve these goals through the following specific aims: AIM 1: To establish a transparent and streamlined process for grant solicitation, scientific review, funding, project guidance/management, and progress assessment. AIM 2: To enhance the UC AMC diabetes research community and diversify its innovative research portfolio by providing funding to: a) early career diabetes investigators who lack substantial research funding; b) established investigators from other fields that intend to apply their knowledge and expertise to investigation of diabetes- related topic(s); c) established diabetes investigators who propose innovative, high-risk projects that deviate from their current funded research programs, and that would be unlikely to be funded through the usual granting agencies without compelling preliminary data; d) develop novel models (i.e. organoids) to examine unique physiological targets such as sex as a biological variable and immunomodulation. AIM 3: To provide career guidance and a scientific home for P&F funded investigators. AIM 4: To formally evaluate the impact of the UC Denver DRC P&F Program on individual grant recipients, as well as on the UC AMC diabetes research community as a whole.