Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)

密歇根生命阶段环境暴露和疾病中心 (M-LEEaD)

• 批准号: 10393183
• 负责人: Dana Dolinoy
• 金额: $ 54.33万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10393183
• 关键词: Address; Advisory Committees; Advocacy; Applications Grants; Basic Science; Budgets; COVID-19; Clinical; Collaborations; Communication; Communities; Consultations; Core Facility; Data; Disclosure; Disease; Elements; Ensure; Environmental Exposure; Environmental Hazards; Environmental Health; Environmental Impact; Evaluation; Event; Faculty; Feedback; Focus Groups; Fostering; Funding Opportunities; Goals; Grant; Health; Individual; International Aspects; Internet; Knowledge; Leadership; Learning; Life; Mentors; Michigan; Mission; National Institute of Environmental Health Sciences; Outcome; Patients; Performance; Pilot Projects; Policy Maker; Process; Program Development; Program Evaluation; Public Health; Publications; Records; Reporting; Research; Research Activity; Research Personnel; Research Training; Science; Scientist; Structure; Technology; Toxicology; Translational Research; Translations; Vision; Visit; Work; career; career development; climate change; climate-related health; community based participatory research; community engagement; efficacy evaluation; health disparity; high standard; human disease; improved; innovation; meetings; member; population health; practical application; programs; public health intervention; research and development; response; service programs; skills; symposium; theories; tool; translational research program

SUMMARY/ABSTRACT (Administrative Core) The Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) mission has two overarching goals: to accelerate research that defines and explains impacts of environmental exposures during vulnerable stages of life, and to promote translation of these findings to improve clinical and public health interventions for the mitigation of human disease. We implement our mission through integrated research, training, and community engagement overseen by the Administrative Core. The Core is led by Center Director Dolinoy with assistance from Deputy Director Meeker. This Core is the administrative unit for the Pilot Project Program (led by Meeker), Career Development Program (led by Associate Director Omenn), and Translational Research Program (led by Associate Director Padmanabhan). Research Teams (Cumulative Exposures & Population Health; Climate Change & Health Disparities; and Toxicological Mechanisms & Health Outcomes) are elements of the Translational Research Program with team leaders included as members of the Administrative Core. The teams embrace goals set forth in the NIEHS Translational Research Framework to enhance our Center’s translation of basic research into practical applications for patients and communities and serve as a mechanism for members to explore collaborations and coordinate funding opportunity responses. Inclusion of leadership of the Pilot Project, Career Development, and Translational Research programs in the core addresses the Center objective that these programs operate in an integrative manner. Additionally, the leader of the Community Engagement Core (CEC) is a member of the Core, and the citizen co-chair of the CEC Stakeholder Advocacy Board is a member of the Core’s Internal Advisory Committee. Core faculty are assisted by an administrative assistant, web designer, and evaluator. The Core is responsible for organizing M- LEEaD activities such as meetings, retreats, seminars, and focus groups, and maintaining records of reports, minutes, and evaluation results from such events. In addition, the Core provides fiduciary oversight of the budgets. The Core obtains and considers input on emerging theories, paradigms, and technologies in environmental health sciences and biomedicine at multiple levels, from Research Team reports to director meetings to Internal and External Advisory committees. The Core ensures that activities encourage innovative research for all members, but especially for early-stage investigators, and foster community engagement via multi-directional dialogue among M-LEEaD scientists, community members, and regulatory stakeholders. The Core coordinates responses to urgent environmental concerns, including interactions with other core centers, NIEHS, and relevant organizations. Finally, the Core is responsible for evaluation of the efficacy of M-LEEaD programs, cores, and activities, taking corrective action as warranted. Through this leadership, the Administrative Core ensures a high standard of activities for the translation of basic research findings into practical applications to advance a comprehensive and integrated environmental health paradigm.

摘要/摘要(管理核心) 密歇根生命环境暴露和疾病中心(M-LEEAD)任务有两个 首要目标：加快研究，定义和解释环境暴露的影响 促进这些研究成果的转化，以改善临床和公共卫生 减轻人类疾病的干预措施。我们通过综合研究来执行我们的使命， 培训，以及由行政核心监督的社区参与。核心由中心主任领导 多利诺伊在米克副局长的协助下。该核心是试点项目的行政单位 计划(由Meeker领导)、职业发展计划(由副主任Omenn领导)和翻译 研究计划(由副主任Padmanabhan领导)。研究团队(累积曝光量和 人口健康；气候变化和健康差异；毒理学机制和健康结果) 是翻译研究计划的要素，团队负责人包括在 管理核心。这些团队接受NIEHS翻译研究框架中提出的目标，以 加强我们中心将基础研究转化为患者和社区的实际应用 作为成员探索协作和协调资金机会响应的机制。 将试点项目、职业发展和翻译研究项目的领导力纳入 CORE致力于中心的目标，即这些项目以综合的方式运作。此外， 社区参与核心(CEC)的领导人是核心的成员，公民是 CEC利益相关者倡导委员会是核心的内部咨询委员会的成员。核心教员是 由一名行政助理、网页设计师和评估员协助。核心负责组织M- 领导会议、务虚会、研讨会、焦点小组等活动，维护报告记录， 会议纪要和此类活动的评估结果。此外，该核心提供受托监督 预算。核心获取并考虑对新兴理论、范例和技术的投入 多层次的环境健康科学和生物医学，从研究小组报告到主任 参加内部和外部咨询委员会的会议。核心确保活动鼓励创新 为所有成员进行研究，特别是针对早期调查人员，并通过以下方式促进社区参与 M-Lead科学家、社区成员和监管利益相关者之间的多方向对话。这个 核心协调对紧急环境问题的反应，包括与其他核心中心的互动， NIEHS和相关组织。最后，核心负责评估M-LEAD的疗效 计划、核心和活动，并采取必要的纠正措施。通过这一领导层， 管理核心确保将基础研究成果转化为 实际应用，以推进全面和综合的环境健康范例。