Advanced Immunobiology Traning Program for Surgeons

项目摘要/摘要 免疫生物学已经变得越来越与外科实践相关，影响着不同的学科，包括 肿瘤学、炎症性肠病、移植、创伤和危重护理。尽管这一点很重要 免疫操作已经成为外科实践的一个明显的辅助手段，外科培训既不包括 高级免疫学也不会让外科科学家做好参与免疫相关研究的准备。这次培训 拨款申请寻求拨款成立高级免疫生物学训练计划(AITP)，网址为 杜克大学将培养能够参与和领导与外科相关的领域的外科科学家 免疫生物学研究。培训计划将结合公爵在学术上的严谨 大学医学院与杜克大学外科系的合作由来已久，非常成功 致力于培养下一代外科研究人员。该节目将由一位 一名学术外科医生和一名基础科学研究员，每个人都有免疫学方面的专业知识。补充： 作为在基础、翻译和临床研究方面拥有专业知识的导师，这个多学科团队是独一无二的 有资格将基础和应用免疫生物学与不断发展的外科实践相结合。计划参与者将 由完成医学院学业并开始外科实习的博士后实习生组成。至少 在拟议的筹资期间，将对6名人员进行培训。基于个人发展计划，每个 学员将选择参加为期两年或三年的培训计划，并有机会完成培训 获得临床研究健康科学硕士学位，或攻读免疫学博士学位。学员将选择 来自经验丰富且多样化的16名基础、翻译或临床小组的主要导师 免疫生物学研究人员。在导师的指导下，他们将遵循结构化的教学课程，这将 过渡到有指导的研究体验。强大的研究基础设施和强大的部门 资源将为学生提供支持，促进他们进行和发布原始调查 从临床服务中获得全面保护。将提供免疫学调查方面的具体指导，如 将在科学写作、出版、伦理和临床时间管理方面提供指导。

Project Summary/Abstract Immunobiology has become increasingly relevant to surgical practice, influencing diverse disciplines including oncology, inflammatory bowel disease, transplantation, trauma and critical care. Although the importance of immune manipulation has become an evident adjunct to surgical practice, surgical training neither includes advanced immunology nor prepares surgeon-scientists to participate in immune-related research. This training grant application seeks funding for the formation of the Advanced Immunobiology Training Program (AITP) at Duke University to create surgeon-scientists capable of participating in and leading surgically relevant areas of immunobiological research. The training program will combine the substantial academic rigor of the Duke University School of Medicine with the Duke Department of Surgery's longstanding and highly successful commitment to training the next generation of surgical researchers. The program will be co-directed by an academic surgeon and a basic sciences researcher, each with expertise in immunology. Supplemented by mentors with expertise in basic, translational, and clinical research, this multidisciplinary team is uniquely qualified to merge basic and applied immunobiology with evolving surgical practice. Program participants will consist of postdoctoral trainees who have completed medical school and initiated surgical residency. At least six individuals will be trained during the proposed funding period. Based on individual development plans, each trainee will choose to participate in either a two- or three-year training program, with opportunities to complete a Master of Health Sciences degree in Clinical Research, or pursue a PhD in Immunology. Trainees will select a primary mentor from a highly experienced and diverse group of 16 basic, translational or clinical immunobiological researchers. Guided by their mentor, they will follow a structured didactic curriculum that will transition to a mentored research experience. A robust research infrastructure and substantial departmental resources will support the students, facilitating their conduct and publication of original investigations with complete protection from clinical service. Specific instruction in immunological investigation will be provided, as will mentorship in scientific writing, publication, ethics and clinical time management.