Advanced Immunobiology Traning Program for Surgeons

项目总结/摘要 免疫生物学与外科实践的相关性越来越强，影响着不同的学科，包括 肿瘤学、炎症性肠病、移植、创伤和重症监护。虽然重要的是 免疫操作已成为外科实践的明显辅助手段，外科培训也不包括 高级免疫学也不准备外科医生科学家参与免疫相关研究。本次培训 赠款申请寻求资金的高级免疫生物学培训计划（AITP）的形成， 杜克大学培养能够参与和领导外科相关领域的外科医生科学家， 免疫生物学研究培训计划将联合收割机结合杜克的大量学术严谨 大学医学院与杜克大学外科的长期和高度成功的 致力于培养下一代外科研究人员。该节目将由一位 学术外科医生和基础科学研究员，每个人都有免疫学方面的专业知识。辅以 导师在基础，转化和临床研究的专业知识，这个多学科的团队是独一无二的 有资格将基础和应用免疫生物学与不断发展的外科实践相结合。计划参与者将 由已完成医学院学业并开始外科住院实习的博士后学员组成。至少 在拟议供资期间，将培训6人。根据个人发展计划，每个 学员将选择参加为期两年或三年培训计划， 临床研究健康科学硕士学位，或攻读免疫学博士学位。学员将选择 一位来自经验丰富的多元化团队的主要导师，该团队由16名基础、翻译或临床 免疫生物学研究者在导师的指导下，他们将遵循结构化的教学课程， 过渡到一个指导的研究经验。强大的研究基础设施和大量的部门 资源将支持学生，促进他们的行为和出版的原始调查， 临床服务的全面保护。将提供免疫学研究的具体说明， 将指导科学写作，出版，道德和临床时间管理。

Project Summary/Abstract Immunobiology has become increasingly relevant to surgical practice, influencing diverse disciplines including oncology, inflammatory bowel disease, transplantation, trauma and critical care. Although the importance of immune manipulation has become an evident adjunct to surgical practice, surgical training neither includes advanced immunology nor prepares surgeon-scientists to participate in immune-related research. This training grant application seeks funding for the formation of the Advanced Immunobiology Training Program (AITP) at Duke University to create surgeon-scientists capable of participating in and leading surgically relevant areas of immunobiological research. The training program will combine the substantial academic rigor of the Duke University School of Medicine with the Duke Department of Surgery's longstanding and highly successful commitment to training the next generation of surgical researchers. The program will be co-directed by an academic surgeon and a basic sciences researcher, each with expertise in immunology. Supplemented by mentors with expertise in basic, translational, and clinical research, this multidisciplinary team is uniquely qualified to merge basic and applied immunobiology with evolving surgical practice. Program participants will consist of postdoctoral trainees who have completed medical school and initiated surgical residency. At least six individuals will be trained during the proposed funding period. Based on individual development plans, each trainee will choose to participate in either a two- or three-year training program, with opportunities to complete a Master of Health Sciences degree in Clinical Research, or pursue a PhD in Immunology. Trainees will select a primary mentor from a highly experienced and diverse group of 16 basic, translational or clinical immunobiological researchers. Guided by their mentor, they will follow a structured didactic curriculum that will transition to a mentored research experience. A robust research infrastructure and substantial departmental resources will support the students, facilitating their conduct and publication of original investigations with complete protection from clinical service. Specific instruction in immunological investigation will be provided, as will mentorship in scientific writing, publication, ethics and clinical time management.