Advanced Immunobiology Traning Program for Surgeons

外科医生高级免疫生物学培训计划

基本信息

  • 批准号:
    10396460
  • 负责人:
  • 金额:
    $ 26.24万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-06-01 至 2024-05-31
  • 项目状态:
    已结题

项目摘要

Project Summary/Abstract Immunobiology has become increasingly relevant to surgical practice, influencing diverse disciplines including oncology, inflammatory bowel disease, transplantation, trauma and critical care. Although the importance of immune manipulation has become an evident adjunct to surgical practice, surgical training neither includes advanced immunology nor prepares surgeon-scientists to participate in immune-related research. This training grant application seeks funding for the formation of the Advanced Immunobiology Training Program (AITP) at Duke University to create surgeon-scientists capable of participating in and leading surgically relevant areas of immunobiological research. The training program will combine the substantial academic rigor of the Duke University School of Medicine with the Duke Department of Surgery's longstanding and highly successful commitment to training the next generation of surgical researchers. The program will be co-directed by an academic surgeon and a basic sciences researcher, each with expertise in immunology. Supplemented by mentors with expertise in basic, translational, and clinical research, this multidisciplinary team is uniquely qualified to merge basic and applied immunobiology with evolving surgical practice. Program participants will consist of postdoctoral trainees who have completed medical school and initiated surgical residency. At least six individuals will be trained during the proposed funding period. Based on individual development plans, each trainee will choose to participate in either a two- or three-year training program, with opportunities to complete a Master of Health Sciences degree in Clinical Research, or pursue a PhD in Immunology. Trainees will select a primary mentor from a highly experienced and diverse group of 16 basic, translational or clinical immunobiological researchers. Guided by their mentor, they will follow a structured didactic curriculum that will transition to a mentored research experience. A robust research infrastructure and substantial departmental resources will support the students, facilitating their conduct and publication of original investigations with complete protection from clinical service. Specific instruction in immunological investigation will be provided, as will mentorship in scientific writing, publication, ethics and clinical time management.
项目总结/摘要 免疫生物学与外科实践的相关性越来越强,影响着不同的学科,包括 肿瘤学、炎症性肠病、移植、创伤和重症监护。虽然重要的是 免疫操作已成为外科实践的明显辅助手段,外科培训也不包括 高级免疫学也不准备外科医生科学家参与免疫相关研究。本次培训 赠款申请寻求资金的高级免疫生物学培训计划(AITP)的形成, 杜克大学培养能够参与和领导外科相关领域的外科医生科学家, 免疫生物学研究培训计划将联合收割机结合杜克的大量学术严谨 大学医学院与杜克大学外科的长期和高度成功的 致力于培养下一代外科研究人员。该节目将由一位 学术外科医生和基础科学研究员,均拥有免疫学专业知识。辅以 导师在基础,转化和临床研究的专业知识,这个多学科的团队是独一无二的 有资格将基础和应用免疫生物学与不断发展的外科实践相结合。计划参与者将 由已完成医学院学业并开始外科住院实习的博士后学员组成。至少 在拟议供资期间,将培训6人。根据个人发展计划,每个 学员将选择参加为期两年或三年培训计划, 临床研究健康科学硕士学位,或攻读免疫学博士学位。学员将选择 一位来自经验丰富的多元化团队的主要导师,该团队由16名基础、翻译或临床 免疫生物学研究者在导师的指导下,他们将遵循结构化的教学课程, 过渡到一个指导的研究经验。强大的研究基础设施和大量的部门 资源将支持学生,促进他们的行为和出版的原始调查, 完全保护临床服务。将提供免疫学研究的具体说明, 将指导科学写作,出版,道德和临床时间管理。

项目成果

期刊论文数量(0)
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Allan D. Kirk其他文献

Anti-IL12/23 synergizes with costimulatory blockade to prolong transplant survival
  • DOI:
    10.1016/j.jamcollsurg.2011.06.162
  • 发表时间:
    2011-09-01
  • 期刊:
  • 影响因子:
  • 作者:
    William H. Kitchens;Andrew B. Adams;Allan D. Kirk;Christian P. Larsen;Mandy L. Ford
  • 通讯作者:
    Mandy L. Ford
Necrosis and immune activation: does tissue death alter acquired alloimmunity?
  • DOI:
    10.1016/j.jamcollsurg.2013.07.331
  • 发表时间:
    2013-09-01
  • 期刊:
  • 影响因子:
  • 作者:
    Salila S. Hashmi;Mandy L. Ford;Christian P. Larsen;Allan D. Kirk
  • 通讯作者:
    Allan D. Kirk
B cells and transplantation tolerance
B 细胞与移植耐受
  • DOI:
    10.1038/nrneph.2010.111
  • 发表时间:
    2010-08-24
  • 期刊:
  • 影响因子:
    39.800
  • 作者:
    Allan D. Kirk;Nicole A. Turgeon;Neal N. Iwakoshi
  • 通讯作者:
    Neal N. Iwakoshi
Assessing Quality of Real-World Data Supplied by an Automated Surgical Data Pipeline
  • DOI:
    10.1016/j.jamcollsurg.2019.08.203
  • 发表时间:
    2019-10-01
  • 期刊:
  • 影响因子:
  • 作者:
    Kristin Corey;Joshua Helmkamp;Allan D. Kirk;Suresh Balu;David Thompson;Leila Mureebe;Joshua Watson;Keith Marsolo;Lesley Curtis;Mark Sendak
  • 通讯作者:
    Mark Sendak
Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients
  • DOI:
    10.1016/j.jamcollsurg.2016.06.346
  • 发表时间:
    2016-10-01
  • 期刊:
  • 影响因子:
  • 作者:
    Marcus D. Darrabie;Jaewoo Lee;Jennifer Cheeseman;Alexander T. Limkakeng;Steven N. Vaslef;Bruce A. Sullenger;Allan D. Kirk
  • 通讯作者:
    Allan D. Kirk

Allan D. Kirk的其他文献

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{{ truncateString('Allan D. Kirk', 18)}}的其他基金

Advanced Immunobiology Traning Program for Surgeons
外科医生高级免疫生物学培训计划
  • 批准号:
    10598547
  • 财政年份:
    2019
  • 资助金额:
    $ 26.24万
  • 项目类别:
Depletion, Repopulation and Tolerance in Non-Sensitied Recipients
非敏感受体的消耗、再生和耐受性
  • 批准号:
    9980790
  • 财政年份:
    2017
  • 资助金额:
    $ 26.24万
  • 项目类别:
Computational Immunobiology Core
计算免疫生物学核心
  • 批准号:
    10622057
  • 财政年份:
    2017
  • 资助金额:
    $ 26.24万
  • 项目类别:
Depletion, Repopulation and Tolerance in Non-Sensitied Recipients
非敏感受体的消耗、再生和耐受性
  • 批准号:
    10214495
  • 财政年份:
    2017
  • 资助金额:
    $ 26.24万
  • 项目类别:
Depletion, Repopulation and Tolerance in Non-Sensitied Recipients
非敏感受体的消耗、再生和耐受性
  • 批准号:
    10649945
  • 财政年份:
    2017
  • 资助金额:
    $ 26.24万
  • 项目类别:
Cell Adhesion and Trafficking as a Therapeutic Target in Allotransplantation
细胞粘附和运输作为同种异体移植的治疗靶点
  • 批准号:
    8705985
  • 财政年份:
    2014
  • 资助金额:
    $ 26.24万
  • 项目类别:
T Cell Maturation and the Nexus of Viral- and Allo-Immunity
T 细胞成熟以及病毒免疫和同种异体免疫的关系
  • 批准号:
    8371823
  • 财政年份:
    2012
  • 资助金额:
    $ 26.24万
  • 项目类别:
T Cell Maturation and the Nexus of Viral- and Allo-Immunity
T 细胞成熟以及病毒免疫和同种异体免疫的关系
  • 批准号:
    8463978
  • 财政年份:
    2012
  • 资助金额:
    $ 26.24万
  • 项目类别:
T Cell Maturation and the Nexus of Viral- and Allo-Immunity
T 细胞成熟以及病毒免疫和同种异体免疫的关系
  • 批准号:
    8607811
  • 财政年份:
    2012
  • 资助金额:
    $ 26.24万
  • 项目类别:
ADJUVANT THERAPIES IMPROVING ANTI-REJECTION EFFECTS OF COSTIMULATION BLOCKADE
辅助疗法改善共同刺激封锁的抗排斥效果
  • 批准号:
    8357527
  • 财政年份:
    2011
  • 资助金额:
    $ 26.24万
  • 项目类别:

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促进耳鼻喉头颈外科外科医生科学家的职业生涯
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与 AD/ADRD 患者手术结果的种族和民族差异相关的外科医生和医院因素
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外科医生因素和教育/培训对外科护理差异的影响。
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外科医生因素和教育/培训对外科护理差异的影响。
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