20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCU

20/21 ABCD-美国联盟：弗吉尼亚联邦大学研究项目现场

• 批准号: 10399189
• 负责人: James M Bjork
• 金额: $ 1.21万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-15 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10399189
• 关键词: 10 year old; Acute; Address; Adolescent; Affect; Age; Alcohol consumption; Alcohols; Anxiety; Athletic Injuries; Bachelor' s Degree; Behavior; Big Data; Bioinformatics; Biological Assay; Biomedical Research; Brain; Caffeine; Calendar; Cannabis; Child; Childhood; Clinical Trials; Cognition; Cognitive; Communities; Complex; Data; Data Analyses; Data Collection; Decision Making; Development; Emotional; Enrollment; Ensure; Environment; Environmental Exposure; Environmental Risk Factor; Epidemiology; Ethics; Exclusion; Family; Feeling suicidal; Female; Funding; Genetic; Health Benefit; Immersion; Impairment; Individual; Informatics; Link; Logistics; Mental Depression; Mental Health; Mental disorders; Methodology; Methods; Monitor; National Institute of Drug Abuse; Neurocognition; Neurocognitive; Neurosciences; Neurosciences Research; Occupations; Olives - dietary; Outcome; Parents; Participant; Persons; Physical activity; Population; Poverty; Procedures; Process; Protocols documentation; Psychopathology; Registries; Research; Research Personnel; Research Project Grants; Resources; Risk; Role; Scanning; Schools; Science; Seasons; Severities; Siblings; Site; Sleep; Social isolation; Specific qualifier value; Standardization; Teenagers; Telephone; Testing; Text; Time; Tobacco; Tobacco use; Training; Traumatic Brain Injury; Triplet Multiple Birth; Twin Multiple Birth; Universities; Virginia; Visit; Youth; adolescent substance use; adverse outcome; biomedical scientist; burnout; career; cognitive development; cognitive task; cohort; college; data harmonization; design; emerging adult; emotional factor; experience; follow-up; gene interaction; grasp; human subject; improved; informatics infrastructure; interest; marijuana use; member; mobile computing; neurobehavioral; neurodevelopment; neuroimaging; novel; operation; participant retention; physical conditioning; prevent; programs; public health research; racial minority; recruit; relating to nervous system; research and development; response; retention rate; substance use; trend; tv watching

Project summary Persons from marginalized communities are underrepresented in biomedical research as participants (1) such as in clinical trials (2). There is an especially acute dearth of individuals from racial minorities as biomedical scientists, including neuroscience (3). This under-representation results in reduced perspectives on culturally- sensitive assessments for neurobehavioral and neuroscience research (4), but also impoverishes public health research initiatives that may benefit health of racial minorities. This exclusion also necessitates generalization of clinical trial data of whites to other populations in the absence of data for proper inference. Therefore, to help improve inclusion in neuroscience research, the Virginia Commonwealth University (VCU) site of the Adolescent Brain Cognitive Development (ABCD) study (5) seeks supplemental funding to provide an immersive human- subject biomedical research experience to Olive Calonge, who is graduating from Stony Brook University Spring 2021. They (preferred pronoun) have been selected among a highly competitive pool of applicants to the NIDA program for immersive biomedical experiences, and have expressed an interest in developmental neuroscience. Olive will be tasked with testing on-site families (VCU is fully-open for all ABCD procedures, but with physical/spatial distancing). This would include scan-year and “off-year” visits. We believe that the team could benefit from additional on-site help for these in-person visits to prevent staff burnout during peak accrual season (late Spring and Summer). Olive will be afforded opportunities to perform all tasks typical of bachelor's degreed RAs short of conducting (as sole staff member) neuroimaging sessions with cognitive task operation and a handful of other more complex tasks that require careful training and cross-site harmonization. We are confident that this hands-on interpersonal research experience will enable Olive to have a comprehensive grasp of many of the regulatory and other complexities of cross-site big-data harmonized descriptive neuroscience data collection, to further enable their career to unfold in the neurosciences.

项目摘要 来自边缘化社区的人作为参与者参与生物医学研究的人数不足（1）， 临床试验（2）。作为生物医学专家的少数种族的人特别缺乏， 科学家，包括神经科学（3）。这种代表性不足导致对文化的看法减少， 神经行为和神经科学研究的敏感评估（4），但也危及公共卫生 可能有益于少数民族健康的研究举措。这种排除也需要推广 在缺乏数据进行适当推断的情况下，将白人的临床试验数据用于其他人群。因此，为了帮助 改善神经科学研究的包容性，弗吉尼亚联邦大学（VCU）的青少年网站 大脑认知发展（ABCD）研究（5）寻求补充资金，以提供一个沉浸式的人类- 将生物医学研究经验传授给即将从斯托尼布鲁克大学春季班毕业的奥利弗卡隆格 2021.他们（首选代词）是从竞争激烈的NIDA申请者中挑选出来的 沉浸式生物医学体验计划，并表示对发育神经科学感兴趣。 Olive将负责测试现场家庭（VCU对所有ABCD程序完全开放，但 物理/空间距离）。这将包括扫描年和“非扫描年”的访问。我们相信这个团队可以 受益于这些亲自访问的额外现场帮助，以防止工作人员在应计高峰期过度疲劳 (late春天和夏天）。Olive将有机会完成学士学位的所有典型任务 RA缺乏进行（作为唯一的工作人员）具有认知任务操作的神经成像会话， 其他一些更复杂的任务，需要认真的培训和跨站点的协调。我们相信 这种亲身实践的人际研究经验将使Olive能够全面掌握许多 跨站点大数据协调描述性神经科学数据的监管和其他复杂性 收集，以进一步使他们的职业生涯在神经科学中展开。